We’re honored to rename our DSMB training program the Bristow–DeMets DSMB Academy, recognizing the extraordinary contributions of Michael Bristow, MD, PhD and David DeMets, PhD to clinical trials, patient safety, and the generations of researchers they have inspired. #hfc
Dr. Gerard Slobogean describes how orthopaedics is embracing adaptive platform trials and Bayesian analytics, with clinicians showing strong interest in structured, probability-based approaches.
Weekly inquiries about new platform opportunities reflect a shift toward a learning health system—one where each answered question leads directly to the next, advancing patient-centered orthopaedic research.
This environment fosters more structured trial activation and supports investigators in efficiently evaluating interventions.
Gain more insights into this fascinating topic by listening to the latest episode of "In the Interim..." https://t.co/Y15VwDdOiP
@BHonestALC@LocasaleLab I’m thankful I’m merely tangentially academic (for so many reasons).
I do some NIH study sections but am an independent consultant.
I can and do say what I want and don’t have to play the games.
And it’s kinda fun being the one disagreeing and pushing.
@jewishgengar@matthewherper@Pharmdca I think anyone who knows the process wants a little cross-pollination.
Just like I’d rather have FAA people who are pilots or have built planes and maybe seen Boeing from the inside.
We too frequently have individuals who’ve never designed or run a trial evaluating trials.
@matthewherper Given DOGE at the beginning of the administration and general dislike of career federal workers of Trump, do you think any other commissioner starting in early 2025 would have had different results?
@olumidetheeel@kathrynw5 You might know them, but do you talk to them deeply, do you KNOW them?
That’s the issue.
I grew up where only teachers had a BS. Now I live where most have a graduate degree. The bubbles are real.
@charlesornstein Didn’t politicians always oppose journalists doing their good work?
And didn’t journalists just do it anyway?
That’s the idea of a free press.
@kcwrote@benryanwriter That’s rough. At least I never had that.
I did have a friend who dated 4 straight Heathers.
There was much debate if it was simply due to the ubiquity of Heathers in 1998 or whether he, in fact, had a Heather-fetish.
@benryanwriter And Ethans and Graysons and Hudsons and Owens
And when we went to ToysRUs to buy the big letters to spell out our daughter’s name above her crib … they were out of N’s!
No kidding.
@benryanwriter I did read about 17 years ago when we were picking baby names that 35% of white boys in the USA were 2 syllables and ended in N.
And sure enough when my daughter got to kindergarten her class was full of Logan’s, Carson’s, Jackson’s, and Mason’s
So we Jasons were trendsetters.
@quirkyllama@gcochran99@cremieuxrecueil But it’s been replicated in numerous studies now.
Ruth Itzhaki at Oxford has been adamant about the viral component of Alzheimer’s for years. Now we have evidence.