Kalsotra Lab

Kalsotra Lab at Department of Biochemistry, University of Illinois, Urbana-Champaign. We investigate RNA processing and its role in health and disease.

[Jason Shepherd @JasonSynaptic]

It’s brutal in academia right now. A lot is out of our control, but it doesn’t cost anything to remember that there are humans behind papers and grants. Reviewers, program officials and funders can be more empathetic in the face of all the chaos in the US scientific enterprise.

[Nature Reviews Molecular Cell Biology @NatRevMCB]

New Online! Signal control during tissue regeneration in adult animals https://t.co/PXgIn9ZC4u

[Kalsotra Lab @KalsotraLab]

Dysregulated RNA splicing impairs regeneration in alcohol-associated liver disease | Nature Communications https://t.co/uZwFSyTzJH

[Hepatic Cell News @hepaticcellnews]

Drs. Anna Mae Diehl & Auinash Kalsotra led this study reporting that in alcohol-associated liver disease, alterations in the hepatic immune milieu prevent #hepatocytes from transitioning to proliferative progenitors.

👉 https://t.co/h87bo4wGgr

[Nutritional Sciences @DNSatUofI]

📰DNS Faculty in the News!

Dr. Auinash Kalsotra’s team shows how disrupted RNA splicing halts liver regeneration in alcohol-associated liver disease

🔗Read more: https://t.co/niRgGetkBt

#NutritionalSciences #DNSatUofI #interdisciplinary #research #DNSfaculty #LiverHealth

[cinesthetic. @TheCinesthetic]

What movie is 10/10, yet hardly anyone has heard of it?

[Kalsotra Lab @KalsotraLab]

Beautiful work, congrats Eddie!

[NatureStructMolBiol @NatureSMB]

New online! ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism https://t.co/JxDn3pT7lW

[Jake P. Baquiran @bokterium]

“To write for impact means to keep it as simple as possible.” Good read and very insightful.

https://t.co/5WIzWZjHqa

[Genes & Development @GenesDev]

In this study, Bangru et al. describe a regulatory switch that controls hepatocyte polyploidization and maturation through the activation of an RNA alternative splicing program that promotes cytokinesis failure and binucleation.

Learn more here:
➡️ https://t.co/24wdMQDSwE

[Stanford Medicine @StanfordMed]

A naturally occurring molecule identified by Stanford Medicine researchers appears similar to semaglutide — also known as Ozempic — in suppressing appetite and reducing body weight. https://t.co/9OXER1wKx4

[Kalsotra Lab @KalsotraLab]

🚨 New research from @KalsotraLab uncovers how ESRP2 drives hepatocyte maturation & polyploidization via the microRNA-122 axis—key for liver #regeneration & #disease resistance. Findings could boost efforts in #regenerative #medicine. @NIAAAnews @czbiohub
https://t.co/nfhERLzAv2

[Itai Yanai @ItaiYanai]

We have to stand up for science! Anyone who can join these rallies and believes that US science must be protected should come!

[Samuel Hume @DrSamuelBHume]

This is like AlphaFold, but for protein localisation rather than folding

It's a deep learning model that predicts a protein's subcellular compartment based on its amino acid sequence alone:

[Kalsotra Lab @KalsotraLab]

@MCB_Illinois covers new research from @KalsotraLab
https://t.co/tk16fsiNIf
@sushantbangru @KalsotraAuinash @DuncanWAndrew @DasDiptatanu @UllasChembazhi @SandipChorghade @_WaqarArif Russ Carstens, Jackie Chen, Nick Baker, JessicaDerham
@CancerCenterIL @UofIResearch @GenesDev @NIH

[Kalsotra Lab @KalsotraLab]

🚨 New research from @KalsotraLab uncovers how ESRP2 drives hepatocyte maturation & polyploidization via the microRNA-122 axis—key for liver #regeneration & #disease resistance. Findings could boost efforts in #regenerative #medicine. @NIAAAnews @czbiohub
https://t.co/nfhERLzAv2

[Jinwei Zhang Lab @jinweizhang]

Thank you @sarakosman @NatureSMB for featuring our two studies on #MALAT1 & #NEAT1 on the Nov cover! Led by @IliasSkeparnias we describe how #lncRNA partially mimic #tRNA structure for their maturation and #mascRNA #menRNA biogenesis. https://t.co/cK0MNirJMT

[elvis @omarsar0]

We live in incredible times.

[Molecular Cell @MolecularCell]

Evidence of RNA polymerase III recruitment and transcription at protein-coding gene promoters https://t.co/hdJ0qaLrAk

[Razvan Borza @rborza_]

AlphaFold can predict protein, DNA, or RNA complexes.. BUT is it easy to determine the reliable interactions?🤔

➡️ AlphaBridge will identify the most confident interactions, making your analysis easier!

🌐Try it here: https://t.co/VoUvfdDruD
👀Read more: https://t.co/wfEK74sSpo

[The RNA Society @RNASociety]

We are excited to announce that the RNA 2025 Annual Meeting website is live! #RNA25
https://t.co/ku0eHmxY06

Limited rooms are available at a special RNA 2025 rate to stay at the beautiful Town and Country Resort & Convention Center, so please book today!
https://t.co/BKtuHacSzG