Mystery finally solved🧐! 10+ years of studies reveal accumulations of PDE11A4 in the aging brain to be droplets formed by Liquid–Liquid #PhaseSeparation (#LLPS). And they're surprisingly reversed by #PDE11A4 Inhibitors! Hot off the press: https://t.co/KJU47msH4h #DrugDiscovery
#scientist beware! @LeicaBio don't make 'em like they used to. Bought a Leica 3050s cryostat. First one sent was a 🍋. Took FOREVER for them to swap it out. Now, just a few months beyond the 1-year warranty, the replacement needs a $6K repair and Leica is making me pay in full?!
Our love for PDE11A continues! Sleep Quality- and Myopia-Linked PDE11A-Y727C Variant Impacts Neural Physiology by Reducing Catalytic Activity and Altering Subcellular Compartmentalization of the Enzyme https://t.co/HPQHh9hZ3t #mdpicells . Thanks to our collabs @Dr_Ana_P & more!
Lot's of cool 🧠🐭🧪stuff in this one led by former rock star grad student @KatyPilarzyk ! 👀Don't miss it! Another win for #girlpower with 80% of authors on this paper #womeninstem#womeninscience 👩🔬👨🔬👩🔬👩🔬👩🔬
Help us solve our latest mystery...what are PDE11A4 ghost axons??? 🧐To help us figure it out, read our latest pub "Conserved age-related increases in hippocampal PDE11A4 cause unexpected proteinopathies and cognitive decline of social associative memories https://t.co/N68Kb82G6E
Not cool @united. Long ago I booked a direct flight to Europe at an exorbitantly higher price for safety, with seats selected. now I find out you completely changed my itinerary without even notifying me. Different time, now connecting flight, & no seat assignment?! #baitnswitch
Ya gotta love when a journal claims they don't have formatting requirements for first submission, and then proceeds to reject the submission x3 for not following various formatting requirements. 😡
There are so many excellent @UMBC undergraduate students and Alum from diverse backgrounds performing research in my lab. The talent from the UMBC students is outstanding!
Pls RT: Super psyched! @JoeyCheers & @KickassKe11yLab are kicking off our wickedly interesting collaboration on the role of eCBs + PDEs in memory decline by recruiting a new Postdoc! Come for the cool science; stay for a School/Dept full of tools & support to help Fellows thrive!