Our study on tobacco smoke-induced mutagenesis in head & neck cancer (HNC) is out today in @NatureGenet ! https://t.co/05S9gWN12r 🧬🔥
We uncover the multiple ways tobacco and alcohol drive HNC development. A short thread 🧵⬇️
Congratulations to everyone who presented their work on the global stage at #AACR26. Each poster is a testament to the commitment and collaboration of exceptional teams, represented by:
💫 Shu Zhang - @Zoezs4 (eDyNAmiC), recipient of the AACR Scholar-in-Training Award, presented dynamic and defective repair of ecDNA
💫Annie Ellis (MATCHMAKERS), who presented Cancer Grand Challenges: partnership and purpose to maximise patient advocate involvement in collaborative preclinical research
💫Laura Torrens Fontanals -@LauraTorrensF (PROMINENT and Mutographs), who presented Deciphering the promotional determinants of oesophageal cancer
A fantastic display of collaboration and impact 👏
@AACR, @CR_UK, @NCICancerTrials
On International Day of Women and Girls in Science, we celebrate women who are redefining what’s possible in cancer research.
Across Cancer Grand Challenges, women researchers are reshaping how we understand cancer, how we collaborate across borders, and how science delivers for patients worldwide.
👉 Swipe to meet some of the future leaders in cancer research making a real impact @LauraTorrensF, @RuiyiTian, @KatieeYost, @PPCenteno22
#EveryVoiceInScience #WomenInSTEM #WomenScienceDay #GirlsInSTEM
Up to 4 in 10 cancer cases could be prevented says🆕global analysis from IARC & @WHO.
Study examines 30 preventable causes including #tobacco, #alcohol, high #BMI, physical inactivity, air pollution, UV radiation & for 1st time, 9 cancer-causing infections
https://t.co/Hh3XJLm3sW
And that’s a wrap for the #CancerGrandChallenges Future Leaders' Conference 2025!
This conference wasn’t just about sharing what’s been done—it was about igniting what comes next. The inspiration, the optimism, and the connections we witnessed will drive real progress in tackling some of the hardest questions in cancer #FLC25
It’s #WorldNoTobaccoDay🚭
#Tobacco causes over 20 types of #cancer and kills up to half of its users who don’t quit.
Tobacco and #nicotine industries use devious tactics to hook users into a cycle of addiction.
Don’t let them fool you: learn more at WHO https://t.co/yexj0cFswl
The #CancerGrandChallenges Mutographs team reveals how tobacco smoke damages DNA to drive different types of head and neck cancer 🧬
They also show that smoking combined with drinking alcohol can more than double the damaging effect on DNA ⤵️
https://t.co/g3btP2Baqr
Yesterday, #CancerGrandChallenges team Mutographs published a paper in @NatureGenet: The complexity of tobacco smoke-induced mutagenesis in head and neck cancer.
Here, first author @LauraTorrensF discusses the findings, her career journey & more.
Read 👇 https://t.co/2Uh1gBquJA
New study in @NatureGenet provides clearer understanding of how tobacco smoking🚬 contributes to development of #cancers of the head & neck, & further illuminates effect of combined exposure to tobacco smoke & alcohol🍺🍸🍷🥃.
https://t.co/vzfDT7MqOc
7/ Last but not least, a huge thanks to our fantastic team & collaborators from @IARCWHO, @sangerinstitute, @UCSD and many more who made this work possible! 💡🔬 Also, a huge thanks to @CancerGrand for fantastic support, as well as to the patients and their families ♥️
Our study on tobacco smoke-induced mutagenesis in head & neck cancer (HNC) is out today in @NatureGenet ! https://t.co/05S9gWN12r 🧬🔥
We uncover the multiple ways tobacco and alcohol drive HNC development. A short thread 🧵⬇️
6/ These findings deepen our understanding of how tobacco & alcohol contribute to HNC, reinforcing the urgent need for prevention efforts to reduce these exposures globally. 🚭
Last week we held our Future Leaders' conference, bringing together a key cohort of the #CancerGrandChallenges community: the early career researchers🌟
It was 3⃣ inspiring days of exceptional scientific talks & posters, keynotes, insights from patient advocates & networking.
🗣️The 41st #BarcelonaBioMed Conference reveals new avenues for #cancer prevention.
➕150 international scientists have discussed the factors that contribute to the risk of getting #cancer & their implication in the prevention of the disease.
🤝@FundacionBBVA
Read more here ➡️https://t.co/m2KlF0kTqP
IARC scientists & partners find 🆕 mutational signatures 🧬 in kidney tumours, indicating existence of multiple, geographically variable, & as-yet unidentified mutagenic exposures, potentially affecting many millions of people.
Results published in @Nature
https://t.co/4Isi3cFe7G