Dead Inside

[Dead Inside @Lecaptao]

@Vvallejos12 @neverlie @kirawontmiss Ah claro! Tinha de ser um pobre fudido de um argentino falando isso. Você não tem mais com se preocupar não? No seu país estão comendo carne de burro. Vocês literalmente estão virando uma Venezuela enquanto o Brasil é o mais rico e desenvolvido da América Latina.

[Dead Inside @Lecaptao]

@1eozinho01 Pq passaram a noite passada inteirinha comendo cu de curioso.

[REAL MIL GRAU @realmilgrauu]

Eu avisei que ele ia voltar kkkkkkkkkkkkkkk

DIOGO DEFANTE ESTÁ DE VOLTA!!!!

[Timdog @XboxTimdog]

Xbox Brazil is a special place. When Xbox lost its way there and didn’t come in on the pricing dilemma they messed up big time. What a passionate wonderful region of fans. Passionate like I

[Cássio Gabriel @CassioGabrielx]

🇧🇷 O Brasil é o país com...

🇯🇵 mais japoneses (e descendentes) fora do Japão.

🇮🇹 mais italianos (e descendentes) fora da Itália.

🇱🇧 mais libaneses (e árabes do Levante) fora do mundo árabe.

🇵🇹 a maior comunidade portuguesa fora de Portugal.

🌍 a maior população afrodescendente fora da África.

🇺🇦 um dos maiores polos de ucranianos fora da Ucrânia.

✡️ a 2ª maior comunidade judaica da América Latina.

🪕 Uma das maiores populações ciganas (Romani) do mundo.

🏹 Um dos países com maior diversidade indígena.

👨🏿‍🦰🧒🏻🧒🏾👩🏿‍🦱🧔🏼👨🏽‍🦲Maior miscigenação e diversidade cultural do mundo.

Somos a terra onde o mundo diverso se encontra e se torna um só. Não atoa, o passaporte brasileiro é um dos mais falsificados ao redor do mundo, pois literalmente qualquer um poderia ser um brasileiro.

A gente ama a Copa do Mundo e as Olimpíadas porque quando vemos pessoas de QUALQUER país do mundo, também nos vemos!

[Dead Inside @Lecaptao]

@Gamback12 @cyrille_juuf Eu preferia comer bosta do que ter nascido no Marrocos.

[Dead Inside @Lecaptao]

@Gamback12 @cyrille_juuf Kkkkkkk os caras moram no deserto, são árabes e pensam que são europeus.

[Dead Inside @Lecaptao]

@morrinvest @cyrille_juuf Não estamos não! Retardados tem em todo país e esses aí são minoria. 🖕🏻🖕🏻🖕🏻

[Felix @arrobafelixx]

Família cresceu ❤️

[Dead Inside @Lecaptao]

@cookiedobolo @Ricardo_Huee 🚨🚨🚨Betinha sem aura na festa do fim de semana detectado!!! 🚨🚨🚨

[Ricardo Hue @Ricardo_Huee]

QUANTOS ANOS??????

QUANTOS ANOS O ANCELOTTI FEZ???

[Harry Spoelstra @HarrySpoelstra]

Persistent Cerebral 18-FDG PET Changes in Patients With Long COVID Presenting With Fatigue and Post Exertional Malaise

🚨We already knew Long COVID brain damage could last 6 months.
Now this new PET scan study proves it’s still there at 2 YEARS and counting.
Hypometabolism hits the left sensorimotor cortex (movement + body sense), left superior parietal (spatial awareness + attention), and bilateral visual cortex (raw sight processing).
This is NOT just “tired.”
This is a broken sensory-motor command center.
Is this the start of a lifelong neurological disease?

➡️Mayo Clinic observational cohort study of 40 Long COVID patients (70% female, median age 53) from a specialized clinic who underwent brain 18F-FDG PET-CT scans 17–149 weeks (median 62 weeks) after SarsCoV2 infection,

➡️73% had predominant fatigue with post-exertional malaise (PEM),

➡️This group showed statistically significant cerebral hypometabolism vs. non-PEM patients in the left sensorimotor cortex (p=0.0253), left superior parietal cortex (p=0.0276), and bilateral primary visual cortex (p=0.0096 and 0.0016),

➡️Abnormalities persisted already up to ~2 years post-infection,

➡️Scans used pons-normalized Z-scores against age/gender-matched controls with common comorbidities included psychiatric, GI, and cardiovascular conditions,

➡️Caveat: No references to vaccination status and/or reinfections,

➡️Authors propose 18F-FDG PET-CT as a potential diagnostic and therapeutic biomarker for the fatigue/PEM phenotype of Long COVID.

‼️So, AGAIN, Long COVID fatigue and PEM have a demonstrable, persistent neurological signature! Cerebral hypometabolism, still detectable on PET scans up to two years later and hits the left sensorimotor cortex (movement + body sense), left superior parietal cortex (spatial awareness + attention), and bilateral primary visual cortex (raw sight processing).

This isn’t just “tired.”

It’s a broken sensory-motor command center.

😡Study proves LC is biologically real, not psychosomatic or any other stupid FND diagnosis.

Without urgent validation of this biomarker and targeted therapies, patients will continue to be dismissed despite objective brain damage!
#AvoidSars2 #AvoidReinfections #BrainDamage
https://t.co/OfoOlgDyt0

[Guenter GR @GrGuenter]

Die bisher beste Long Covid Studie wurde nun veröffentlicht, mit überraschenden Ergebnissen die neue Therapieansätze ermöglichen. Vereinfacht gesagt: Long Covid wird (in den untersuchten Bereichen) von Autoantikörpern im Blut verursacht, die dann sehr wichtige Teile des Gehirns angreifen und eigentlich alle Symptome erklärbar machen.

Wichtige Erkenntnis: Long Covid Patienten dürfen keinesfalls Blut spenden denn es scheint übertragbar zu sein über jene Autoantikörper im Blut!

Toller Artikel, verständlich geschrieben:
https://t.co/GDxqontAb1

[Hannah Davis @ahandvanish]

New: #LongCovid patients have alterations to the choroid plexus and reduced cerebral blood flow.

The alterations were associated with Alzheimer's markers, including GFAP and p-tau217.

https://t.co/qv9klVg7kI 1/

[Brain Inflammation Collaborative @BrainInflCollab]

A recent review proposes integrating POTS, ME/CFS, and Long COVID into the neuroimmunology subspecialty. Here is their compelling case.

\ Overlapping Drivers of Disease:
The authors outline several major overlapping pathophysiological mechanisms shared by POTS, ME/CFS, and Long COVID. This includes:
1. Autonomic Dysfunction (Dysautonomia)
2. Mitochondrial Dysfunction
3. Cerebral Hypoperfusion
4. Immune Dysregulation
5. Neuroinflammation
6. Autoimmunity

\ The Harm of Psychiatric Misdiagnoses:
For decades, patients have been wrongly labeled with "functional neurological disorder," anxiety, or somatization because routine tests often look normal.

\ A Call for Better Diagnostics:
Researchers and clinicians urgently need advanced tools such as:
- 7T MRIs
- Targeted PET scans
- Autoantibody and cytokine panels
- Comprehensive autonomic function testing

Routine tests are simply not enough.

\ The Authors’ Core Proposal:
Classify and treat POTS, ME/CFS, and Long COVID as neuroimmune disorders under the subspecialty of neuroimmunology.

This shift would:
• Improve clinical care
• Accelerate research
• Enable effective neurotherapeutics (including repurposed immunomodulatory and anti-inflammatory treatments)

Thanks, Dysautonomia Clinic, for the awesome paper!

#MECFS #POTS #LONGCOVID #PASC

Read more here: https://t.co/QD2SJuwQu3

[ME/CFS Science @mecfsskeptic]

1) A research collaboration including Theoharis Theoharides and Nancy Klimas reports dramatically elevated levels of MMP-9, an enzyme that components of the extracellular matrix.

They previously reported similar results in Long Covid but I have doubts about their reliability.

[$ @Ozymandias0_]

La vida desde que Asha Sharma se volvió CEO de XBOX.

[Xyber Feed @xyberfeed]

@asha_shar Was unfamiliar with your game 🐐

[El Último Huapango @Fut_hist_Soc]

Qué una mujer haya revivido a la gloria de xbox es lo más revolucionario, feminista y empoderado desde la posibilidad del voto.