Jessica Lu

Postdoctoral Research Associate @BiochemOxford 🔬

[Cesare Orlandi @orlandi_cesare]

Our GzESTY paper is online. We optimized a cell based assay to sensitively detect GPCR activation in response to ligand application or in complex mixtures containing endogenous ligands. GzESTY was designed to aid in GPCR deorphanization efforts.
https://t.co/zJ5P5Fo0vS

[Terry Hébert @THebertMcGill]

Molecular glues becoming a thing in the GPCR world!

https://t.co/BGDESM59UH

https://t.co/h55N2TeRt5

[GPCRmd @GPCRmd]

🔬 The 2nd round of GPCRmd data is out! Covering 60% of GPCR structures, it reveals allosteric sites & lateral gateways into the receptor core.

🔗 Read: https://t.co/3nS4RYFZJy

#GPCR #GPCRmd #MolecularDynamics

Explore it with our new tools: https://t.co/JE7zdVdM7d

[Alejandra Tomás Catalá @TomasLab_ICL]

Still time to apply to this position! Application open until 15th Jan 2025.

[Membrane Protein PDB @MemProtPDB]

GABAA receptor π forms channels that stimulate ERK through a G-protein-dependent pathway | Molecular Cell

https://t.co/N8yhWMxQ9K

[Membrane Protein PDB @MemProtPDB]

Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function | Nat Commun

https://t.co/QiMScPZody

[Ben Myers Lab @Myers_lab]

Excited to share our new preprint on the #Hedgehog pathway! We uncover how #Smoothened (SMO), a noncanonical #GPCR, binds & inhibits #PKA via an intrinsically disordered region, mimicking known GPCR/PKA signaling complexes despite minimal sequence similarity. #AlphaFold #IDR

[Structure @Structure_CP]

Online now! Native mass spectrometry prescreening of G protein-coupled receptor complexes for cryo-EM structure determination https://t.co/WC9YMolc4H

[Receptor Biology Lab @StuartMaudsley]

...worth taking a look at if you're into G protein-coupled receptors (#GPCRs), a great series of lectures by a good friend of mine!

[Charles Bayly-Jones @bj_charles]

We are thrilled beyond words to see our LYCHOS (GPR155) publication out today in @Nature. 🥳

“LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR”
https://t.co/I7ibRphMzS

🧵

[Wnt UK @UK_Wnt]

📔SAVE THE DATE! 🗓️

The 2nd WntUK national meeting will be held at @WorcCollegeOx @UniofOxford on Monday 24th March 2025.

Registration and abstract submission opens November 2024.

Wnt researchers of all levels and disciplines welcome from the UK and beyond!

[Michael Ranes @MSRanes]

👇🏾👀🥳...Wnt is coming to town next year 🙌🏾

[ECI GPCR symposium @cool7TMs]

Tomorrow is THE DAY! 🎉
We're kicking off the #4th_Transatlantic_ECI_GPCR_Symposium. This is the final reminder for registration!
Besides the amazing keynote speakers, and career and lunch/dinner panelists, we have wonderful #ECI speakers who will present their latest research!

[Jessica Lu @Jessica_J_Lu]

Congrats @SarahJ_Piper and @brianpcary !

[ARC CCeMMP @CCeMMP]

Big congrats to our #CCeMMP members for their 2025 @arc_gov_au #DECRA awards! 💫🏆🎊

@SarahJ_Piper Understanding structure, dynamics and function of receptor splice variants
@brianpcary - Leveraging electron microscopy to study receptor structure and function.

@MIPS_Australia

[ARC CCeMMP @CCeMMP]

Big congrats to our #CCeMMP members for their 2025 @arc_gov_au #DECRA awards! 💫🏆🎊

@SarahJ_Piper Understanding structure, dynamics and function of receptor splice variants
@brianpcary - Leveraging electron microscopy to study receptor structure and function.

@MIPS_Australia

[ARC CCeMMP @CCeMMP]

Our @arc_gov_au CCeMMP 'Bench to Art' Exhibition is now open to the public for @Aus_ScienceWeek 🤩 with 28 amazing entries from around the world! Check out the link below and vote for your favourite artwork in the People's Choice Award. 🏆https://t.co/MBpKcSV21w

#Scienceweek

[Ben Myers Lab @Myers_lab]

Now published in @PLOSBiology: How GRK kinases control #GPCR signaling in the #Hedgehog transduction cascade in primary #cilia.

https://t.co/BRi7tOMZ4A

[Structura Biotechnology @structurabio]

Working on #cryoEM for membrane proteins?

This new #CryoSPARC case study covers end to end advanced processing of a 73 kDa inactive state GPCR, including challenges and pitfalls, detailed figures and final maps. Read in full here: https://t.co/5Xtl0zYID2

[Jessica Lu @Jessica_J_Lu]

Congrats @PatrickMSexton1 !

[NHMRC @nhmrc]

Congratulations to the recipient of Peter Doherty Investigator Grant Award in Leadership, @PatrickMSexton1 of @MIPS_Australia, @CCeMMP and @MIPS_DDB for his research on improving our understanding of G protein-coupled receptors. Read more on our website: https://t.co/e3uR3nlBCs

[Sepideh Valimehr @SValimehr]

Don't miss out! The 10th International Conference on Electron Tomography is from January 28-30, 2025, in Melbourne.Registration is open now!
https://t.co/tTnfLmVAAg
#CryoEM #Tomography #TEM