Taia Wang Laboratory @wanglaboratory.bsky.social

We study how antibody signaling regulates innate and adaptive immunity.

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

Adaptive immune regulation of innate immunity ✨ the paradigm has been innate immune regulation of adaptive immunity but the relationship is bidirectional. So much to discover and learn here.

https://t.co/MiNJLScZmD

[Jason Sheltzer @JSheltzer]

My lab at @Stanford is looking to hire postdocs for multiple projects on cancer biology and therapeutics. Our recent work has uncovered some truly remarkable mechanisms for cytotoxic small molecules and we're looking to build on this research. If interested, see below:

[Waggoner Lab @LabWaggoner]

Transient host-cell glycoengineering to reduce N-glycan trimming strengthens IgG-FcγRIIIa bond resilience under vascular flow forces and potentiates therapeutic antibody efficacy in lymphoma and melanoma models @ImmunityCP @LabTaia @Stanford @UWBioE
https://t.co/g20X3zMq6Q

[David Kung-Chun Chiu @chiukungchun]

Congratulations to Wang’s lab @LabTaia, and Bowie @Bowie0625 on this elegant and impactful work, showing that antibody efficacy is not just about affinity, but also the durability of IgG-FcyR interactions under physiological forces.

https://t.co/gvNendunVL

[Grayson Rodriguez, PhD @grayerodriguez]

I am honored to be named a RISE Scholar by @parkerici, joining a community of incredible and ambitious researchers transforming cancer immunotherapy!

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

@soundgmh @ImmunityCP @StanfordMed @HHMINEWS @niaidcivics Sure, there are several nice papers on this. Let me know if you want additional references.

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

Out today in @ImmunityCP! We define how sialylation of IgG Fc domains regulates NF-κB-driven responses in the lungs.

https://t.co/I1aAOi309B

@StanfordMed @HHMINEWS @niaidcivics

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

@soundgmh @ImmunityCP @StanfordMed @HHMINEWS @niaidcivics https://t.co/om20JlBtlX

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

@soundgmh @ImmunityCP @StanfordMed @HHMINEWS @niaidcivics Afucosylated and asialylated Fc glycoforms predict more severe COVID-19 and the reduced sialylation in severe COVID-19 likely has a functional role (as well as the increase in afucosylation). Likely a broad role in respiratory infections but this needs to be studied.

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

Congratulations 🌟 to our own Joe Gonzalez for winning the McDevitt Award at @stanfordimmuno for scientific excellence. Well deserved 🎉🎊 @jccGz

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

@GordanLauc The hypothesis is strong, that “glycans are essential for nearly all aspects of immunity”, that’s why we do the work that we do. But there is so much to discover here and we are only at the tip of the iceberg.

[Gordan Lauc @GordanLauc]

Sialylated IgG protects against lung inflammation and severe influenza disease... Actually glycans are essential for nearly all aspects of immunity, but one has to look to see...
https://t.co/d2K4outRIO

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

@GordanLauc @Gops_GlycoIndia Yes.

[Congressman Robert Garcia @RepRobertGarcia]

RFK Jr. has no medical or scientific credentials and wants to gut the National Institutes of Health. And Marjorie Taylor Greene today cheered him on in our committee. This is outrageous and shameful.

[Nathan Lo @NathanLo3579]

Thank you to @TheLancetInfDis for featuring my research and early career in infectious diseases and public health. Check it out! https://t.co/fRBniNjHIy

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

yes! thanks so much to @brucegoldman for a great write-up on our recent study.

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

@ZivShulman @ImmunityCP @StanfordMed @HHMINEWS @niaidcivics Thanks!

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

@aaronmring @LabWaggoner Thanks, Aaron!

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

Thanks for highlighting our work @LabWaggoner! ✨

[Waggoner Lab @LabWaggoner]

Sialylated IgG induces expression of REST in alveolar macrophages via CD209, where REST dampens the responsiveness of macrophages to multiple NFκB stimuli and controls the inflammatory lung response to influenza viruses @ImmunityCP @LabTaia
https://t.co/UoJob5nh4l

[Michelle Monje 🟦 @michelle_monje]

#CARTcells for #DIPG #DMG clinical trial (1st arm) results are out today. Full Tweetorial coming, but first want to share the story of a patient whose #DIPG has disappeared for over 3 years. It is a milestone and moment of hope on a journey filled with so much grief.
“There’s a lot of loss that led to this research,” Drew’s dad said. “I hope those families know that this success is because of them.”
https://t.co/rNnHkL6pQR

[Taia Wang Laboratory @wanglaboratory.bsky.social @LabTaia]

@GuthmillerJenna @ImmunityCP @StanfordMed @HHMINEWS @niaidcivics Thanks!