ELambe

Lambe Lab at University of Toronto,
Optophysiology Neurodetectives

[ELambe @LambeLab]

CHRNA5 links chandelier cells to severity of amyloid pathology in aging and Alzheimer’s disease
https://t.co/qT3NpKDw5i @Transl_Psych
#rosmap investigation by Jonas Rybnicek aka @Knedlajz2 of @LambeLab with amazing collaborators @neuronJoy and @DanielFelsky (1/5)

[ELambe @LambeLab]

This afternoon at @physiologyuoft @uoftmedicine

[U of T Physiology @physiologyuoft]

THIS FRIDAY! Learn from the past with @TerenceKeel, explore the present with @KcD_PhD & @TheRealDrDukes, and help chart a diverse, inclusive future with keynote, @phdgprotein86. We can't wait to introduce our guests to the @uoftmedicine community! RSVP: https://t.co/1UNvuWMr3J

[ELambe @LambeLab]

Exciting to have had the opportunity to investigate key questions about human CHRNA5 #nicotinic receptors, especially in aging and #Alzheimers
@Transl_Psych paper link: https://t.co/qT3NpKDw5i

🐁Now back to mice to figure out the mechanism! @physiologyuoft @uoftmedicine

[ELambe @LambeLab]

CHRNA5 links chandelier cells to severity of amyloid pathology in aging and Alzheimer’s disease
https://t.co/qT3NpKDw5i @Transl_Psych
#rosmap investigation by Jonas Rybnicek aka @Knedlajz2 of @LambeLab with amazing collaborators @neuronJoy and @DanielFelsky (1/5)

[ELambe @LambeLab]

Thank you to our wonderful co-authors, collaborators, and @CIHR_IRSC. We gratefully acknowledge the #rosmap individuals and their families. (5/5)

[ELambe @LambeLab]

@Luna3150 @physiologyuoft used optophysiology to show that #CCK interneurons inhibit ventral hippocampus neurons tagged with #retrobead labelling from the nucleus accumbens. Great working with @jckimlab again!

[ELambe @LambeLab]

Vental hippocampal #CCK interneurons gate contextual reward memory https://t.co/NG1VLMoSZI
@iScience_CP

We braved the hippocampus because of a great collaboration 🙂 Elegant work by Robin Nguyen from @jckimlab and Sanghavy Sivakumaran aka @Luna3150 from @LambeLab

[Caleb Browne @JDCalebBrowne]

Had such a great time working on this with @jblaze8911, from post-talk idea to publication. So happy to see it out in @npp_journal! Congratulations @EricJNestler @AkbarianLab @VannaZachariou

[ELambe @LambeLab]

Great study on the lasting impacts of early life stress
https://t.co/t7bInYYSGA

[Derya Sargin @d_sargin]

Our paper now out in @BiologicalPsyc1 Early life stress induced disruption in serotonin networks and sex-dependent improvement on anxiety with mOFC serotonin fiber stimulation. Led by @RamkumarRaksha @moriah_edge https://t.co/BnXZ0xREPO

[ELambe @LambeLab]

@neuronJoy @CIHR_IRSC @DanielFelsky @ColinHawco @EtienneSibille Congratulations!!!

[Laura Medlock, PhD @laurmedlock]

Our latest #preprint on touch encoding in rodent mechanoreceptors is out now! 👈

🔗 https://t.co/IDl6pMCT5n

Many thanks to the huge, collaborative effort from the @PrescottLab that spans (most of) my PhD! 🥳(@Chris_Dedek @AHalawa99 @SickKidsNews @bme_uoft) (1/4)

[ELambe @LambeLab]

Ahem

[Alex Kwan 關進晞 @kwanalexc]

New work from my lab led by Hongli Wang and @heatherkortega. We studied ACh and NE signaling in the mouse medial frontal cortex, while the animal 🐭 plays a competitive game with a computer 🖥️.

https://t.co/KZ3voaDlJZ

[Toronto Dementia Research Alliance @TorontoDementia]

1/Today is #BellLetsTalk Day! Dr. @rajjitarek Executive Director of TDRA, et al, received a @Bell_LetsTalk/@BrainCanada grant to advance their research on enhancing theta burst stimulation for #depression.

Read parts 2 and 3 for updates on the work!

[Toronto Dementia Research Alliance @TorontoDementia]

2/Ex vivo work is progressing @LambeLab with a new calcium-imaging approach pioneered by @Sridevi292. Spacing episodes of stimuli ⚡️ appears more efficient. Next steps by @zolis_a.

[ELambe @LambeLab]

Thought-provoking afternoon @CureGRIN Roundtable. Patient/family perspective and cool research together!

Great to discuss impact of NMDA receptor loss and rescue: https://t.co/6QWh1TBWFx
Work @npp_journal by @sridevi292 @binko_mary @camielnik in @ajr937 & @LambeLab laboratories

[ELambe @LambeLab]

@ACNP meeting was always George's favourite
(science + social + sunshine)

[Shari Wiseman @sharilwiseman]

If you're watching the In Memoriam slides at #ACNP2023 and want to learn more about George Aghajanian, you can read the @NatureNeuro obituary from @LambeLab

https://t.co/lGAeVdLFlA

[ELambe @LambeLab]

This tree: "It's still Autumn for me!"
Gloriously sunny last day of November in #Toronto