New paper from @LHSanders14 & her team (+ escape bio collab.s) reports that the #Parkinsons-associated LRRK2-G2019S mutant expressed at endogenous levels is sufficient to cause mtDNA damage in vitro; Both selective & non-selective LRRK2 inhibitors rescue
https://t.co/MJTDRRKnYk
A #science conversation that is just fun to watch -
and really interesting that this #mtDNA damage marker seems specific to #parkinsons while being detectable in blood.
Great presentation by @LHSanders14 and moderation by @Dr_Behrouz
https://t.co/blsT8zVP21
27 Questions - a lively Q&A session during Vincere Bio's weekly Journal Club.
@DukeU associate professor @LHSanders14 discussed her recent publication of a blood based Parkinson's disease biomarker, video below:
https://t.co/uBZpMkt6Ca
With the development of a blood test for damaged mitochondrial DNA, @duke_neurology's @lhsanders14 and team are finding new ways to diagnose Parkinson's disease early on, and hopefully identify treatments to reverse damage 🧬🩸 #DukeBrainInTheNews https://t.co/950Fyj878F
Join FASEB for DNA Damage and Repair in the Brain on October 18. This informative FREE online conference on how DNA damage and dysfunctional DNA repair may contribute to neurodegenerative diseases. @LHSanders14
Reserve your spot: https://t.co/TGKj9zOhFX
So excited to share our efforts in developing a blood test for Parkinson's disease!
#Parkinsons@DukeHealth@DukeMedSchool
Science Translational Medicine
https://t.co/r1N4ugKU8o