“I kept pulling the books out of the shelves again and again. I could only read a few lines and I felt the fakeness and I put them back. It was a real horror show. Nothing related to life, at least not to mine and the streets and the people I saw in the streets and what they were forced to do and what they became.”
~ Bukowski
Emerging data from clinical trials points to potentially powerful use of psilocybin for the treatment of depression and certain forms of addiction, and perhaps compulsive disorders, too.
One of the key questions to arise from those studies is: "what is the relationship between the actual journey (the subjective experience under the influence of psilocybin) and the improvements in mood and other thought patterns that persist afterwards"?
If you think about it, this is a critical issue to resolve because it needn't be the case that the actual journey and insights therein are the cause of the antidepressant effects. The rewiring (neuroplasticity) events in the brain could, for instance, occur afterwards or be independent of the subjective experience of the journey. Or they could simply be the consequence of the serotonin receptor activation and strengthening of certain neural connections, or even neurogenesis.
During the Huberman Lab episode out now, I discuss the data related to all of these issues. I also discuss safety considerations, and who should absolutely avoid psilocybin, which, of course are critical issues. https://t.co/X7tKttfOku
"Solitary men : Some men are so accustomed to being alone with themselves that they do not compare themselves with others at all but spin out their life of monologue in a calm and cheerful mood, conversing and indeed laughing with themselves alone."
Friedrich Nietzsche
Fascinating data on how the experience of anxiety, feelings of “mystical-level boundlessness”, dissolution of self & the return to calm & self identification, each relate to therapeutic benefits of psilocybin. Mechanisms, unknowns & risks covered here:
https://t.co/STdSXpfZ0k
it's not aliens
i wish it were aliens
but it's not aliens
it's just the ol' engineered panic, an attractive nuisance ensuring natsec reporters get assigned to investigate balloon bullshit rather than budgets or bombings (à la nordstream)
until next time