Excited to share our work in @embojournal! https://t.co/27LqQ3hjBf
For decades, we’ve known that cells dismantle & rebuild the nuclear envelope in coordination with spindle poles.
But what is the relevance of this coordination? Follow this thread to find out 👇
Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress https://t.co/M1d5qkPZrt
Fat loss isn’t just about calories.
It’s about hormones, inflammation, and your nervous system.
Here is 10 proven tweaks that turn your body into a 24/7 fat-burning furnace🧵:
1. Cold Exposure
Mitochondria derived from apoptotic cells are effective stimulators of innate immune responses via NLRP3 inflammasome, leading to IL-1β production and neutrophil recruitment.
It is interesting to note that these same properties were lacking in mitochondria derived from healthy or necroptotic cells.