Julian Albarran Juarez

Mexican scientist working on atherosclerosis and smooth muscle cells at @aarhusuni ex: @cinvestav @unifreiburg @maxplanckpress

[Miguel Angel delPozo @madelpozo67]

Eskerrik asko to all participants!! See you soon!
Agur, beti arte edo hurrengora arte!
#AtheroConvergence @CaixaResearch @CICbiomaGUNE @CNIC_CARDIO

[Julian Albarran Juarez @JulianAljuz]

@madelpozo67 @SanchoLab @CNIC_CARDIO @CaixaResearch @AarhusUni @CaveoLab @ruizcabe @CICbiomaGUNE @lausotodosos @bio_miguelon @CaveWork @YaleVBTProgram @Yale @FundlaCaixa Thanks to @FundlaCaixa @CaixaResearch to make the #atheroconvergence meeting possible

[Miguel Angel delPozo @madelpozo67]

@SanchoLab @CNIC_CARDIO @CaixaResearch @AarhusUni @CaveoLab @ruizcabe @CICbiomaGUNE @lausotodosos @bio_miguelon @CaveWork @YaleVBTProgram @Yale @FundlaCaixa Julián Albarrán @AarhusUni gave a beautiful talk on #VSMC and #atherosclerosis
#Cholesterol upload vs #mechanical stretch approaches!!
#Atheroconvergence @CaixaResearch

[Nature Cardiovascular Research @NatureCVR]

Carramolino et al. show that #CholesterolLowering depletes #atherosclerotic lesions of smooth muscle cell-derived #fibromyocytes and #chondromyocytes. @CNIC_CARDIO, @AarhusUni, @ERC_Research, @novonordiskfond| https://t.co/OtmqriUhDD
👉https://t.co/fy0p3YSgml

[Ella Marushchenko @Ella_Maru]

@JulianAljuz @NatureCVR Considering the role of these cell types in plaque stability, could this research lead to more personalized approaches in treating atherosclerosis based on individual plaque composition?

[Diana Sharysh 🇺🇦 @DSharysh]

Our new study (https://t.co/5g0phFumyM) reveals that lowering cholesterol significantly can shrink atherosclerotic lesions by removing altered smooth muscle cells. Bright and colorful pictures are included!

[Hao Yin @HaoYin20]

ApoB #AntiSenseOligo + low-fat diet for 12 wks alleviates #VascularInflammation in established🐭#Atherosclerosis (AAV-PCSK9 D377Y)

#SmoothMuscleCell or #EndothelialCell reporter🐭

Several striking histopathologic features
1⃣Near complete absence of CD68+ Mφ!
2⃣60%⏬plaque area +proportional⏬lipid/collagen/necrosis
3⃣EC invagination & focal loss in regressing plaque😎 (#EndMT at sub-cap level)
4⃣⏫contractile #FibrousCap SMC; ⏬Fibromyocyte & Chondromyocyte (+⏬inflamm & matrix-remodeling transcripts)

NFκB-dependent lesional SMC plasticity

Also a nice example of how to use #SCENIC😁

@NatureCVR 2024 @JulianAljuz
https://t.co/PtIfKzMIAs

[Julian Albarran Juarez @JulianAljuz]

@HaoYin20 @NatureCVR Thanks

[Julian Albarran Juarez @JulianAljuz]

Small steps into the function of smooth muscle cells in atherosclerotic lesions @NatureCVR
https://t.co/TvXlTXCRze

[Julian Albarran Juarez @JulianAljuz]

@atvbahajournals Interesting

[Miguel Angel delPozo @madelpozo67]

Great PhD dissertation today by Rocío Muñiz in Jacob Bentzon´s lab @CNIC_CARDIO and great feedback by PhD committe @cmramirez15, @NMendezBarbero, JL Martín Ventura, V. Andrés & AP Jackson
A pleasure to collaborate in this work!
@Marta_pa16 @FidelBio_83 @bio_miguelon @CaveoLab

[Lori Shemek, PhD @LoriShemek]

Sugar is the sweet destroyer of cellular health and heart health. In fact, sugar promotes atherosclerosis, obesity, insulin resistance, diabetes, high blood cholesterol and hypertension. There is a staggering intake of sugar in the diet - unknowingly.

The average American ingests a whopping 156 pounds of added sugar every year. Many have no idea they are ingesting this much as it is added to almost every food available.

Many folks are purchasing what they assume to be ‘healthy’ foods when in fact, they are preventing optimal health and heart health. They buy fruited yogurts which can have more sugar than a candy bar; they bring home whole wheat bread – eating 2 slices of whole wheat bread raises your blood sugar more than eating 2 tablespoons of table sugar does and fruit juice enters the picture too – which is simply liquid sugar.

It is vital to read labels to check for added sugar.

[Laura Alonso @AlonsoLaura_]

Do you want to know more about the mechanisms of fibrous cap formation in atherosclerosis? Check out our latest review in @FrontCVMedicine

Smooth muscle cells rock 🤘

https://t.co/uaNP0Gg8Bs