Kyle Mentkowski

Postdoctoral Research Fellow at MGH/Harvard Medical School, investigating the intersection of cardiology and immunology in CVD. PhD graduate from @UBuffalo

[Maarten Hulsmans @MaartenHulsmans]

Excited to announce our latest work in Nature Cardiovascular Research, where we explore how we can target disease-promoting macrophages to help treat atrial fibrillation! 🫀⚡️🔥

Read more 👉https://t.co/TA0dzYLlcT

#Cardioimmunology #AtrialFibrillation #Immunotherapy

[Ana Simon Chica @ANASIMONCHICA1]

I couldn’t be happier with the decision to join @MatthiasNahrend lab at Massachusetts General Hospital and @harvardmed. Thanks to the @EMBO Postdoctoral Fellowship for the support! More about electroimmunology to come! 🫀⚡️👩🏻‍🔬

[Nature Cardiovascular Research @NatureCVR]

Research | Yamazoe et al. show that B-cell derived autoantibodies contribute to the development of atrial fibrillation, suggesting that targeting the humoral immune response may represent a viable therapeutic approach.

https://t.co/Wn0PC1tYfA

https://t.co/bU4JfhLWtI

[Matthias Nahrendorf @MatthiasNahrend]

Fresh in @NatureCVR
👇
https://t.co/zSWTn16XFz

A work of ❤️‍🔥 by Masahiro & friends shows how autoantibodies lead to atrial fibrillation.

This has translational potential as B cell depletion is established clinically. Need to find out which patients make those bad antibodies!

[Matthias Nahrendorf @MatthiasNahrend]

Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia | Science https://t.co/FrQryxcsmX

[Kyle Mentkowski @KyleMentkowski]

Great catching up with the Lang Lab at AHA! 🫀

[MGH Cardiovascular Research Center @mghcvrc]

Congrats to our semifinalists for the #CVRC2024 retreat oral abstract prize, Greg Gipson @adamjohnsonmd @KyleMentkowskil and Rashmi Richa—Kyle with top honors! A bright future for these talented young scientists. Mentors: @MatthiasNahrend @MarkELindsay @Raj_MalhotraMD @bmprii

[Kyle Mentkowski @KyleMentkowski]

A new article on EV engineering from the Lang Lab is out now in FASEB! A huge thank you to Touba and Lisa who took this research across the finish line 🎉 Read more here: https://t.co/CoFuIk8ah3

[Matthias Nahrendorf @MatthiasNahrend]

Sharing the translational followup to Maarten's AF paper last year. We introduce a drug candidate for atrial fibrillation ❤️❤️‍🔥⚡️ Awesome team effort!

Therapeutic Spp1 silencing in TREM2+ cardiac macrophages suppresses atrial fibrillation https://t.co/Qtw00oLcpw

[Matthias Nahrendorf @MatthiasNahrend]

For a joint project with Peter Libby on myocarditis, we are looking for a postdoctoral fellow with immunology background. Please email me if interested❤️‍🔥

[Paccalet Alexandre @alexPaccalet]

🚨My PhD work is out in @JACCJournals !! Using a translational approach, we highlighted the importance of MCP-1 and IL-6 and their role in macrophage recruitment and polarization! 🫀
https://t.co/LKzeCrPE4d

[Eric Topol @EricTopol]

How severe Covid leads to myocarditis without virus in the heart: the role of activated heart macrophages
https://t.co/osW3Xe9sHo @JanaGrune @ChariteBerlin @MatthiasNahrend @MGH_RI and colleagues

[Kyle Mentkowski @KyleMentkowski]

Massive, international effort to update the basic guidelines on EV research. Congrats @KennethWWitwer, @IsevOrg, and all authors! Proud to have contributed to the #MISEVconsortium

[Kenneth W Witwer (he/him) @KennethWWitwer]

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches #MISEV #ExtracellularVesicles
https://t.co/XQf9xHLNYi

@IsevOrg @IsevComms @ISEV_Journals

[Kamila Naxerova @naxerova]

We have open postdoc positions in our lab at the @HMSGenetics department!

Are you interested in somatic evolution? Do you want to work in an exciting, collaborative environment at the heart of the HMS campus ? Enjoy a rich academic culture and friendly colleagues?

More 👇

[Kenneth W Witwer (he/him) @KennethWWitwer]

Look what's under the tree: #MISEV2023 has been accepted for publication! This third iteration of the international consensus guidelines on minimal information for studies of #ExtracellularVesicles is brought to you by @Joadwe @lodrisc1 @GoberdhanD & Clotilde Théry, plus the #ISEV board and the whole, amazing EV community!
What you can expect from the new #MISEV:
Nomenclature: communication of concepts and new info on #NVEPs (non-vesicular extracellular particles)
Collection and pre-processing. Pre-analytical variables for EV sources including bacteria, biofluids, tissue
EV separation and concentration
EV characterization
Technique-specific reporting for EV characterization
EV release and uptake
Functional studies
In vivo EV studies
@IsevOrg @IsevComms @ISEV_Journals
#JEV
@EditBuzas @cblenkie @doldivizio @tomdriedonks @erdbruegger @Exosome_UPLC_MS @hillandy @LenassiMetka @SusmitaSahooPhD @AnaTorrecilhas @SNEVresearch and many more

[Paccalet Alexandre @alexPaccalet]

🤔Wonder what’s going on in your bone marrow after MI ? 🫀🦴

Have a look at our new paper in @NatureCVR!

https://t.co/Pq3pP0tYkm

Perfect illustration of team work!

Special thanks to @MatthiasNahrend for this opportunity to close the chapter!

[Matthias Nahrendorf @MatthiasNahrend]

Meet the longest lasting project of the lab⏳

🦴 marrow fat cells provide local fuel for hematopoietic stem cells after MI 🔥

https://t.co/DYxnML5Pii

Very happy that it is now out in @NatureCVR ❤️

Thank you fellows and collaborators for hanging in there on this journey!

[Kamila Naxerova @naxerova]

We are of course hiring! If you are interested in somatic evolution (normal tissue evolution, carcinogenesis, metastasis development) *in humans*, please reach out. New lab website is on the way and only delayed by my personal slowness. Old website in bio still accurate though.

[Nina Kumowski @nkumowski]

Coordinating people and outfits for today’s big experiment! @KyleMentkowski @PabelSteffen @MaartenHulsmans @noor_M0MIN @MatthiasNahrend