Luke Dingwell

PhD, University of Toronto; MD Candidate, University of Toronto

[Luke Dingwell @LSDingwell]

I am extremely happy to share that our manuscript has been published in #Hypertension titled, "B-Cell Deficiency Lowers Blood Pressure in Mice". Please DM to receive the full-text: https://t.co/cvdSnm67iG. #immunology #bloodpressure #kidney #Bcells

[Luke Dingwell @LSDingwell]

@SarahADick Congratulations, Sarah!

[Luke Dingwell @LSDingwell]

@CircAHA #AHA21 #HF Live forum happening now for: B-Cell-Mediated Sodium and Water Retention Contributes to Heart Failure Pathogenesis #P1964. Come say hello, connect, and leave any comments or questions!

[Luke Dingwell @LSDingwell]

@mansoor_husain and @benoitbruneau close-out a wonderful and diverse @KeystoneSymp #KSheartfail - looking forward to next year! Have fun everyone at the 'Lite Bites' and the mixer!

[Luke Dingwell @LSDingwell]

An excellent way to conclude @KeystoneSymp #KSheartfail presentations, with short-talks from @m_alexanian, Kathryn N. Ivey, and @austinchsu.

[Luke Dingwell @LSDingwell]

Fantastic talks from Kenneth Walsh on the role of clonal hematopoiesis in heart failure, and from @CardioOncology on immune checkpoint inhibitor-associated cardiotoxicities at @KeystoneSymp #KSheartfail

[Luke Dingwell @LSDingwell]

@trogersresearch

[Luke Dingwell @LSDingwell]

Happy to share that my colleague, @DrAhsan6, from @mansoor_husain Lab, presented his recently published (Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α. https://t.co/EO3h8Jr2Nt) and new work at Keystone.

[Luke Dingwell @LSDingwell]

@trogersresearch

[Luke Dingwell @LSDingwell]

Excellent presentations from Lisa Mielniczuk on the role of metabolism in pulmonary hypertension and right HF, @mansoor_husain on GLP-1 [specifically, GLP-1 (28-36)] and SGLT2i in CVD and HF, and @FerhaanAhmad on SGLT1 in CVD and HF at @KeystoneSymp #KSheartfail

[Luke Dingwell @LSDingwell]

Fascinating first talk of Day-4, and the last day of @KeystoneSymp #KSheartfail, from @TravisHinson on a new functional assay to test the impact of heart failure-associated genetic variants.

[E Matthew Morris @EMatthewMorris2]

Trainee Bliss Chang in the @rosenzweig_a lab @harvardmed sharing data on the interaction of age and exercise in the investigation of the mechanisms of heart failure. #KSexercise #KSheartfail

[E Matthew Morris @EMatthewMorris2]

...and now Dr. Jane Reusch from @CUAnschutz is sharing her labs work on mechanisms of reduced exercise capacity in type 2 diabetes. #KSexercise #KSheartfail

[E Matthew Morris @EMatthewMorris2]

Up now, Dr. Craig Emter from @Mizzou sharing data on the molecular mechanisms of interval training mediated improvements in cardiac function outcomes in a unique model of heart failure.

[E Matthew Morris @EMatthewMorris2]

Dr. Anthony Rosenzweig (@rosenzweig_a) starts off the evening session @KeystoneSymp #KSheartfail #KSexercise, with data on using exercise-mediated cardiomyogenesis as a tool to investigate new targets in the treatment of heart failure.

[E Matthew Morris @EMatthewMorris2]

The evening session is about to begin. Dr. Lisa Mielniczuk, from the University of Ottawa will chair the combined session, 'Exercise as a Treatment for Heart Failure.' @KeystoneSymp #KSexercise #KSheartfail

[Luke Dingwell @LSDingwell]

@KeystoneSymp @trogersresearch

[Luke Dingwell @LSDingwell]

Stellar talks from Kory J. Lavine and
@SarahADick on the role of macrophage subsets in heart failure, @benoitbruneau on gene regulatory networks in heart development, and from Andy Yu on Activin-A in endothelial cell senescence and its potential role in HFpEF #KSheartfail

[Luke Dingwell @LSDingwell]

Very interesting and thought-provoking presentations on the pharmaceutical roadmap from Victor Shi, and on new mechanisms of cardiomyocyte proliferation from @HeshamS70605263 at @KeystoneSymp #KSheartfail!

[Luke Dingwell @LSDingwell]

Day-3 about to start with a presentation from Victor Shi from @Novartis! Looking forward to it. @KeystoneSymp #KSheartfail

[Luke Dingwell @LSDingwell]

After a fantastic ‘Short-Talk’ from @laypingong1 and poster session, we are all excited to see what Day-3 has in store! @KeystoneSymp #KSheartfail