Karginov Lab

The lab of Andrei Karginov in UIC's College of Medicine. We study #optogenetic and #chemogenetic regulation of kinases and phosphatases. Student-run account.

[Karginov Lab @KarginovLab]

Huge congratulations to Dr. Nic Leschinsky for defending his thesis last week! 🥳🎉

[Karginov Lab @KarginovLab]

A few weeks ago we took a lovely trip to Brookfield Zoo with the lab to see some fish, seals, and hippos.

[Karginov Lab @KarginovLab]

We're excited to be participating in the FASEB Protein Phosphatases Conference next week! If you're interested in talking all things Shp2, Barbara will be at poster 8b on Tuesday after her Flash Talk.

#PPCSRC22

[Karginov Lab @KarginovLab]

@regenknol @UICPharmacology @UICEngineering Congratulations!!

[Karginov Lab @KarginovLab]

@NabaLabUIC We went to Busse lake. Nice place.

[Karginov Lab @KarginovLab]

We had our Summer picnic this weekend and got to enjoy good company, good food, and great weather! ☀️

[Karginov Lab @KarginovLab]

@NabaLabUIC Those all sound incredibly fun! We reserved a grove in Busse Woods in Elk Grove Village for the day. Great lake access and lots of space to play lawn games.

[Journal of Cell Biology @JCellBiol]

Image shows combining parallel Shp2-mediated pathways to reconstruct cell morphodynamics. Fauser et al. @KarginovLab @UICPharmacology engineer a chemogenetic allosteric switch that allows for the regulation of the activity of protein tyrosine phosphatases https://t.co/RVVkRhSOFh

[Karginov Lab @KarginovLab]

Big congratulations to Dr. Jordan Fauser for her successful defense today! 🎉

[Karginov Lab @KarginovLab]

@NabaLabUIC Thank you so much, Dr. Naba!

[Karginov Lab @KarginovLab]

We are excited to present our latest work! Using an engineered allosteric switch, we regulate Shp2 phosphatase activity and dissect downstream dynamic signaling events. We then expanded this approach to regulate PTP1B and PTPPest https://t.co/qjKQmYW5Mo

[Karginov Lab @KarginovLab]

@regenknol Thank you so much, Dr. Shin!

[Karginov Lab @KarginovLab]

Thank you to all who made our recent publication possible!

#allostery #allosteric #regulation #chemogenetics #AcademicChatter #publication #AcademicTwitter

[Journal of Cell Biology @JCellBiol]

Jordan Fauser et al @KarginovLab @UICPharmacology engineer a chemogenetic allosteric switch that allows for the regulation of the activity of protein tyrosine phosphatases, as well as for their activation within specific protein complexes https://t.co/RVVkRhSOFh
#Biochemistry

[Karginov Lab @KarginovLab]

We were so excited to share our work on #optogenetic regulation of kinases at @FASEBorg #PKPSRC22. Thank you to the wonderful event organizers!

[InSiDESignalingDynamics @InSiDE_Seminar]

InSiDE 2022 starts in a week! Join us next Thursday June 9 at a special time (23:00 GMT) for what is sure to be a great seminar by Shinya Kuroda!

[Karginov Lab @KarginovLab]

We're excited to share our recently published review on allosteric regulation in @JMolBiol!

https://t.co/MeMNjaY4TG

#review #allostery #allosteric #regulation #AcademicTwitter #AcademicChatter #Publication

[InSiDESignalingDynamics @InSiDE_Seminar]

Save the date! InSiDE 2022 kicks off in June! Stay tuned for speaker lineup. To stay up-to-date, sign up on our website: https://t.co/4VbMdDl8nU