Kristijan Ramadan Laboratory

[Kristijan Ramadan Laboratory @Kramadan2]

This mechanism might regulate PARP inhibitor resistance: "Nucleophagy removes cytotoxic trapped PARP1".
Nat Cell Biol. 2026 Jun 2. doi: 10.1038/s41556-026-01961-5. Thanks to all co-authors and collaborators for this discovery; It is highly appreciated.

[Kristijan Ramadan Laboratory @Kramadan2]

Nucleophagy of DNA lesions also plays a role in the removal of trapped PARP1. Please check our manuscript posted on bioRxiv: https://t.co/q1TZD0QIcf
A great deal of credit for this work goes to our former PhD student, Gwennie Hoslett.

[Kristijan Ramadan Laboratory @Kramadan2]

@SPJacksonGroup @John_C_Fielden @jcornlab @Nature @ERC_Research Happy to see my ex-student is doing great. Well trained!

[Kristijan Ramadan Laboratory @Kramadan2]

How does the SPRTN protease recognise DNA-protein crosslinks? This has now been resolved in our manuscript: https://t.co/5BzgaG4NrW
The ubiquitin chains are the central regulators of SPRTN protease specificity and enzymatic activity towards DNA-protein crosslinks.

[Kristijan Ramadan Laboratory @Kramadan2]

@iDikic2 @CellCellPress @IBC2_GU @FCI_health @proxidrugs @dfg_public @sfb1177 @sfb1361 @SFB1531 @uni_mainz_eng @goetheuni Congrats, Ivan. Great work.

[Kristijan Ramadan Laboratory @Kramadan2]

We have a tenure-track professorship position in Cancer Biology focusing on genome stability, the ubiquitin system, and the animal/zebrafish cancer models: https://t.co/0S6pBCLbOB

[Kristijan Ramadan Laboratory @Kramadan2]

@EMBOevents on the DNA Damage Response in Cell Physiology and Diseases starts this evening with keynote speakers Titia de Lange (@RockefellerUniv) and KJ Patel(@ketanpatelimmo1). If you're interested in a professorship in Cancer Biology in Singapore, please find me at the event.

[Kristijan Ramadan Laboratory @Kramadan2]

@EMBOevents on the DNA Damage Response in Cell Physiology and Diseases starts this evening with keynote speakers Titia de Lange (@RockefellerUniv) and KJ Patel (@ketanpatelimmo1). If you're interested in a professorship in Cancer Biology in Singapore, please find me at the event.

[Kristijan Ramadan Laboratory @Kramadan2]

Congrats to our former PhD student, Dr Susan Kilgas, on her first authored paper as a post-doc in @ChowdhuryLab/@DanaFarberHarvard/ @harvardmed on the role of the long non-coding RNA NEAT1 in the regulation of 53BP1 function: https://t.co/PdOSULHyM1

[Kristijan Ramadan Laboratory @Kramadan2]

@stagljar @iDikic2 @ProfIgorRudan Nice to see a strong CROSci team together, and in Croatia.

[Kristijan Ramadan Laboratory @Kramadan2]

Study discovers new process for cells to repair DNA damage https://t.co/yXtRwOUugn

[Kristijan Ramadan Laboratory @Kramadan2]

Hrvatski znanstvenici otkrili proces kojim se poboljšava postojeća terapija za karcinom debelog crijeva https://t.co/UpmnW1p8at

[Kristijan Ramadan Laboratory @Kramadan2]

Oxford and NTU Singapore Study discovers new process for cells to repair DNA damage https://t.co/nXh2Ybj6wQ

[Kristijan Ramadan Laboratory @Kramadan2]

Congratulations to our DPhil student Pauline Lascaux, all our lab members, and collaborators worldwide @NTUsg @NTU_LKCMedicine @OxfordOncology @institutrb @VdangioE3lab @nunoraimundo on the role of nucleophagy in DNA repair. Please check: https://t.co/vgIe0n8SXE

[Kristijan Ramadan Laboratory @Kramadan2]

I am thrilled to announce that today, we launched a Cancer Discovery and Renegenartive Medicine Programme at LKCMedicine-NTU-Singapore: https://t.co/RWMGkXqU8p
We are recruiting new faculty members, but please feel free to reach out if you are interested in our research vision.

[Kristijan Ramadan Laboratory @Kramadan2]

DNA-PROTEIN CROSSLINKS in SINGAPORE
Several post-doctoral positions will be available in my new lab at LKCMedicine/NTU in Singapore. Please check out these links:
Senior Research Fellow:
https://t.co/LB2o0lDTiR
Research Fellow:
https://t.co/ly6RzfFkl6

[Kristijan Ramadan Laboratory @Kramadan2]

The Lee Kong Chian School of Medicine (LKCMedicine) is recruiting a junior principal investigator at the level of Assistant Professor in Cancer and Stem Cell Biology. Please check the call: https://t.co/d6f73un7hJ

[Kristijan Ramadan Laboratory @Kramadan2]

The Lee Kong Chian School of Medicine (LKCMedicine) is recruiting a junior principal investigator at the level of Assistant Professor in Cancer and Stem Cell Biology. Please check the call: https://t.co/d6f73un7hJ
A great opportunity to start an independent research career.

[Kristijan Ramadan Laboratory @Kramadan2]

We also want to thank our great collaborators for their contribution to this work; Nancy Maizels and Kostantin Kiianitsa.

[Kristijan Ramadan Laboratory @Kramadan2]

The lab is thrilled to see our Critical Reviews and Perspectives article on the isolation and detection of DNA-protein crosslinks: https://t.co/86VQRyYaYs .
We hope it will help scientists select the right DPC isolation assay to address their questions.