Jean Regina

PGY-4 in Switzerland. Interested in internal medicine, ID, clinical reasoning and research on low value care.

[Jean Regina @JeanThomasR]

@Giguere_P @anish_koka @AnilMakam In my experience, the complicated part is the baseline risk for my individual patient. Hard to estimate and most of the time oncologists are too optimistic.

[Jean Regina @JeanThomasR]

@Giguere_P @anish_koka @AnilMakam Real interested question: how should we approach it then?

[Jean Regina @JeanThomasR]

@tony_breu @tony_breu very interesting! What about mitral stenosis ?

[Jean Regina @JeanThomasR]

@ApuAkkad1 @ABsteward @BradSpellberg @DrToddLee Antibiotics as a delirium ttt in older inpatients, prealbumin to measure nutritional status in highly inflammed patients

[Jean Regina @JeanThomasR]

@DrToddLee @ABsteward I guess it is! Anyways, the majority of hospitalists I know already changed their practice ;-)

[Jean Regina @JeanThomasR]

@DrToddLee @ABsteward @DrToddLee do you know when it will be published?

[Jean Regina @JeanThomasR]

@DrToddLee @ABsteward @TimLaheyMD @BradSpellberg Looking forward to generating new evidence for elderly patients with your team !

[Jean Regina @JeanThomasR]

@ABsteward @DrToddLee LIPS: combination of antibiotic treatment with linezolid for SAB

[Jean Regina @JeanThomasR]

@ABsteward @DrToddLee A linezolid RCT is ongoing in Switzerland: https://t.co/GDT6NP5Ivq

[Jean Regina @JeanThomasR]

@DrToddLee @LucusHumphrey Well done ! If marathon now feels too easy and you want a different type of challenge, you can come to Switzerland and try the classic Sierre-Zinal mountain race ;)

[Jean Regina @JeanThomasR]

@ABsteward Thx for sharing, it confirms our findings in a Swiss cohort: https://t.co/Da9Yz0m2rO

[Jean Regina @JeanThomasR]

@ABsteward Residual confounding ? Hard to believe that patient without de-escalation weren't a bit sicker (higher ICU admission and death)

[Jean Regina @JeanThomasR]

@nickmmark And the editors ?

[Evidence Rounds @EvidenceRounds]

For older adults w/ newly diagnosed afib during hospitalization the 1-yr stroke risk w/o anticoag was low: 0.7% for CHA2DS2VASc 1-4 & 1.8% for 5-8

Given consensus of ≥2%/year, anticoag may be less compelling in hospital-detected AF but should still be individualized by risk

[Jean Regina @JeanThomasR]

@AnilMakam @AnilMakam I've read the pre Submission version of this manuscript and that was exactly my conclusion too.

[Jean Regina @JeanThomasR]

@AnilMakam @DrToddLee Recurrence is frequent - 1/3 at 1y in the AFOTS trial, https://t.co/7ucEQ1A8Na, and probably influences stroke risque. I don't ac patients but share these data with them so that they are aware of the possibility of recurrence and of the need to see their GP if it occurs.

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

"The other evening, I received two normally welcome email alerts. The first informed me that an invitation to peer review had been accepted; the second, that a peer review had just been completed.
The problem? These two emails came seven minutes apart and concerned the same reviewer"
https://t.co/9xsvjfxlqG

[Evidence Rounds @EvidenceRounds]

Happy new year!

To bring in 2026, let's rewind

Here are the 2025 evidence updates for hospital medicine

Paired with EBM teachable moments

[Jean Regina @JeanThomasR]

@drjohnm "I mean what is that image on the left?" I think it's a heart but I don't know what it's supposed to mean.

[Clinical Infectious Diseases @CIDJournal]

Rethinking the routine: Are repeat blood cultures necessary after completion of infective endocarditis treatment?

✅ Just Accepted
🔗 https://t.co/z253GTWxds