Spagnoli Lab

Developmental and stem cell biology lab. Understanding the control of cell identity and plasticity and how to use it in regenerative medecine @KCLstemcells

[Spagnoli Lab @LabSpagnoli]

So excited to share our new paper today @Nature

Truly interdisciplinary study: #computational modelling, #lineagetracing and #scRNASeq uncovers sustained plasticity in hepato-pancreato-biliary development (1/2)
https://t.co/lqo1yVSp5S
@LabSpagnoli @KCLstemcells @kingsmedicine

[Nature Reviews Gastroenterology & Hepatology @NatRevGastroHep]

Our SEPTEMBER ISSUE is live! Pancreatic development, γδ T cells in CRC and liver cancer, precision nutrition in IBD, SLD in Latin America, and much more!

https://t.co/A0Lzr99tTx

[Shukry J Habib @ShukryHabib_Lab]

PhD opportunity in Aging, Bioengineering & Regenerative Medicine 🧬

We are recruiting for a fully funded 3-year PhD position in beautiful Lausanne, Switzerland 🇨🇭

Applications will be reviewed ONLY through the official UNIL website: https://t.co/hJmlbzrS1T

[Development @Dev_journal]

📣 One week left to register for #HumanDev26.

We have teamed up with the @wellcometrust -funded consortium Human Developmental Biology Initiative (HDBI) to co-organise our 2026 Journal Meeting. Register by 24 July 2026. https://t.co/1wtKBxdggj.

[Aida Martinez-Sanchez Lab @AidaMartinezS]

Our Section is recruiting an Assistant Professor, have a look at the link and apply if you'd like to be our new colleague! https://t.co/GSMLF4Zl9u

[King's Faculty of Life Sciences & Medicine @kingsmedicine]

Congratulations to Professor Francesca Spagnoli from King's College London who has been elected as a member of EMBO – recognising her outstanding contributions to life sciences research.

Read more: https://t.co/AnSCs9WFsB

[Biomedicina BCN @the_prbb]

📣 New PRBB-CRG conference

📋 Mapping progenitor niche dynamics for regulation of cell fate
🗣️ Francesca Spagnoli (@LabSpagnoli) - @KCLstemcells

📆 May 22 - ⏰ 12:00
hosted by: @1jorgeferrer - @CRGenomica

📍 #PRBB Maria Skłodowska-Curie room

[Spagnoli Lab @LabSpagnoli]

🎇Great fun writing this #review with
#AlejoTorresCano, highly talented postdoc in @LabSpagnoli

🤔reflecting on the emergence of #pancreatic #lineages in the #embryo through the lens of #plasticity
@wellcometrust @kingsmedicine @BreakthroughT1D @DUK_research

[Nature Reviews Gastroenterology & Hepatology @NatRevGastroHep]

New online! Understanding development and cellular plasticity in the pancreas in health and disease https://t.co/JMEGEU4ydV

[Pancreatic Cell News @PancreaticCell]

Drs. Alejo Torres-Cano (@LabSpagnoli) and Francesca Spagnoli explore how cellular plasticity and microenvironmental interactions drive #PancreaticDevelopment, regeneration, and disease, with implications for therapies for diabetes and pancreatic cancer.

Read the #review in @NatRevGastroHep: https://t.co/ZloeWmZt4f

[Giulia Biffi @BiffiGiulia]

🎉 Very happy to have had the opportunity to contribute to this latest @DiseasePrimers #Review on #PancreaticCancer together with a number of great colleagues! @ednacukierman @EileenMOReilly @SaurLab @BarbaraGrnwald ...

Hope it is a useful read! 😊💜

https://t.co/Q6dZPdHClD

[richard white @whitefishlab]

My department at Oxford is recruiting junior faculty to the Ludwig Institute for Cancer Research. A collaborative and stimulating department, with great access to the breadth of the Oxford environment. The positions come with core funding and cutting edge technologies. If interested, apply here: https://t.co/R5Lah3bZB3

[biorxiv_devbio @biorxiv_devbio]

Mesodermal-niche interactions direct specification and differentiation of pancreatic islet cells in human multilineage organoids https://t.co/UrgWK9JjXG #biorxiv_devbio

[King's Faculty of Life Sciences & Medicine @kingsmedicine]

New research from Professor Francesca Spagnoli reveals how different cell types develop, assemble, and communicate to build a functioning pancreas.🧬

https://t.co/vHlaLUNhmt

Image credit: Alejo Torres-Cano et al. Sci. Adv. 11,eadx5791(2025). DOI: 10.1126/sciadv.adx5791

[Spagnoli Lab @LabSpagnoli]

🚨 here it is the #DashBoard accompanying our new paper (see 🧵 below)
➡️ https://t.co/JFPPD4a04Z

😃 have fun exploring the dataset & #spatial #maps 🗺️

👏 👏 Kudo to Sami (#SiwanartaMa) MSc Bioinformatics for building the #DashBoard !!

[Spagnoli Lab @LabSpagnoli]

🚨 Check out our new paper is now online in its final version!!!
🎉 👏 Congratulations
Alejo Torres-Cano, who led the study
+ past & current team @LabSpagnoli
+ collaborators #VigilanteLab
@kingsmedicine

➡️ https://t.co/6JnJbCz5mJ...

[Spagnoli Lab @LabSpagnoli]

Spatially organized cellular communities shape functional tissue architecture in the pancreas | Science Advances https://t.co/BIU4xiJ8I2

[Spagnoli Lab @LabSpagnoli]

Congrats Alejo Torres-Cano postdoc in the @LabSpagnoli @KCLstemcells

[Pancreatic Cell News @PancreaticCell]

🕰️ Alejo Torres-Cano and team at @KingsCollegeLon combine single-cell and spatial transcriptomics to map pancreatic cell populations across space and time, from embryonic development to adult homeostasis in mice.

@ScienceAdvances | https://t.co/DiSnKNbiea

[Spagnoli Lab @LabSpagnoli]

🙏🙏 all our fundings @EUCouncil @wellcometrust
@NC3Rs #FundaciónAlfonsoMartínEscudero #postdoc support
@KCLBMBioscience
@BT1DUK #T1DGrandChallenge @DiabetesUK for next step of these discoveries

[Spagnoli Lab @LabSpagnoli]

🚨 Check out our new paper is now online in its final version!!!
🎉 👏 Congratulations
Alejo Torres-Cano, who led the study
+ past & current team @LabSpagnoli
+ collaborators #VigilanteLab
@kingsmedicine

➡️ https://t.co/6JnJbCz5mJ...

[Spagnoli Lab @LabSpagnoli]

We built ‘maps’ 💻showing that pancreatic progenitors and nearby supporting cells form niches &
used #stemcells 🧫to recreate pancreatic niches in the lab 🧪 & study how human beta cells develop

🙏 the Editor #ScienceAdvances & reviewers for great insights and comments

[Cambridge University @Cambridge_Uni]

https://t.co/KZMpWzTePc