Arman

peptide manufacturing

[Derek Thompson @DKThomp]

This has quietly been a miracle month in medicine.

In the last 5 weeks we’ve got news on:

- retatrutide, the triple agonist GLP-1 from Lilly, basically melting fat and body-wide inflammation at record levels
- RevMed’s new pancreatic cancer drug showing unprecedented abilities to extend life
- small trial of a one-and-done PCSK9 gene editing therapy for slashing LDL cholesterol
- Mayo’s AI-assisted radiology showing vastly improved cancer detection
- this new therapy for metastatic solid tumors

This stuff is at varying levels of evidence. Retatrutide is ~100% on its way, other stuff needs more clinical trial data. But put it together and we’re maybe on the verge of majorly reducing the mortality of heart disease and cancer, the two leading causes of death in America.

[Andrej Karpathy @karpathy]

The hottest new programming language is English

[Zach Yadegari @zach_yadegari]

A wise mentor once taught me:

To learn product, study Silicon Valley

To learn marketing, study dropshippers

[Alex Fedotoff @FedotOff90]

Was at a cigar lounge in Miami last Thursday. 42-year-old two stools over starts telling me about his ecom brand. Eye strain supplement for office workers 35-55. $890K/month. Single product.

Asked him about his top-performing ad. He pulled it up on his phone.

The ad opens with a desk lamp slowly illuminating an unblinking, bloodshot eye. No music. Just the sound of a keyboard. Five seconds of dead silence. Then a voiceover: "Your eyes have been open for 11 hours today. You blinked 4,000 fewer times than they're built for."

Looks like a horror movie poster. Feels deeply uncomfortable to watch.

He told me he tested 240+ creatives in the first 18 months. Clean product shots, lifestyle imagery, doctor authority figures, customer testimonials. Nothing scaled past $4K/day. The horror movie ad hit $13K/day in the first week and has been running for 7 months without fatigue. Went back and pulled his brand on GetHookd to see what else he was running.

The horror eye is still the dominant variant — 11 active versions of the same concept in his account, each one a different unblinking eye. He's not chasing fresh angles. He's compounding the one that works.

Most ecom entrepreneurs make ads they'd be proud to show their mom. He makes ads that make his customer feel seen.

[Arman @KrispyEth]

@ResponseTe15897 You guys are not doing shit, you’re supporting this host

[Arman @KrispyEth]

They lied about the reason they had to cut our stay short. They said “the owner of this property has decided to end their agreement for the home effective may 31 2026” but the same Airbnb company listed the same house for $16,000 a month the date after they’re removing us illegally

Please tweet @airbnb and help us raise awareness to take this company down

[Arman @KrispyEth]

Then after questioning why the property was suddenly relisted for dramatically more money after our forced checkout…

this was the response.

[Alex Becker 🍊🏆🥇 @ZssBecker]

The best form of biohacking. Literally THE most incredible nootropic and brain fixer...

Is reading chunky-thick fantasy books.

Sit down. Read about elves and dragons.

If you can do it for 2 hour a day your brain will turn into a sniper scope of focus.

[Arman @KrispyEth]

@Airbnb @AirbnbHelp @AirbnbPolicy
THIS IS AN URGENT MATTER AND A HUGE FLAW WITHIN YOUR ORGANIZATION

On April 24th I had booked an Airbnb for me and my family that includes children and 2 cats

We are 6 people

I booked the Airbnb from April 24th - July 24th

We had encountered many issues with our host and faced many challenges, I am travelling for work and my family is homeschooled so there are 4 people staying at home
For the entire day, it was hard to adjust because of all the issues we had, but we had finally settled after a hard first month, we bought our own furniture, hired our own cleaning team because the place was filthy and they provided 0 support.

Today I woke up from the host telling us we need to vacate the property in less that 7 days

You guys took the hosts side, even though we had an agreement from April 24th to July 24th, all our plans were set and settled for these dates

Our host decided they can just remove us and you guys have till now done nothing about this, our host lied to you stating that we were fine with this change and you guys believed their lies, and after I told you guys about these lies, you guys still did nothing.

My family and I have been Airbnb user for 10+ years and have booked 30+ places and it’s a shame that this is how you guys treat us.

We’re being kicked out and have no where to go and you guys are not providing any support for the next accommodation

My account email is [email protected]

Please push your support team

[Blake Burge @blakeaburge]

Major life cheat code: Don’t romanticize potential. Measure yourself by what you consistently do, not by what you believe you could do one day.

[Mike Futia @mikefutia]

Claude Code Can Now Watch ANY Video

Here's how to give Claude the ability to watch & analyze any video.

0:00 - Claude Code Can Now Watch Any Video
0:21 - Demo: Analyzing a Grüns UGC Ad
1:32 - Inside the Video Analyzer Skill Output
2:53 - Why Gemini API
3:41 - How to Install the Skill in Claude Code
5:11 - Demo: TikTok Self-Tanner Ad Analysis
7:14 - From Analysis to Hook Variations for Your Brand

[zack @zackpaid]

heads up. a full funnel breakdown that would run you $15k in consulting fees is sitting right here: