Iain Hay

Postdoc in Williams Lab @MRC_LMB | Interested in structural biology of peripheral membrane signalling complexes | Prev. PhD @TheCIMR, via 🏴󠁧󠁢󠁳󠁣󠁴󠁿

[Hayley Sharpe @Sharpe_Lab]

We're recruiting! Please spread the word. We're excited for someone to join our team with an interest in biochemistry and/or cell biology. The project will focus on cellular redox reactions that locally activate switches in protein complexes to drive signalling.

[SPUN @spununderground]

"This morning it's all about what's underneath the land."

@BethanFManley was up at the crack of dawn to speak with @Davedoes_ for @BBCCambs about the mycorrhizal fungi beneath our feet and her work with @cisl_cambridge.

You can hear her at 1h40m https://t.co/Zms7RjxIH0

[Iain Hay @_IainHay]

@Sharpe_Lab @ERC_Research Congrats!! 🥳

[Iain Hay @_IainHay]

@AbellJonny @TheCIMR @wellcometrust @ProfKHarvey @JLS_Lab Congrats!! 🥳🥳

[@drsimoncook.bsky.social @DrSimonCook1]

Delighted that Hayley Sharpe @Sharpe_Lab has been awarded tenure. Hayley has proved to be a great colleague, citizen, mentor, supervisor and friend to many. But above all she is a brilliant scientist! Congratulations to my lab-mate! https://t.co/WxbwN1MVNW

[Iain Hay @_IainHay]

@HyperboIeva Ah yes, the classic

[Iain Hay @_IainHay]

Time to get phosphorylating people!

[Rohith Krishna @r_krishna3]

Very excited to share RoseTTAFold All-Atom and RFdiffusion All-Atom, methods for structure prediction and design of biomolecular assemblies! https://t.co/iG6rD0LHsi 1/n

[Rohith Krishna @r_krishna3]

Very excited to share RoseTTAFold All-Atom and RFdiffusion All-Atom, methods for structure prediction and design of biomolecular assemblies! https://t.co/iG6rD0LHsi 1/n

[Anna Howes @HowesAnna]

Delighted to share my first first-author paper in @ScienceAdvances 🥳We determined the structure of H2O2-activated ATM bound to p53 peptide substrate and suggest a mechanism for ATM activation by oxidative stress.🧵(1/11)
https://t.co/5sxL7nP1O4

[Iain Hay @_IainHay]

@MicrobiomDigest @DrPfAnnieDanny Shockingly (sarcasm), Prof Danny Annie's picture on both twitter and 'college' website is a stock image found by googling 'female professor' 🙃

[Iain Hay @_IainHay]

@GNRailUK Any updates on how I am going to get back to Cambridge?... No information at all at kings cross

[Iain Hay @_IainHay]

@ShannonMcKie1 @JanetDeaneLab 🥳🥳🥳🥳

[Janet Deane's Lab @JanetDeaneLab]

We're hiring two postdocs! We're a friendly, multidisciplinary team studying neurodegeneration and lipids.
https://t.co/ohXWAEV5xP

[Iain Hay @_IainHay]

Thank you again to my supervisors @Sharpe_Lab @JanetDeaneLab for all their support (I still remember pitching this in lab meeting..)
And thank you to great co-authors @katemulholland4 Tiff Lai @AtomicVirology for all their valuable contributions to a much-improved manuscript! 😃

[Iain Hay @_IainHay]

Why bother keeping an inactive enzymatic domain?
Read the updated version of our preprint, now published @eLife!
We show that the pseudophosphatase (D2) domain of the receptor PTPRK controls substrate recruitment and specificity...🧵
https://t.co/1vLOXJ3onA

[Iain Hay @_IainHay]

Key after-thoughts: Can the modular domains of receptor PTPs bind >1 substrate simultaneously?
Do PTPs have roles outside basic catalysis: As binding is mediated by a non-enzymatic domain, independent of substrate phosphorylation, can PTPs act as cellular scaffolds/signal hubs?