Michiels lab

[Michiels lab @LabMichiels]

🩸 From RNA-limited samples to the identification relative abundance of RNA modifications in a short time - The EpiPlex assay, presented at #RNGS25 by Gudrun Stengel of Alida biosciences, makes use of proximity barcoding and engineered binders to specifically detect RNA mods. 🧬

[Michiels lab @LabMichiels]

Our conference stress melted away after an evening filled with a choco-lot of fun at the #RNGS25 social activity at @ChocolateNatio4.

[Michiels lab @LabMichiels]

"Plants don't have specialized immune cells, but individual plant cells can flexibly turn into immune hotspots" - 🌱
@nobolly presented at #RNGS25 on combining single cell multiome data & spatial transcriptomics to study the genetic regulation of plant-microbe interactions.🧬🦠

[Michiels lab @LabMichiels]

Nanopore sequencing enables detection of DNA methylation profiles! 🧬

Mathilde Geysens showcased a powerful approach to identify episignatures of developmental disorders, offering deeper insights into methylation patterns and paving the way for future diagnostics. #RNGS25

[Michiels lab @LabMichiels]

Great poster by @genewizeu showing all the complex multiomics info that can be gathered from a single patient sample.🧬They also explored the single cell transcriptome on FFPE tumor tissues & show that better insights in human health can be obtained from minimal samples. #RNGS25

[Michiels lab @LabMichiels]

At #RNGS25, Kirsten Bos took us back in time by looking into the ancient DNA of infectious diseases.🦠 Her talk highlights the importance of genomics to trace the evolution and spread of syphilis, revealing crucial insights to improve our understanding of contemporary diseases.

[Michiels lab @LabMichiels]

Nice overview of the @illumina technology roadmap by Jason Betley at #RNGS25. In his talk, he provided a great perspective on the different Illumina platforms and more specifically on their various innovative and easy-to-use sequencing assays. 🧬

[Michiels lab @LabMichiels]

"Biology is dynamic like a river, you cannot step into the same water twice."

Great talk on unlocking high dimensional biology using evolved next-generation sequencing by @MollyminHe of @ElemBio this morning at #RNGS25.

[Michiels lab @LabMichiels]

Fun & adventurous talk on microbial dark matter at #RNGS25. @jimmysaw presented on harnessing long-read sequencing to enable reconstruction of geothermal bacterial genomes. His groundbreaking work brings us one step closer to uncovering biological functions in early life on Earth

[Michiels lab @LabMichiels]

I am very excited to be reporting on the groundbreaking talks at #RNGS25, together with @vanshikabidhan & @Sara_Alidadiani.

Follow me on Bluesky (@michielslab.bsky.social), LinkedIn (Lieze Agten) and here on X to keep track of this revolutionizing conference! @VIBTrainConf

[Michiels lab @LabMichiels]

🚨The final deadline to register for #RNGS25 is this Wednesday, March 5th!🚨

Make sure to register - You don’t want to miss out on Prof. Thienpont (@bernthie)'s fascinating talk on improving patient care by using cell-free DNA methylome analysis. 🧬

https://t.co/fRS1ADEqJM

[Michiels lab @LabMichiels]

🚨Don’t miss #RNGS25!🚨

🧬Prof. Jimmy Saw, who contributed to the discovery of the fascinating Asgard archaea, will explore how long-read sequencing unlocks microbial dark matter in geothermal habitats.🦠

📆Early bird registration deadline is February 5!
https://t.co/fRS1ADDSUe

[Michiels lab @LabMichiels]

Proud to present our latest model of aggregation-induced dormancy, published in #NatureComms @LiselotDW

https://t.co/i4Vnd0oW2i

[Michiels lab @LabMichiels]

🧬Join the #RNGS25 conference in Antwerp from 19-21 March to hear more about the exciting work of Dr. Tatsuya Nobori (@nobolly) on the single-cell and spatial dissection of plant-microbe interactions. 🌱🦠

📆Abstract deadline approaching: 15 January📆
https://t.co/fRS1ADDSUe

[VIB @VIBLifeSciences]

🧥 Bacteria have a protective coat of lipopolysaccharides. New work by @LabMichiels, @LiselotDW, Wim Versées, and colleagues highlights the crucial role of the protein ObgE, which could lead to new treatments for infections. 👉 https://t.co/9oNmWKdlM1 @VIB_microbes @structbiolbxl

[Michiels lab @LabMichiels]

Thrilled to have contributed to @LiselotDW's exciting work on the role of ObgE in LPS synthesis

https://t.co/9co2rR21ku

[FEMS @FEMSmicro]

In this editor’s choice, Vercauteren et al. comprehensively reviews mechanism, implementation, potential, strengths and weaknesses of #CRISPR interference (#CRISPRi), a gene perturbation technique. #FEMSMicrobiolRev @LabMichiels
https://t.co/gfHJN8muZv

[Michiels lab @LabMichiels]

Check out our latest work on antibiotic resistance mechanisms in nontuberculous mycobacteria https://t.co/Yuc9SixhC8

[Michiels lab @LabMichiels]

Check out our latest review on CRISPR-based approaches for high-throughput genomics https://t.co/8wDL5aaKTI

[VIB-KU Leuven Center for Microbiology @VIB_microbes]

Throwback to our @VIB_microbes retreat with @RaesLab, @LabMichiels, @Masschelein_Lab, @SibylleVonesch and @KevinVerstrepen's team at the Antwerp Zoo!