I am thrilled to share our latest article on understanding the role of lipid regulations' on cancer stem cell behavior. I am so grateful for the mentorship and supports of Wenjun @WenjunGuoLab. I also want to express my appreciation to all the co-authors. Thank you all.
How do lipids control cancer stem cells? In this @ScienceAdvances paper led by @Jihong_Cui, we found high levels of ABCA12 lipid transporter in breast CSCs reduce intracellular ceramide to activate the YAP/TAZ-SOX9 stemness program and chemoresistance. https://t.co/OtE8MGo73Y
🤯 The @WenjunGuoLab and collaborators showed that deletion of the epigenetic regulator MLL3, a tumor suppressor frequently altered in human cancer, promoted the acquisition of hybrid EMT in #BreastCancer cells! @Einstein_SCI@NIDDKgov@NatureCellBio | https://t.co/p4M1CXPZ96
Great start of 2023. I am so happy to share our recent work @NatureCellBio . Many many thanks to @WenjunGuoLab. And thanks a lot to all co-authors. Can't make it without all of you.😊😊
Excited to share our latest work @NatureCellBio, identifying a role of MLL3/KMT2C mutations in allowing cancer cells to acquire highly metastatic hybrid EMT state. Spearheaded by @Jihong_Cui, great teamwork with Kai Ge, @zhengdy, @DanweiHuangfu groups. https://t.co/OsYpaCfgQA
Excited to share our latest work @NatureCellBio, identifying a role of MLL3/KMT2C mutations in allowing cancer cells to acquire highly metastatic hybrid EMT state. Spearheaded by @Jihong_Cui, great teamwork with Kai Ge, @zhengdy, @DanweiHuangfu groups. https://t.co/OsYpaCfgQA