KPL ApS

At the Cutting-Edge of Protein Innovation.

[KPL ApS @KPL_ApS]

🔬 New bioRxiv preprint: Arg-C Zero, recombinant arginyl endopeptidase with >99% cleavage efficiency, proline-adjacent cleavage, Histone and labile PTMs analysis like ADP-ribosylation and comparable proteome depth to Trypsin.

https://t.co/cpWFzASQLG
#Proteomics #TeamMassSpec

[KPL ApS @KPL_ApS]

🇫🇮🔬 We're at #FinnProt2026 in Espoo, Finland!

Our CTO @HdezRollan is presenting a poster with the latest from our R&D pipeline 👀

Stop by to get an early look at what's next from KPL!

#Proteomics #MassSpectrometry #TeamMassSpec

[KPL ApS @KPL_ApS]

🚀 New #proteomics product: Trypsin/Lys-C Premium Mix

With the right formulation, you can add Lys-C and Trypsin together instead of sequentially.

🧪 One tube
⏱️One incubation
📉 Best-in-class missed cleavage rates
🌱 100% recombinant

https://t.co/XxqPY8CSuk

[KPL ApS @KPL_ApS]

Introducing Trypsin RMS - our third product is here.
Recombinant. Methylated. Sequencing-grade.
The robust Trypsin #proteomics labs need, without the batch variability of animal-derived alternatives.
Learn more: https://t.co/ZoanWdBGxi
#TeamMassSpec

[KPL ApS @KPL_ApS]

The following year, Kühne coined the term "enzyme" (from Greek "en zyme", in yeast).

Fun fact: many sources say "trypsin" comes from Greek for "rubbing" because Kühne ground up the pancreas. That's a myth. It actually comes from "thrýpto", meaning "I break".

[KPL ApS @KPL_ApS]

Trypsin is the workhorse of bottom-up proteomics. But when was it first discovered? 🤔🤔🤔

(Answer in the comments)

[KPL ApS @KPL_ApS]

The answer is 1876.
German physiologist Wilhelm Kühne discovered trypsin while working at the University of Heidelberg. He extracted it from pancreatic juice and showed it could digest proteins outside a living organism.

[KPL ApS @KPL_ApS]

New publication alert!📢
KPL collaborates w/ @JesperOlsenLab on the first systematic comparison of LysC enzymes for proteomics published in @JProteomeRes

A. lyticus LysC: >90% cleavage efficiency, >97% specificity

Read more: https://t.co/cTTYcHJ5Yn
#TeamMassSpec #proteomics

[KPL ApS @KPL_ApS]

Happy Holidays from KPL! 🎄

Our first full year: 2 product launches, lots of foundation building, and countless hours pushing #proteomics forward.

Our commitment: high quality, high performance, competitive prices. No compromises.

2026 is looking exciting - stay tuned! ✨

[Tanveer Batth @ucdmrt]

Really curious to get peoples experience with using SCIEX instruments for bottom up proteomics 🤔🤔 Remember you can post anonymously so please share the price as well ! 😅

[R/Proteomics @R_Proteomics]

A user is requesting input to decide between SCIEX or Thermo for proteomic MS instrument. Time for people to shine and share their experience.

https://t.co/xajeY8b2BF

#Proteomics #Teammassspec

[R/Proteomics @R_Proteomics]

#proteomics choose your fighter!

https://t.co/moBLrIgdRX

[KPL ApS @KPL_ApS]

🚀 Our very own @ucdmrt & @HdezRollan
will be at Nordic Conference in Mass Spectrometry & Proteomics 2025!

📅 Sept 1-3 | 📍Odense, Denmark 🔬Presenting the latest protease innovations!

Posters on Sept 1 and 2!

https://t.co/DKUMyM3nO8

#MSP2025 #Proteomics #TeamMassSpec

[Matthias Mann Lab @labs_mann]

To bead or not to bead? We evaluate five plasma proteomics workflows, finding bead-based methods enhance detection but show high susceptibility to cellular contamination bias. Strategies to optimize biomarker discovery in plasma proteomics.
https://t.co/Jkf2gIcY6w

[JesperOlsenLab @JesperOlsenLab]

🚨 Check out our new study on proteomic profiling in premetastatic colorectal cancer! Accross 412 tumors, we define molecular subtypes with distinct functional landscapes and revealed CAVIN1 as novel biomarkers for relapse risk.
https://t.co/w5lPUBMpuW

[ReSyn Biosciences @ReSyn_Bio]

Announcing a new product launch at @asmsnews 2025! What is in ReSyn Biosciences new kraft box? Let's make it a little more interesting... First person to correctly guess and post in the comments gets one for free!?!

[KPL ApS @KPL_ApS]

❄️ WINTER SALE ALERT! ❄️ Big savings on our products! Cozy deals that'll warm your heart and your wallet. 🔥 Shop now before these cool prices melt away! Find out more here:
https://t.co/Vo0hEiPYt5
https://t.co/xAqviEBfr8
#proteomics

[Oren Gottfried, MD @OGdukeneurosurg]

Antibodies

[atul deshmukh @atul_deshmukh1]

I am excited to share our latest publication in Science Advances!

We mapped the proteome of interstitial fluid across the leg in response to exercise, discovered immune cell derived peptide regulating muscle growth
@morten_hostrup
@Metabolcenter
@PRI_UCPH https://t.co/8vWhFPuxma

[JesperOlsenLab @JesperOlsenLab]

🚨 Our #singlecell article is out!
We describe the Chip-Tip label-free SCP workflow quantifying >5000 proteins in single HeLa cells. With high scalability, increased depth and throughput we can now envision large-scale LFQ-SCP biomedical studies!
https://t.co/iAHw51wBL5