Jonathan Lasham

Postdoc at the University of Helsinki. Interested in computational chemistry and biophysics.

[Noora Aho @noora_aho]

If you are interested in simulating protein crystals or using constant pH MD, our proof-of-concept work with @pbuslaev1 and G. Groenhof combining these two has just been published:
https://t.co/gOjEmhxHiK
How nice it feels to wrap up some older work from PhD times🔥

[Vivek Sharma @vivekvivsharma]

Check our new article in @BBAjournals. Joint work with @JonathanLasham @Amina93364815 #GeorgiosKolypetris @JanetVonck #VolkerZickermann

[Vivek Sharma @vivekvivsharma]

Happy to share our recent review on #mitochondrial complex I mechanism in #biochemj @Biochem_Journal. Work by @Amina93364815 @JonathanLasham #OleksiiZdorevskyi #VolkerZickermann.

[Vivek Sharma @vivekvivsharma]

Happy to share our new article in @JPhysChem.
https://t.co/2Sfycjb6Em

#MDsimulations by @JonathanLasham @Amina93364815. #CryoEM analysis by @JanetVonck @Amina93364815 Volker Zickermann.

[Vivek Sharma @vivekvivsharma]

Happy to contribute to Nanobody engineering for SARS-CoV-2 neutralization and detection | Microbiology Spectrum https://t.co/m5NcENAbPJ

#MDsimulations on RBD of #SARSCoV2 and nanobody @JonathanLasham

@CSCfi @SigridJuselius @SuomenAkatemia #Erkkosäätiö @KumpulaScience

[Vivek Sharma @vivekvivsharma]

Very proud of @JonathanLasham for his successful completion of doctoral degree. And, special thanks to Professor Ville Kaila @TheKailaLab for being the opponent and a great discussion.

[Vivek Sharma @vivekvivsharma]

Check our new article - Role of protonation states in stability of molecular dynamics simulations of high-resolution membrane protein structures
https://t.co/tvyYgMX5Ck
Main points below.

[Vivek Sharma @vivekvivsharma]

Check our new article in @ChemicalScience

Horizontal proton transfer across the antiporter-like subunits in mitochondrial respiratory complex I

Multiscale simulation work by Oleksii Zdorevskyi, @Amina93364815 and @JonathanLasham

https://t.co/bxSM5APc1O

[Outi Haapanen @OutiHaapanen]

In January I started playing with Blender and here is my first take on the respiratory supercomplex! I used #Molecularnodes by @bradyajohnston to make the representations and was delighted to see it works beautifully with coarse grained data too! #sciart #blender #b3d

[Vivek Sharma @vivekvivsharma]

Check our new article on Yarrowia lipolytica complex I. MD simulations by @JonathanLasham and @OutiHaapanen. Thanks to excellent collaboration with Volker Zickermann.

https://t.co/jhfOp3LOSy

[Vivek Sharma @vivekvivsharma]

Happy to contribute to
https://t.co/VYNqcyymTU. MD simulation work by @JonathanLasham. @KumpulaScience @BIOTECH_UH
Thanks to @CSCfi @SigridJuselius @SuomenAkatemia
#JAES #Ehrnrooth

[bioRxiv @biorxivpreprint]

Tunnel dynamics of quinone derivatives and its coupling to protein conformational rearrangements in respiratory complex I https://t.co/dGmf7zdjkk #bioRxiv

[Vivek Sharma @vivekvivsharma]

Check our new work on respiratory complex I. #MDsimulations by @JonathanLasham @OutiHaapanen

https://t.co/V7ZdbXh0Mk

@KumpulaScience @BIOTECH_UH @helsinkiuni @SigridJuselius @SuomenAkatemia #JAES #Ehrnrooth @CSCfi

[Vivek Sharma @vivekvivsharma]

@JonathanLasham giving talk @BIOTECH_UH seminar series

[Vivek Sharma @vivekvivsharma]

Check our latest collaboration work on #mitochondrial respiratory complex I https://t.co/pLS1ujS5Dh combining chemical biology with atomistic #MDsimulations. Simulations by Oleksii Zdorevskyi and @JonathanLasham. Thanks to colleagues at #Kyoto University Japan. @jbiolchem

[Vivek Sharma @vivekvivsharma]

High resolution structure and MD simulations of Mrp antiporter. Collaborative work with @YongChan_zzz @OutiHaapanen @MPIbp @goetheuni @IBC2_GU. Thanks to @helsinkiuni @KumpulaScience @BIOTECH_UH @SigridJuselius @SuomenAkatemia #Erkkofoundation #Ehrnrooth
https://t.co/igRkCEZiwr

[Max Planck Institute of Biophysics @MPIbp]

They determinated the high-resolution structure of a central component of the respiratory chain, mitochondrial complex I, and simulated its dynamics on the computer: https://t.co/Hd4G3DPqBI Congrats to @JanetVonck and co-workers from @goetheuni and @helsinkiuni 👏👏👏!

[Faculty of Science, University of Helsinki @KumpulaScience]

How energy is generated in the mitochondria of cells? High-resolution structure and atomistic #simulations allowed researchers to identify novel features in one of the key enzymes.
@vivekvivsharma @KumpulaPhysics
https://t.co/zAmMuXVIHt

[Vivek Sharma @vivekvivsharma]

Very happy to share our new collaborative work on respiratory complex I (https://t.co/bVVasy2yzr). @ScienceAdvances. Excellent #MDsimulation work by @JonathanLasham @Amina93364815 @OutiHaapanen and collaboration with @krparey @JanetVonck Werner Kühlbrandt and Volker Zickermann.