James Hane

Senior Research Fellow, Project Leader - Advanced Bioinformatics @ CCDM/Curtin, Interests: fungal genomics, plant pathology, effectors.

[CCDM @theCCDM]

💻 Student Spotlight 💻
Meet PhD student Naomi Gray, whose research at CCDM uses advanced bioinformatics to uncover how fungal pathogens specialise to infect crops—supporting smarter disease diagnosis and surveillance for growers.
@theGRDC @CurtinUni

[James Hane @JamesKHane]

Our new effector discovery tool EffectorFisher, a GWAS-alternative which combines pangenome-mined protein-isoform profiles and disease phenotyping, tested on P. nodorum and Z. tritici https://t.co/ViqmKvtLkw @theCCDM

[CCDM @theCCDM]

Congratulations to @JamesKHane & @drjuliaeaston - now Associate Professors!

James builds bioinformatics power to fight crop disease.
Julia leads C4AP for farm profitability & sustainability.

CCDM is proud to foster talent & advance agriculture! 🌱

@GRDC, @Curtinuni

[CCDM @theCCDM]

CCDM made a big impact at MLS Symposium 2025! 🎉

Congrats to our award winners:
🏆 Viet-Cuong Han – Graeme Robertson Award
🎤 Nimllash Thangam & Naomi Gray – Best Oral Presentation
📊 Mohitul Hossain – Best Poster

@theGRDC @CurtinUni

[James Hane @JamesKHane]

Well done to @theCCDM bioinformatics Ph.D. students @MohitulHossain and Naomi Gray who presented posters at @ISMPMI #2025ISMPMI

[James Hane @JamesKHane]

Congratulations to @theCCDM PhD student @MohitulHossain , who gave an excellent presentation today in the New Researcher Session at #GRDCUpdates, on our new methods for phenotype-associated effector prediction and pangenome-based effector and fungicide-resistance screening.

[CCDM @theCCDM]

🌾Pathogens are constantly evolving to outsmart crops! Our team analyzed 173 isolates of Stagonospora nodorum blotch fungus🧬They found it uses mutations like RIP to diversify—while harmful mutations are filtered out🦠 📰 https://t.co/kzC6IRaRVc
@theGRDC @CurtinUni @JamesKHane

[James Hane @JamesKHane]

Our latest paper shows RIP is a strong driver of genomic diversity in fungal pathogens, yet few mutations end up influencing protein diversity. Nevertheless, their potential to rapidly adapt to changing conditions is only ever one generation away.

https://t.co/zSJ0HmU4S6

[Communications Biology @CommsBio]

A pangenome of 173 isolates of Parastagonospora nodorum, a necrotrophic fungal pathogen of wheat, showed widespread potential for RIP-like SNPs across the genome, balanced by negative selection against non-synonymous changes in protein-coding regions.

https://t.co/pp3YI1psxm

[James Hane @JamesKHane]

Well done to @theCCDM Advanced Bioinformatics Approaches PhD students Naomi Gray and @MohitulHossain, presenting posters on pangenomics and effector discovery for plant-pathogenic fungi today at #IWC2024Perth

[James Hane @JamesKHane]

Well done to @theCCDM Advanced Bioinformatics Approaches students @MohitulHossain Naomi Gray and Pavel Misiun who presented posters at #PAGAustralia this week!

[James Hane @JamesKHane]

Two recent genome publications on pathogens of Pistachio and Pomegranate, in collaboration with Antonios Zambounis of ELGO—DIMITRA:
https://t.co/j4yVC7OShg
https://t.co/bPY1ALkLz2

[James Hane @JamesKHane]

Well done to @theCCDM Advanced Bioinformatics Approaches students @MohitulHossain who gave a student presentation, Naomi Gray and Pavel Misiun who presented posters at #CBSM2024 last Friday!

[James Hane @JamesKHane]

https://t.co/b6y2FP7mdg

[James Hane @JamesKHane]

Know when to hold them... https://t.co/FEB2rFhlhT

[James Hane @JamesKHane]

https://t.co/pNP8PRLDIw

[James Hane @JamesKHane]

@theCCDM 's Dr @karchuntan presenting at the #pag23 @PAGmeeting on Phytophthora cinnamomi proteogenomics

[CCDM @theCCDM]

Our PhD students @MohitulHossain and Naomi Gray have been busy getting involved at #PAGAustralia the last few days! Check out their posters all about their work on pan-genome and fungicide resistance allele profiling and pan-genomes of crop pathogens. #PAG23 @PAGmeeting

[CCDM @theCCDM]

Today we had the pleasure of hosting the board members from @theGRDC @GrainProducers and @GrainGrowersLtd for a visit. We showcased our state-of-the-art facilities and introduced them to our dedicated staff, who are working tirelessly to mitigate the impact of crop diseases

[CCDM @theCCDM]

What do fungal diseases and snakes have in common? They attack in similar ways! Our researchers have modeled the 3D structures of fungal effector proteins and found some are similar to animal venom and plant defensins. https://t.co/gBlwhwj1BM | https://t.co/1yMjrhmB8W @JamesKHane