Rheuma Doc

🩺UK based Rheumatologist & Internal Medicine | Education | Arsenal Fan 35 Years -🏆🔴⚪️ | Just living the Dream ☔️| طب الروماتيزم | 🎬 🏋️‍♂️♟️🎱

[Rheuma Doc @LastManStand85]

Steroids

2 mechanisms of action

1/ Genomic (activates @ 7.5mg-30mg Pred/day). Ceiling of saturation > 50mg. Limited additional anti-Inflammatory benefit beyond & ⬆️ Adverse

2/ NonGenomic. Act @ 100mg, Max sat 250-500mg & Less S/E as Shorter ⌛️

Less Is More! Great Slide 👇

[May Kazem, MD MHA FRCPC (She/her) @MayKazem]

#EULAR2026 #EULAR26 Factors associated with disease progression in #SystemicSclerosis
Single and multi variable analyses

[Rheuma Doc @LastManStand85]

The Management of Fatigue in Rheumatic diseases #Rheumatology #MedTwitter

[Rheuma Doc @LastManStand85]

Anifrolumab & #Sjogrens small RCT 👇

[TheDaoIndex @KDAO2011]

#Anifrolumab for #Sjogren. Small RCT study noted improved CRESS, cSTAR, ESSPRI, ESSDAI. No issues with safety, no change in histology score, but MxA expression reduced in ANI group #EULAR26 #Plenary @RheumNow

[Rheuma Doc @LastManStand85]

@Rakermoon @pokemondealsuk Yeah, we need ID verification!

[Rheuma Doc @LastManStand85]

@pokemondealsuk More likely to catch a unicorn than land one of these! 😄

[Rheuma Doc @LastManStand85]

The main causes of a raised CK 👇 [its not always myositis] #Rheumatology #MedTwiiter

[Javi del Cid @javidlcid]

Considering non-myopathic causes of elevated CK before initiating an extensive neuromuscular workup is essential for diagnostic efficiency, patient safety. Up to 1.3% of the general population exhibits asymptomatic or oligosymptomatic hyperCKemia, #eular2026 #london #autoimmune

[Md Yuzaiful Md Yusof @Yuz6Yusof]

#EULAR2026 OP0126 Long-term extension study up to 108 weeks: Ianalumab demonstrated sustained efficacy (change in ESSDAI) including those who switched from PBO to IAN in #Sjogren. IAN improved most domains apart from lungs, MSK & Haem - important to note @RheumNow #EULARBest

[Md Yuzaiful Md Yusof @Yuz6Yusof]

#EULAR2026 OP0125 It’s a case of “teamwork makes the dream work!” Instead of an index to capture heterogeneity in #Sjogren activity, the NECESSITY validated using data from 16 RCTs that a new composite tool, STAR has high sensitivity & specificity. Vital for use in RCTs @RheumNow

[Janet Pope @Janetbirdope]

You CAN identify #ILD in #rheumatic #diseases
🔜early
With a brief #questionnaire

Ask re
➡️dry cough
➡️dyspnea
➡️smoking

Not sensitive but high #specificity
Is it too late?
Maybe chest #auscultation at the #bases would be better?
🤷
#EULAR2026 ABST#POS0433
@RheumNow

[Rheuma Doc @LastManStand85]

Sad but true…

[The BMJ @bmj_latest]

Consultants in England are “quiet quitting” or looking to escape to Canada and Australia because they feel undervalued and disrespected, senior NHS doctors warn
https://t.co/l2v5SE5E62

https://t.co/QCVxEILYkl

[Antoni Chan MD (Prof) @synovialjoints]

At Week 52 with izokibep in #PsA PASI90: 63–69%; PASI100: 55–64%; MDA: 47–52%. The small-molecule format may enable deeper tissue penetration. Novel anti-IL-17 approach. Abstr#073 @RheumNow #EULAR2026 #Biologics

[NEJM @NEJM]

Presented at #EULAR2026:

In a phase 3 trial, obexelimab led to a lower risk of disease flares than placebo among patients with IgG4-related disease. Glucocorticoid use was lower and the incidence of remission was higher with obexelimab than with placebo. Full INDIGO trial results: https://t.co/Lynf6nmA9N

Editorial: Obexelimab and the Promise of Nondepleting B-Cell Therapy in IgG4-Related Disease https://t.co/BUQ7r8jVWz

@eular_org

[Rheuma Doc @LastManStand85]

@Only1tommo Our General, My Captain 🫡 See you next season legend!

[Rheuma Doc @LastManStand85]

@goldengaard Our champions, love it!

[Rheuma Doc @LastManStand85]

@EloyGarcia84 He met the final boss 😂

[Rheuma Doc @LastManStand85]

Neurobehcets 👇 #Rheumatology #MedTwitter

[Rheumatology update @aabdogafar]

Neuro-Behçet

[Rheuma Doc @LastManStand85]

@PokemonDealsTCG Well thats very underwhelming…

[Rheuma Doc @LastManStand85]

@DrNikhilMD Hydroxychloroquine!

[Rheuma Doc @LastManStand85]

@RaminNasibov The Greatest Ever Game!

[Rheuma Doc @LastManStand85]

@HandofArsenal Found you!!