What is the role of diffusion of enzymes/other constituents in the spreading of histone modifications? We simulated a model with diffusion and reaction of reader/writer enzymes to explain the spreading of histone modifications. https://t.co/ccPpior8zO (1/5)
Our work is out in @NatureComms. Read the paper if you want a quantitative description of chromatin polymer or plan to simulate chromatin. We answer some fundamental questions. Details below. @sangramjkadam @KiranKumari_@vinoth46m@DuttaShuvadip@mithunmittir (1/10)
Exciting work from our lab in @PLOSCompBiol on histone modification inheritance, post replication.
With collaboration with Prof.Sibiraj Pillai from the electrical department IIT Bombay. Congratulations @nitkal and @ranjithpa.
Our work, modeling the high fidelity inheritance of histone modifications post replication, using ideas from information theory, is published in PLOS computational biology. https://t.co/xjm7jXCMDM @ranjithpa
Interesting work from our lab alumnus @AdityaRanganat4 on RNA-binding protein condensates and emergence of fibrillar structures using coarse-grained simulations.
https://t.co/49OWDFjvt3
RNA-binding protein condensates exhibit a physical phenomenon called aging which results in a loss of dynamicity. We use coarse-grained simulations to show that droplets can access several structural states with distinct intra-condensate environments.
Congratulations Prof. Rohit Srivastava @rsr004 on winning the prestigious SS Bhatnagar Prize in medical sciences. Proud moment for all of us @BsbeIitb@iitbombay
Delighted to share the preprint of our collaborative work with @Afroze_AC @dnarepairlab at Simon's center @NCBStheory. Chech out the preprint showing the role of SMC protein RecN in the repair process during dsDNA breaks in bacteria.
Congratulations!!
We are happy for our lab alumna Jyotsana Parmar for receiving the DST Inspire faculty fellowship. @Jewelparmar@IndiaDST@ranjithpa
https://t.co/Vcjix65TaH
Our labmate @KiranKumari_ receiving PhD degree. Congratulations Kiran! It is great to see your avatar in convocation robe and receiving the degree! Proud of you! Cheers and best wishes! @BsbeIitb@iitbombay@iitbmonash