Tamara Zudaire

#Pathologist 🔬 Always and forever learning. Hospital San Pedro. #CytoPath #HemePath #EndoPath

[Tamara Zudaire @LangerPath]

Ferruginous bodies in BAL.
Dumbbell-shaped, golden yellow to black with Pap, blue with Perls an golden yellow with H&E.
Happy to have seen them for the first time outside of the books! 😁
#cytopath #cytology

[C. Christofer Juhlin @DrJuhlin]

One of our brilliant residents showed me this case. Supraclavicular lymph node. No other clinical information at the moment.

Micropapillary to papillary structures, some mitoses, some mucin production.

(Short thread follows):

[Charlie Herndon @DrCycloPath]

🍤#Pancreas
#CytoQuiz🧐🧐🔬🔬

A) Pancreatic pseudocyst
B) Lymphoepithelial cyst
C) Serous cystadenoma
D) Mucinous cystic neoplasm

#Pathology #Cytology #PathTwitter
Clue in caption 🧐

[Charlie Herndon @DrCycloPath]

#CytoQuiz 🔬 #Pancreas🍤

A) Acinar Cell Carcinoma
B) Solid Pseudopapillary Neoplasm
C) Pancreatic Adenocarcinoma
D) Pancreatic Neuroendocrine tumor

#Pathology #Cytology
Clue in caption 🧐

[Kamran Mirza MD PhD - کامران مرزا @KMirza]

Asian male with enlarged node. FH with eosinophilic micro-abscesses. What's the IHC? #hemepath #pathelective #forfun

[Charlie Herndon @DrCycloPath]

🔬 #CytoQuiz
19-year-old with a firm nodule on the index finger.
A) Granular Cell Tumor
B) Epithelioid Sarcoma
C) Epithelioid Angiosarcoma
D) Clear Cell Sarcoma

[Charlie Herndon @DrCycloPath]

#CytoQuiz 🔬🧐
A) Myxoid Liposarcoma
B) Extraskeletal myxoid chondrosarcoma
C) Myxofibrosarcoma
D) Chordoma
#Pathology #Cytology Clue in caption 🧐

[Charlie Herndon @DrCycloPath]

#CytoQuiz #BreastPath🔬🧐
A) Ductal Carcinoma
B) Fat Necrosis
C) Phyllodes Tumor
D) Fibroadenoma

#Cytopath clue in caption 🧐

[Adriana Hogeboom @AdrianaHogeboom]

70 yo M no relevant PMH. Buccal mucosa ulcer biopsy (see H&E). Waiting on GMS. Do you buy cryptococcus? @ParasiteGal @LangerPath

[TigerHemePath @Tiger_heme]

BMB 41 yo male. All these cells are positive for CD3, CD5, CD2, CD7. In the pics you can see the CD4 and CD8. What is your diagnosis? What other stains would you like to see?

[Siba El Hussein, MD @SibaElHussein]

More on anaplastic large cell lymphoma (ALCL) mimickers:

Enteropathy associated T-cell lymphoma (EATL) may exhibit anaplastic morphology, with pronounced inflammatory background consisting of histiocytes, eosinophils, small lymphocytes, and plasma cells. Furthermore, EATLs with large cell or anaplastic morphology are often CD30+ and sometimes EMA+.

In the setting of a localized mass to the gastrointestinal tract and history of celiac disease, EATL would be on top of the differential, even if the morphology and strong CD30-positivity are reminiscent of ALCL.

However, in rare instances, where EATL with anaplastic morphology presents with involvement of extra-gastrointestinal organs, this could cause serious diagnostic challenges, as illustrated in this report @Histo_Journal➡️https://t.co/Xd36tXNFBb

#hemepath #pathology #pathX #pathtwitter #lymsm #MedEd #SoMe

[Siba El Hussein, MD @SibaElHussein]

Illustration of a case of Burkitt lymphoma in the intestine with characteristic variable/ patchy SOX11 expression pattern. SOX11 may come in handy in tricky cases when you need more evidence to push for Burkitt lymphoma vs other mimickers #hemepth #lmsm #pathtwitter #PathX #MedX

[Siba El Hussein, MD @SibaElHussein]

Unicentric Castleman disease-plasma cell variant:Preserved overall lymph node architecture and marked plasmacytosis in interfollicular areas,with a subset germinal centers showing regressive changes reminiscent of Castleman disease-hyaline vascular variant #Hemepath #HemepathMDA

[Kyle Bradley, MD @KyleBradleyMD]

What do you see in the interfollicular region of this lymph node?

What is the most likely etiology for this finding?

#hemepath

[TigerHemePath @Tiger_heme]

Axillary LN, 29 yo woman. What are the arrows pointing at?

[Siba El Hussein, MD @SibaElHussein]

Follicular lymphoma with BCL2 rearrangement by FISH & unusual overexpression of CCND1 by IHC (CD5 & SOX11 negative; CCND1 rearrangement negative by FISH). This rare finding has been reported previously➡️https://t.co/gtSjVY2wAD but is worth to be aware of #hemepath #lymsm #PathX

[Siba El Hussein, MD @SibaElHussein]

Relapsed classic Hodgkin lymphoma (CHL) with brighter PAX5 expression then typically accepted for CHL, and associated new emerging follicular lymphoma in the same lymph node biopsy (bottom right of Figure 1) #hemepath #lymsm #pathX #MedX #SoMe #Surgpath #MedTwitter #Pathtwitter

[Siba El Hussein, MD @SibaElHussein]

Follicular lymphoma with abundant extracellular eosinophilic material, mimicking amyloid deposition: An unsual variant to be aware of #hemepath #lymsm #pathtwitter #MedEd #SoMe

Check a similar but more prominent case by @sanamloghavi @BloodJournal➡️ https://t.co/FgGDXEZwZw

[Siba El Hussein, MD @SibaElHussein]

Large B-cell lymphoma involving the testicle with a germinal center-like phenotype (CD10+BCL6+MUM1-): May occur in < 10% of primary large B-cell lymphoma of the testis, however, it should raise the suspicion of disseminated systemic DLBCL #hemepath #lymsm #surgpath #Pathx #MedX

[Siba El Hussein, MD @SibaElHussein]

Primary large B-cell lymphoma of the CNS: Cyclin-D1 highlights endothelial cells in brain tissue, however its pattern of expression could be misinterpreted as positivity in neoplastic cells. Comparison to MUM1 & PAX5 is helpful to avoid this pitfall #hemepath #lymsm #PathX

[Syed Z. Ali @sza_jhcyto]

Salivary gland "Acinic Cell Carcinoma" may occasionally assumes a very "histiocytic" appearance on FNA, as nicely shown in this case. DD in such scenario includes - Mucoepidermoid CA, Secretory CA, Metastatic RCC and Benign cyst with macrophages.