Josh Karelitz

[Altria Science @AltriaScience]

At this week’s 2026 CORESTA Congress, Altria’s Josh Karelitz presented his Abuse Liability Assessment of the Ploom® System, evaluating the heated tobacco system that Horizon Innovations, our joint venture with JT Group, plans to bring to U.S. adult nicotine consumers 21+.

Under the Tobacco Control Act, FDA must determine whether marketing a new tobacco product is "appropriate for the protection of the public health," considering the likelihood that adults who smoke will quit or switch and that those who do not use tobacco will start. An abuse liability assessment — how a product delivers nicotine, what subjective effects it produces, and how it is actually used — informs both, making it central to evaluating any new tobacco product for the U.S. market.

Across four relevant studies, Dr. Karelitz concludes the Abuse Liability of the Ploom® System is likely lower than combustible cigarettes, yet sufficient to support switching​​. #CORESTA2026 #TobaccoHarmReduction

[Altria Science @AltriaScience]

Science moves forward when we share, learn and collaborate. 🔬 At #CORESTA2026, we’re excited to exchange ideas and share our science, helping build the evidence behind smoke-free, reduced-risk options that adult nicotine consumers can feel confident choosing. It’s all part of our Vision of Moving Beyond Smoking™. #TobaccoHarmReduction

[Josh Karelitz @JoshKarelitz]

I signed up to run in this year's Pittsburgh Marathon to raise funds for an amazing non-profit organization, @ENVISIONBSports. Would you please join me in supporting Envision by making a donation using the link below? https://t.co/PqHBVV1d1T via @RaceRoster

[Altria Science @AltriaScience]

With a deep background in behavioral research and tobacco regulatory science, Josh Karelitz, PhD., applies his expertise to advance our Vision of Moving Beyond Smoking®.

As Principal Regulatory Scientist II in Regulatory Affairs at Altria Client Services, Josh leads abuse liability assessments and oversees the design and execution of studies that support applications submitted to the FDA for Altria’s portfolio of smoke-free products. Before joining Altria, Josh was a Postdoctoral Scholar in the Division of Cancer Control and Population Sciences at the University of Pittsburgh.

He has authored or co-authored more than fifty peer-reviewed publications and presented his findings at national and international scientific conferences.

Today at the 2025 CORESTA Product Science and Product Technology Conference, Josh will share findings and best practices from a literature review on actual use studies.

#CORESTA2025

[Altria Science @AltriaScience]

Today at the 7th Annual Next Generation Nicotine Delivery Conference, Josh Karelitz will present data on the harm reduction potential of the Ploom® System in the U.S. market.

The presentation will cover scientific evidence supporting the Ploom® System as Appropriate for the Protection of Public Health (APPH), comparative data on Harmful and Potentially Harmful Constituents (HPHCs) exposure versus combustible cigarettes, and the role of menthol-flavored heated tobacco sticks in helping adults who smoke make the switch.

[Josh Karelitz @JoshKarelitz]

@JonathanFoulds The IQOS 3.0 device used in this study is the version that received US FDA CTP marketing authorization in December 2020 (and sounds to be the same as what you used in your linked PK study).

[Altria Science @AltriaScience]

We can’t wait to share our research at the upcoming #TSRC Conference. Be sure to stop by Josh’s presentation on September 11th.

The presentation will be available for viewing at https://t.co/2cj9JcaZQc

[Altria Science @AltriaScience]

We’re looking forward to attending the 76th Tobacco Science Research Conference in Norfolk, VA. Register to hear our scientists talk about their recent work at https://t.co/aJwAp7S2b3.

Check out https://t.co/t5o7FMblWG to view their posters after the conference. #76tsrc

[Altria Science @AltriaScience]

Learn more about the development of reduced risk claims and their impact from our Population Science team next week at the Tobacco Science Research Conference. Register at https://t.co/mSeNFtn7CI and visit our website for updates at https://t.co/t5o7FMblWG

[Altria Science @AltriaScience]

Check out our poster "Pilot Study Investigating Rapid Visual Information Processing Task Assessment of Nicotine Delivery via Oral Nicotine Pouch Products" #cpdd22

Follow the link to view this poster: https://t.co/q6TcxRZQ1L

[SRNT @srntorg]

Thanks to Erin McClure, #SRNT2021 Program Chair, for the warm welcome, introducing participants to the meeting schedule and discussing how the 2021 all-virtual program will work. https://t.co/DWpcnJVY6b You can still register at https://t.co/6MQp55aKyd #nicotine #tobacco

[Josh Karelitz @JoshKarelitz]

Can the CO cutoff affect cessation outcomes in your smoking cessation study? Check out our new meta-analysis in @DrugAlcoholDep. @karen_cropsey @CaitlinWCleven2 @laurenrpacek
https://t.co/GH9vXqx0cL

[Josh Karelitz @JoshKarelitz]

Exited to share my latest article now available online

Acute subjective sensory perceptions predict relative reinforcing effects of smoked nicotine.

https://t.co/E3CwilXzfb