Kumar Saurabh Singh

Assistant professor @MaastrichtU Exploring mechanisms of interaction & coevolution in biotic systems using integrative -omics

[Kumar Saurabh Singh @Kumar_S_Singh]

Preprint alert 🌲🌲🌲
We are excited to share our work integrating metabolomics & transcriptomics to discover plant biosynthetic pathways. MEANtools uses resources like RetroRules & LOTUS to integrate reaction and structural knowledge. Additionally, implementing a GNN-based reaction likelihood score approach prioritizes anticipated reactions.

Congratulations to all the coauthors @marnixmedema @jjjvanderhooft @s_vanwees @elena_delpup Hernando and Olga.

🌱 Recent works by @MarnixMedema group & @vdHooft_CompMet worth checking out!

https://t.co/YBXNfp5axj
https://t.co/UDaHVIJbVq
https://t.co/eSzFehAO1n

#multiomics #Metabolomics #Transcriptomics #Bioinformatics #PlantScience #OpenScience #SystemsBiology

[bioRxiv Bioinfo @biorxiv_bioinfo]

MEANtools: multi-omics integration towards metabolite anticipation and biosynthetic pathway prediction https://t.co/anKkBmxGIR #biorxiv_bioinfo

[Marios Georgakis @MariosGeorgakis]

Perturbation atlases are unique resourcew for decoding causality in biological pathways within single cells.

👉This paper presents a tool (TRADE) that assesses transcriptome-wide differential expression effects of gene perturbations with a new —transcriptome-wide impact=TI

[Horticulture Research @Hortres]

Pomegranate cold tolerance unlocked! Genome assembly reveals 5.4-Mb inversion & PgNAC12-PgCBF1 interaction. #PomegranateGenomics #ColdTolerance @OxfordJournals
Details: https://t.co/1ocZTQOzNv

[Molecular Plant & Plant Communications @MPlantPCom]

A telomere-to-telomere genome assembly for greater yam (Dioscorea alata) #correspondence #PlantCommunications https://t.co/btKXSTUE4G

[TrendsPlantSci @TrendsPlantSci]

A metabolon at the heart of steroidal biosynthesis https://t.co/ujjojl9Cif #plantscience

[Molecular Plant & Plant Communications @MPlantPCom]

Insects manipulate plant immunity via a cross-kingdom small RNA effector #spotlight #MolecularPlant https://t.co/j6qZjlLG2O

[GigaScience @GigaScience]

An impressive allo-octoploid contribution to our T2T Series.

A telomere-to-telomere phased genome of an octoploid strawberry reveals a receptor kinase conferring anthracnose resistance https://t.co/PYaKuoeTnP

[Emma Mitchell 💙 @silverpebble]

It would be so so helpful if you could retweet my May botanical illustration & mental health workshop in my previous tweet if you have a few seconds. I've been unable to work since December due to a breakdown (not remotely proud of this) and I'm trying to get back on my feet so if you could RT it would help enormously. I so love teaching people how to draw & how it changes brain biochemistry resulting in better mental health 🌿

[The Plant Journal @ThePlantJournal]

𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐚𝐥 𝐀𝐝𝐯𝐚𝐧𝐜𝐞
Computational metabolomics reveals overlooked chemodiversity of alkaloid scaffolds in Piper fimbriulatum
📖 https://t.co/jTUthAGa8O
📝 Damiani, Smith et al @tomas_pluskal
🗺️ @IOCBPrague @CzechAcademy @CharlesUniPRG

[Molecular Plant & Plant Communications @MPlantPCom]

The near-complete genome assembly of pickling cucumber and its mutation library illuminate cucumber functional genomics and genetic improvement #correspondence #MolecularPlant https://t.co/1loOVraGbw

[Molecular Plant & Plant Communications @MPlantPCom]

Mobilizing Triticeae diversity from Genebanks to farmer’s field #spotlight #MolecularPlant https://t.co/wwP63moc5P

[Molecular Plant & Plant Communications @MPlantPCom]

Gapless genome assembly and pan-genome of Brassica juncea provide insights into seed quality improvement and environmental adaptation #correspondence #PlantCommunications https://t.co/goxMxw8u1M

[Plant Science @sci_plant]

Co-option and neofunctionalization of stomatal executors for defence against herbivores in Brassicales

https://t.co/6veU9Z4Dyo
♻️

[Nature Reviews Bioengineering @natrevbioeng]

Modelling and design of transcriptional enhancers https://t.co/AQLk6qP4UC

[Horticulture Research @Hortres]

Wild grape genome reveals resistance genes, aids grape breeding. #GrapeResistance @OxfordJournals
Details: https://t.co/9kCFXWV5J3

[Sophien Kamoun @KamounLab]

#MustRead 👇

Transposon-triggered epigenetic chromatin dynamics modulate EFR-related pathogen response @manavellalab https://t.co/fezGR6k8Sr

[antisense. @razoralign]

Sequencing by Expansion (SBX) — a novel, high-throughput single-molecule sequencing technology https://t.co/GJL406M4iq

[Horticulture Research @Hortres]

Grape genomes reveal resistance genes, aiding breeding. #GrapeResistanceGenes @OxfordJournals
Details: https://t.co/9kCFXWUxTv

[Plant Science @sci_plant]

Medicago2035: Genomes, functional genomics, and molecular breeding

https://t.co/fDDn0W0b3Z
♻️

[TrendsPlantSci @TrendsPlantSci]

February Issue. Read FREE: Decoding resilience: ecology, regulation, and evolution of biosynthetic gene clusters (see cover); The plant memory and communication of encounters;Auxin may help patients to fight cancer & much more https://t.co/w3hFl93B44
#plantscience

[Nature Plants @NaturePlants]

New Resource: "Transposon proliferation drives genome architecture and regulatory evolution in wild and domesticated peppers" https://t.co/dpGUhupbOd

11 genomes of wild and domesticated pepper: transposable elements have shaped the evolution of genome structure.