Saur Lab

Dieter Saur lab | pancreatic cancer & colorectal cancer research | @TranslaTUM/Klinikum rechts der Isar | account run by Saur lab members

[DKFZ @DKFZ]

We welcome @ChiaraFalcomata, who started her new position as junior research group leader at DKFZ today. Her research focuses on how pancreatic cancer evades the immune system and adapts to therapy, with the aim of restoring anti-tumor immunity and improving treatment responses.

[nature @Nature]

Nature research paper: A serpin–myeloid axis in pancreatic cancer heterogeneity and immune evasion

https://t.co/T80pABJD4Q

[Eric Topol @EricTopol]

Pulling out all the stops vs pancreatic cancer.
The recent FDA-approved, celebrated drug daraxonrasib, increased median survival by 6.5 months @RevMedicines
That's a positive step but clearly not enough. This new @Cancer_Cell paper lays out a path for more.
https://t.co/i3Kb8fEDzm

[Maximilian Schaefer @m_mschaefer]

Excited to share our story on how SERPINs orchestrate local immunosuppressive niches in PDAC. Now out @Nature !

Spearheaded by @ChiaraFalcomata

@Brown_lab1
@MiriamMerad
@IcahnMountSinai
@SinaiImmunol

https://t.co/zaX6wXUPzq

(1/n)

[Waggoner Lab @LabWaggoner]

Cancer-derived SERPINE1 and SERPINB2 are local spatial organizers of immune suppression @Nature @IcahnMountSinai @ChiaraFalcomata @SinaiImmunol
https://t.co/vigXj9tQSc

[Saur Lab @SaurLab]

@ChiaraFalcomata @Nature Congratulations Chiara! Great work!

[Chiara Falcomatà @ChiaraFalcomata]

Pancreatic tumors are highly heterogeneous and immunosuppressive. But is immune resistance imposed across the whole tumor - or built locally by distinct cancer-cell states?

I’m incredibly excited to share our new paper, now out in @Nature! 🎉

https://t.co/jtEUKKFrBu

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[Anirban Maitra @Aiims1742]

Amazing news today, culmination of years of research & clinical trials in #PancreaticCancer.
The @RevMedicines approval for Rasonque (Daraxonrasib) will open many doors, including other inhibitors in this space & combinations. @OncoAlert @KRASKickers
https://t.co/07rvyKVQpy

[Saur Lab @SaurLab]

Honored to receive an #ERC Advanced Grant! EvokePDAC will reveal how #PancreaticCancer evades immunity and combine myeloid reprogramming with RASi to trigger antitumor immunity. Thanks to our team & collaborators! PhD & postdoc positions available—apply! https://t.co/78YpB8QqCN

[Saur Lab @SaurLab]

🚀 Excited to share Cellpin for #SpatialTranscriptomics! Led by P. Putze & D. Lucarelli with @fabian_theis. Outperforms 6 methods for gene prediction, scales to atlas-size references, and boosts cell-state resolution in full-transcriptome Atera data. https://t.co/KjPWcwAALN

[Anirban Maitra @Aiims1742]

EMA fast tracks review of a medicine for metastatic #PancreaticCancer
The medicine, no surprise, is Daraxonrasib.
https://t.co/4TnaQ8gaXv

[Lesley Goodburn @lgoodbu]

@Aiims1742 @CR_UK @BristiBasu8 @BiffiGiulia @SaurLab @TaraMcKay20 @CRUKresearch It was such a great conference-so much that patients families Need to know about keen to help them understand what this might mean for them there is so much Hope for better outcomes for a better future #sethslegacy

[Anirban Maitra @Aiims1742]

The @CR_UK #PanConf26 was proof how much great science is happening in #PancreaticCancer in the UK & rest of Europe. Now is the time for greater international collaborations with our partners across the Atlantic. Really enjoyed my time in London!
Thanks to @BristiBasu8 for 📸

[Giulia Biffi @BiffiGiulia]

The inaugural #CRUK #PanConf26 may be over but I suspect it will not be the last one…😉

And this is thanks to all the people that made this happen, especially @TaraMcKay20, our 350+ attendees (>60% from outside the UK) and my wonderful co-organizers @Aiims1742 and @SaurLab!

[Anirban Maitra @Aiims1742]

Ready to start Day 2 of the inaugural @CR_UK #PancreaticCancer conference!
Thanks to co-organizers @BiffiGiulia & @SaurLab, and the @CRUKresearch team for putting this wonderful meeting together. The conference hashtag is #PanConf26
@TaraMcKay20 @lgoodbu

[Anirban Maitra @Aiims1742]

Wow! Standing room only!
Amazing to see the full house at the inaugural @CR_UK #PancreaticCancer meeting. @ciacobu delivering her keynote lecture. Thanks to all the attendees for their enthusiasm.
@BiffiGiulia @SaurLab @TaraMcKay20

[Giulia Biffi @BiffiGiulia]

🎉 Day 1 of the inaugural #CRUK #PancreaticCancer conference is here 🎉

Thank you to @Aiims1742 @SaurLab @TaraMcKay20 and our session chairs for help shaping a fantastic programme!

[Saur Lab @SaurLab]

@Aiims1742 @CR_UK @BiffiGiulia @TaraMcKay20 @Fil_Bednar @Pasca_Lab @timofran1 @ChiaraFalcomata @IamLinghua @claus_jorgensen Looking forward to see you and the tie in London!

[Anirban Maitra @Aiims1742]

The overall survival curves for Daraxonrasib in 2nd line advanced #PancreaticCancer leave no doubt how impactful this advance is for the field & for patients. Congratulations Brian Wolpin, @EileenMOReilly & @md_oberstein et al.
A seminal #ASCO26 plenary!
https://t.co/ub099PSsOq

[nature @Nature]

Catalogue entries for more than 100 antibodies sold by the research services and supply company Thermo Fisher Scientific contain images that have apparently been manipulated, according to a pair of science sleuths.

https://t.co/5rUUgxceoE