De-Sheng Ker

Structural Biologist @PellegriniLab, Biochem Department, Uni of Cambridge
Study protein-nucleic acid complexes.

[De-Sheng Ker @Ker_Ds]

Human primosome (Initiation state)
https://t.co/REVLsuYvwU

#MolecularNode

[De-Sheng Ker @Ker_Ds]

We got a 2.3 Å nucleosome structure from a single T25 flask (3mL culture). 🧬❄️
No liters of culture. No purification. Just nuclear extract + cryoEM grids.
Data available now on EMPIAR.

https://t.co/picndZIGYx

[De-Sheng Ker @Ker_Ds]

sedikit sedikit, lama lama jadi bukit

[Princeton Engineering @EPrinceton]

In an experiment reminiscent of the Transformers movies, @Princeton engineers created a type of material that can expand, assume new shapes, move and follow electromagnetic commands like a remotely controlled robot even though it lacks internal gears: https://t.co/IxDihhRHWH

[De-Sheng Ker @Ker_Ds]

Are we in risk of losing a future generation that struggles to express themselves without AI-assistance?

https://t.co/UgjZZNOY2L

[De-Sheng Ker @Ker_Ds]

@MSInordic #RTX50 + #msiVANGUARD

[De-Sheng Ker @Ker_Ds]

@NVIDIAStudio #GeForceRTX50

[De-Sheng Ker @Ker_Ds]

@NVIDIAGeForce Left 4 Dead 2! #GeForceGreats

[De-Sheng Ker @Ker_Ds]

Spotted Galaxy Flip in the wild for the first time.

[De-Sheng Ker @Ker_Ds]

Casio CRW-001-1JR.
Because why not?

[Chris H. Hill @chillzaa]

Are you:
1. Looking for a fully-funded PhD
2. Interested in virus genome replication
3. Excited about RNA-protein interactions
4. Keen to master techniques in structural biology and single molecule, fluorescence-based imaging (TIRF, FRET)

Then get in touch! And please RT

[De-Sheng Ker @Ker_Ds]

@NvidiaANZ @PcjunkieMods #GeF

[De-Sheng Ker @Ker_Ds]

@NVIDIAGeForce @PcjunkieMods #GeF

[De-Sheng Ker @Ker_Ds]

@NVIDIAGeForce @PcjunkieMods #GeForce

[De-Sheng Ker @Ker_Ds]

The week where wealth from dynamite invention is shared with some people from around the world.

[De-Sheng Ker @Ker_Ds]

Just only discover "--reuse_scratch" and "--keep_scratch" option in RELION.

[Our Future Health @ukfuturehealth]

This is how many people have signed up to #OurFutureHealth to help researchers find new ways to prevent, detect and treat diseases like dementia, cancer, diabetes, heart disease and stroke. Will you join our community and be part of the answer? https://t.co/J5YqTOqZ4d

[Robert Appleby @Rapp1eby]

Time for my yearly tweet…our paper has just been published in @MolecularCell ! A lovely collaboration and a great mix of cell biology, biochemistry, biophysics and #cryoEM showing a new role for human RAD51 in binding and protecting abasic DNA 🧬

https://t.co/jDWtjtv6Fg.

[De-Sheng Ker @Ker_Ds]

Citius, Altius, Fortius

[De-Sheng Ker @Ker_Ds]

Moral of the stories: test new batch of chemical, especially when they are used for cell growth.

I have experienced new batch of antibiotic that was too strong and keep killing our E.coli; new batch of IPTG that fail to induce protein expression

https://t.co/cQmYlPZkCy

[De-Sheng Ker @Ker_Ds]

Upset to learn some wealthy lab chuck away HisTrap/HiTrap column after single use to prevent cross contamination, and to save time, as "I ain't have time to wash it properly". Wouldn't it be better to just donate those column to less wealthy lab, rather going to landfill?