We're recruiting! Please spread the word. We're excited for someone to join our team with an interest in biochemistry and/or cell biology. The project will focus on cellular redox reactions that locally activate switches in protein complexes to drive signalling.
ONE WEEK LEFT
The Sharpe lab is looking for a postdoc or research assistant to help investigate how a specific mutation in the immune phosphatase CD45 affects its function in adaptive and innate immune responses
Full details: https://t.co/V7CNPSThk8
#ScienceJobs@Sharpe_Lab
Why bother keeping an inactive enzymatic domain?
Read the updated version of our preprint, now published @eLife!
We show that the pseudophosphatase (D2) domain of the receptor PTPRK controls substrate recruitment and specificity...🧵
https://t.co/1vLOXJ3onA
Please RT. PhD students funded by @UKRI_News face a cash crisis. They are working full-time, yet earning less than living wage. With the rising cost of living and increasing pressure to deliver high quality research that benefits society, something needs to change. THREAD (1/10)
Preprint alert! Another wonderful collaboration with @JanetDeaneLab@TheCIMR led by @_IainHay. Here we characterise the phosphorylation-independent recruitment of a substrate to a protein tyrosine phosphatase via a distal domain. #phosphatases (@CyertMartha it will be a thing!).
BLOG: PhD student Tiffany shares her placement experience learning a new technique to bring back to the Institute to understand more about wound healing and skin repair
Read more: https://t.co/Zy2qo53Ros
#CellSignalling#PhDLife
Congratulations @TalbotCooper , what an achievement!! 🤩
Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling https://t.co/0XsA3VZL1h
New paper out @MolecularCell ! 🎉 Check out our study on how MYC-driven #lymphoma hacks protein translation with the little help from #DDX3X and #DDX3Y RNA helicases.
https://t.co/igmG23mtvg
My first review was published today! It's on protein tyrosine phosphatases in cell adhesion...
https://t.co/XzbdknSY7r
Thanks to @Sharpe_Lab for all the help and support
Wishing all our followers a wonderful festive time and happy holidays. Our card showcases the winning entry to our 2020 Image Prize showing Katie Young's image of mouse organoids @Sharpe_Lab. Browse more stunning research images here: https://t.co/eqRIGaC1ba
Hayley Sharpe @Sharpe_Lab receives a 2020 Lister Research Prize Fellowship, recognising outstanding performance and potential in biomedical research. Congratulations Hayley! The funding will help develop a new area of research #phosphatases#signalling https://t.co/g7upyFQICc