#JAF is Director of Hematopathology, MGH, Prof of Pathology, Harvard, mother of Cindy and Debbie, native of New Orleans, now at home at Boston’s waterfront.
Pathologists! Join us for our annual Current Concepts in Surgical Pathology course, Oct 26-30. Live stream. 46 hours of CME available.
https://t.co/balw6cPVh3
Pathologists! Can you stand one more splenic B-cell lymphoma? In contrast to low grade splenic BCL, diffuse large BCL usually forms a large discrete mass. There are exceptions, e.g.,T cell/histiocyte rich large BCL may not form a discrete mass. #lymphoma#spleen#hematopathology
Note the diffuse infiltrate of small B cells in red pulp, atrophic/absent white pulp, & villous lymphocytes in blood. Good example of splenic diffuse red pulp small B-cell lymphoma.
Pathologists! Ready for another splenic lymphoma? Patient is 61 yo female with incidental lymphocytosis and eventually develops splenomegaly. What is your differential? #spleen#lymphoma#hematopathology
Pathologists! Ready for another splenic lymphoma? Patient is 61 yo female with incidental lymphocytosis and eventually develops splenomegaly. What is your differential? #spleen#lymphoma#hematopathology
Dx is splenic marginal zone lymphoma. Preferential white pulp involvement favors SMZL. IHC and genetic changes are classic. Must r/o MCL and rare follicular lymphoma. Pattern of splenic hilar nodes is typical. #lymphoma#spleen#hematopathology#splenicmarginalzonelymphoma
Pathologists! Are you ready for another splenic lymphoma? Patient had a lymphocytosis (ALC 9.2). The spleen was enormous, over 7 kg. What other work-up would you do? What’s your diagnosis? #spleen#lymphoma#hematopathology
Pathologists! Are you ready for another splenic lymphoma? Patient had a lymphocytosis (ALC 9.2). The spleen was enormous, over 7 kg. What other work-up would you do? What’s your diagnosis? #spleen#lymphoma#hematopathology