JohanPijnenborg

[JohanPijnenborg @JohanPijnenborg]

Find out more in the @radboudscience press release: https://t.co/QbVVPtCz9Z

[JohanPijnenborg @JohanPijnenborg]

I am excited to share our latest work published in @NatureComms on the design, synthesis and evaluation of Fucotrim as new cellular fucosulation inhibitors https://t.co/3JG65coLiX
#glycotime #fucose 🔺

[Nature Reviews Drug Discovery @NatRevDrugDisc]

The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans https://t.co/D1tPsVANyV - this new review by Benjamin Smith and @CarolynBertozzi highlights experience and therapeutic opportunities in a field that is becoming increasingly tractable

[JohanPijnenborg @JohanPijnenborg]

Four weeks ago I shared our work inhibiting cellular fucosylation via the de novo pathway. Today, I proudly share our new fucosylation inhibitors acting via the salvage pathway! Both approaches can help study fucose and are potential therapeutic strategies. #glycotime #fucose 🔺

[ChemRxiv @ChemRxiv]

Cellular Fucosylation Inhibitors Based on Fluorinated Fucose-1-Phosphates by Thomas Boltje & co-workers

https://t.co/31G3337c2v

[ChemRxiv @ChemRxiv]

Fluorinated Mannosides Inhibit Cellular Fucosylation. by Thomas Boltje & co-workers

https://t.co/WvQdtcHL47

[JohanPijnenborg @JohanPijnenborg]

Proud to share this work from my PhD research. We designed, synthesized and evaluated a new class of fucosylation inhibitors. These compounds are potent, cell active and directly inhibit de novo biosynthesis of fucose. A special thanks to all collaborators! #glycotime #fucose 🔺

[glycopreprint @glycopreprint]

Fluorinated Mannosides Inhibit Cellular Fucosylation. https://t.co/A2qfgcCLA5 #glycotime

[JohanPijnenborg @JohanPijnenborg]

I am very happy to share this work I contributed to during my stay in the Bertozzi lab. Congrats to the team and in particular @Melissa_Gray234!

[INNOGLY COST Action @InnoglyA]

A fantastic opportunity with a Glyco Taste: Assistant Professor of Biological Neurochemistry (Tenure Track) https://t.co/o6WR7AK1PK via @Radboud_Uni #glycotime

[JohanPijnenborg @JohanPijnenborg]

@StacyMalaker @YaleChem Congrats Stacy!

[JohanPijnenborg @JohanPijnenborg]

The Boltje group is hiring! Challenging opportunity for a PhD-candidate interested to work in the field of carbohydrate synthesis, elucidating the mechanism of chemical glycosylations. https://t.co/Uh3t5e2YfI

[Alison Wendlandt @AlisonWendlandt]

Our lab's first publication is now online. Congratulations Yong and Hayden!! @YongWang_2013
https://t.co/E46hatEr4P

[glycopreprint @glycopreprint]

Characterization of Glycosyl Dioxolenium Ions and Their Role in Glycosylation Reactions https://t.co/YXf4HT3g7e #glycotime

[ChemRxiv @ChemRxiv]

Targeted Desialylation Overcomes Glyco-Immune Checkpoints and Potentiates the Anticancer Immune Response in Vivo by Carolyn Bertozzi (@CarolynBertozzi) & co-workers

https://t.co/cwhre5FdaP