Very glad I could present our work at the @TeloEMBO2024 ! Incredible week of sharing science, thank again to the organizers for the opportunity ! And to
@gaelle_pennarun & @Bertran45497785 for their support!
Our SPY™ probes in action for #FluorescenceFriday!
This is a live 2 cell mouse #embryo stained with SPY555-FastAct™ (grey) and SPY650-DNA (orange) going through synchronized #mitosis. For this movie ca 14'000 individual frames were recorded!🤩
Many thanks to Blake Hernandez (@loxstoplox) for providing the raw data.
#SPYprobes #LiveCell #Imaging
Wondering how chromosomes travel to gather at the spindle midplane in mitosis? Check out @KrunoVuk’s preprint “CENP-E initiates chromosome congression by opposing Aurora kinases to promote end-on MT attachments close to centrosomes”: https://t.co/LW95fim1Fi
Here is a tweetorial!
How does the structure of target DNA affect CRISPR/Cas9 off-target activity during gene editing? We show that negative DNA supercoiling dramatically reduces Cas9 specificity. Find out more here: https://t.co/PgX1XGjPRM
@MolecularCell@LUMICKS_nl@MRC_LMS@TheCrick@ucl
Registrations for the next DINGO meeting are open
See flyer attached and program and registration details at https://t.co/vA7yCaxFiE
8 short talks will be selected from abstract submissions.
Dead line for registration: 8th of October 2023 (11pm).
Please RT.
Check out our recent spotlight on a recent technology developed from @TeresaDavoli3 and colleagues to generate specific aneuploidy karyotypes https://t.co/uwW5E9G9oz
Exciting and inspiring scientific day today with my wonderful colleagues at the Journee IRCM! @anna_campalans opened it with a great talk and @jennysingh91 did an amazing job as chair of the session!
New publication of the laboratory Repair and Aging (LREV): « Close ties between the nuclear envelope and mammalian telomeres: give me shelter », Gaëlle Pennarun, Julien Picotto and Pascale Bertrand
Lien : https://t.co/lnlCnfXQl7
🥳
Such an amazing week at #EESAgeing interacting with so many great people, so gratefull I could share my work with my poster ! Winning the poster prize was the final touch of this incredible week, thank again #EMBO#EMBL, and @Bertran45497785 and @gaelle_pennarun for the support
We can't believe #EESAgeing is already over! We had a fantastic four days and hope everybody enjoyed the symposium and found it useful for their work 🧬⏳
📜🥇 Congrats to the three poster prize winners: Julien Picotto, Gayathiri Rajakumar, and Marjolein van Sluis 👏🏻
Have a safe travel back everyone!
Chromosomal instability (CIN) "remains one of the greatest unresolved genomic challenges in cancer treatment" and may become druggable
.https://t.co/n4XMLBv14I @ScienceMagazine by @Samuel_Bakhoum
#newscience alert! Chromosomal instability is a hallmark of #cancer, but how do cancer cells survive the resulting #DNAdamage ? This work suggests that the cells that survive might do so through upregulation of DNA repair genes. Check it out! https://t.co/VU9S0IE8T3