Willcox LAB

γδ T cell immunology lab of Professor Ben Willcox at @ImmunologyUoB at the University of Birmingham @unibirmingham

[Willcox LAB @LabWillcox]

Very excited to share our study in @CellReports on the transcriptional basis of peripheral blood Vδ1+ T cell adaptive differentiation. https://t.co/Fp7bXsjti1

[Willcox LAB @LabWillcox]

Looking forward to the @BSI_TumourImm Tumour Microenvironment meeting in Birmingham today and tomorrow. Hope to catch up with old friends and colleagues there and hear about some exciting new science!

[Willcox LAB @LabWillcox]

@Jquintanalcala @UofG_SBOHVM @WCIPGLASGOW @LydiaBeckerIII @UoM_DIIIRM Congratulations Juan!

[Ben Willcox @ProfBenW]

Want to get up to speed with immune checkpoint blockade therapy for cancer ?
Register now for this online 13-hour CPD course ‘Understanding immune checkpoint blockade therapy: a pillar of modern cancer treatment’, from the University of Birmingham, UK, starting on Jan 24th, 2024.

[Willcox LAB @LabWillcox]

Pleased to be involved in this tour de force from @MohindarMK and the Herrmann lab!

[Mohindar Murugesh Karunakaran @MohindarMK]

I am happy to share our recent article at @NatureComms, presenting intricate mechanistic details on antigen - BTN interaction and BTN domains required for optimal Vg9Vd2 T cell activation. https://t.co/S2s8Ki3AqX

@LabWillcox
@WillcoxCarrie
@forum_gd
@Uni_WUE

[Willcox LAB @LabWillcox]

Thoroughly enjoyed our @ImmunologyUoB Away Day today. Fantastic posters and presentations by all including our very own @JulietGunn and PhD student Charlotte Begley, who won a prize for her work on splenic γδ T cells!

[Bruno Silva-Santos @BSilva_Santos]

Pleasure to write a meeting report on the 10th International Gamma-Delta T Cell Conference with @JuRiLibot @eberlmat @LabWillcox @ErinJAdams for @NatImmunol :)
It can be read here:
https://t.co/8tAI0kfZZD

[Willcox LAB @LabWillcox]

Congratulations Maria!

[WithersLab @LabWithers]

We have a post-doc position available focused on intestinal and cancer immunology. Ideal for PhD students soon to submit, who want to work with some cool in vivo models to better understand immune responses. Position advertised on BSI Jobs Board
https://t.co/aF4sGYds8s

[Willcox LAB @LabWillcox]

@CoffeltLab Congratulations Seth! Great news!

[Willcox LAB @LabWillcox]

@EdelblumLab Congrats to @MohindarMK for winning best presentation in the Ligands and Repertoires session!

[Willcox LAB @LabWillcox]

We’ve had a fabulous time at #gd2023! Thank you to @BSilva_Santos and Julie Ribot and team for putting on such a superb meeting. Enjoyed the science and catching up with friends and collaborators.

[Willcox LAB @LabWillcox]

@martindavey85 @EdelblumLab @UChiAdamsLab Yeah I recognise that. 🤣 Where are you Martin??

[Willcox LAB @LabWillcox]

On our way! See you in Lisbon @forum_gd

[Willcox LAB @LabWillcox]

Last few days to apply for a senior research technician job in our group! Join the team working on the best cells! https://t.co/kXqko4vHHP

[Cell Reports @CellReports]

Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1 https://t.co/tWJNjlRBw3

[Willcox LAB @LabWillcox]

Congratulations to @WillcoxCarrie and all collaborators not on Twitter. Link to Hermann lab study https://t.co/60ZQ6Odkmq

[Willcox LAB @LabWillcox]

New study on BTN3A1/BTN2A1/Vγ9Vδ2 TCR interactions out now in Cell Reports! @forum_gd We use mutagenesis, NMR and modelling to probe BTN2A1/3A1 IgV interactions. In a cool NMR expt we show that BTN2A1 IgV domain cannot bind simultaneously to BTN3A1 and TCR https://t.co/NtFpIgPeOR

[Willcox LAB @LabWillcox]

Our study complements a recent preprint by our collaborators in the Hermann lab showing a division of labour between BTN3A molecules in pAg recognition. Also interesting data coming soon from Zhang and Uldrich labs.

[Willcox LAB @LabWillcox]

New study on BTN3A1/BTN2A1/Vγ9Vδ2 TCR interactions out now in Cell Reports! @forum_gd We use mutagenesis, NMR and modelling to probe BTN2A1/3A1 IgV interactions. In a cool NMR expt we show that BTN2A1 IgV domain cannot bind simultaneously to BTN3A1 and TCR https://t.co/NtFpIgPeOR