Journal of Pharmacogenomics & Pharmacoproteomics

[Italy MFA @ItalyMFA_int]

FM @Antonio_Tajani wraps up the conference “Together for the #SDG” @agritechit in #Naples. Firm commitment of 🇮🇹 authorities, academia & industry for food security&sustainability. Core priorities for the @UN Summit in #Rome in July and the Italian Presidency of the #G7 in 2024.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#mRNA can carry genetic information from genes to protein synthetic factories to guide #protein synthesis in cells. mRNA therapy is a treatment in which a specific mRNA is #synthesized and injected into a patient's body.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#Genes are instructions, written in DNA, for building protein molecules. Different people can have different versions of the same gene. Each version has a slightly different #DNA sequence. Some of these variants are common, and some are rare.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#Deoxyribonucleic acid is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries #genetic instructions for the development, functioning, growth and reproduction of all known organisms.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

Genetics is the scientific study of genes and heredityof how certain qualities or traits are passed from parents to offspring as a result of changes in #DNA sequence. A gene is a segment of DNA that contains instructions for building one or more molecules that help the body work.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

The molecular basis for #genes is deoxyribonucleic acid. #DNA is composed of deoxyribose a phosphate group, and a base There are four types of bases adenine,cytosine, guanine, and thymine the phosphates make hydrogen bonds with the sugars to make long phosphate sugar #backbones.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

In 1928, Frederick Griffith discovered the phenomenon of transformation dead #bacteria could transfer genetic material to "transform" other still-living bacteria, the Avery MacLeod McCarty experiment identified #DNA as the #molecule responsible for transformation.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#drug toxicity refers to the level of damage that a compound can cause to an organism. The toxic effects of a drug are dose-dependent and can affect an entire system as in the #CNS or a specific organ such as the #liver.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

The current #pandemic of COVID19 caused by #SARSCoV2 affects millions worldwide. As of November 26, 2020, worldwide confirmed infections are over 60 million in 191 countries/territorie.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

The sequences of these bases provide the instructions for building #molecules, most of which are #proteins . Researchers estimate that humans have about 20,000 #genes.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

In the most common type of sequencing used today, called sequencing by synthesis, DNA polymerase is used to generate a new strand of #DNA from a strand of interest. In the sequencing reaction, the #enzyme incorporates into the new DNA strand individual #nucleotides.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#pharmacology is a discipline that deals with mechanisms of action of naturally occurring mediators and #drugs at the level of the whole organism and the cell. Often confused with pharmacology, pharmacy is a separate discipline in the #Health sciences.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#pharmacology is a branch of medicine, biology, and pharmaceutical sciences concerned with medication action, where a #drug may be defined as any artificial, natural, or endogenous molecule which exerts a biochemical or physiological effect on the #cell , tissue, organism.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

The thick #mucus is also an ideal breeding ground for #bacteria and #fungi. #Cystic fibrosis (CF) is an inherited disorder that causes severe damage to the lungs, digestive system and other organs in the body.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#Genetic engineering, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of #cells, including the transfer of genes.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#Immunoassays can be applied in situations where you want to detect or separate molecules in a mixture. This assay can be used to identify the presence of #pathogens in #clinical samples or to measure the amount of target biomolecules.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#Genetics is the scientific study of genes and heredity of how certain qualities or traits are passed from parents to spring as a result of changes in #DNA sequence. A gene is a segment of DNA that contains instructions for building one or more #molecules that help the body work.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

A #drug or #substance that binds to a receptor inside a cell or on its surface and causes the same action as the substance that normally #binds to the #receptor.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

#pharmacogenomics is growing, and new approaches are under study in #clinical trials. will be used to develop tailored drugs to treat a wide range of health problems, including #Cardiovascular disease, Alzheimer disease, cancer & asthma.

[Journal of Pharmacogenomics & Pharmacoproteomics @JournalofPharm6]

Solid #pancreatictumors include PDAC, PET, gastrointestinal stromal tumor (GIST), #metastatic tumor, and #schwannoma. Excluded cystic pancreas tumors such as serous cystic neoplasm (SCN), mucinous cystic neoplasm (MCN).https://t.co/Lho821VvXr