Leicester Micro

News and research from microbial sciences at the University of Leicester. Microbiology, microbial genetics, and immunology.

[Chris @Chrisjrt]

🚨I did a science!🚨 I was lucky enough to help write a chapter on "Viruses" for this monograph on the lung microbiome along with @MarthaClokie and Will Flight. So have a look, there is some phagey-ness inside 😃

[@juliemorrissey @jam2620]

We have a BBSRC post doc position available https://t.co/U5fs3ITNsb following on from our characterisation of a novel copper resistance mechanism (CopB/X CopL) associated with the SCCmec in S. aureus USA300. 10.1111/1462-2920.14088

[Leicester Micro @Leicester_Micro]

Great opportunity to work on a multi-disciplinary PhD project here at Leicester #AMR #nanotechnology #phdchat

[LeMID @LeicesterMID]

Exciting PhD position on functionalised nanodiamonds for antimicrobial resistance application. With Prof Marco Oggioni see :

https://t.co/C4YeWoOBiu

[Dr Luisa MARTINEZ-POMARES-Laboratory @pomares_luisa]

Our manuscript looking at the contribution of the Alkylquinolone Quorum-Sensing system to the interaction of P. aeruginosa with Bronchial Epithelial Cells is out now. Good times!! Very proud of this work. @miguelcamarauk @UoNresearch @UoNLifeSci https://t.co/Z5aZoMjN7z

[Freya Harrison @friendlymicrobe]

Technician job in my lab! Looking for temp, p/t support to help my team to push a project to completion in Jan-Mar. Could be ideal for someone waiting for a PhD viva, or an existing p/t tech who wants some extra hours n the new year: https://t.co/5VfWidtJUL

[Dr Luisa MARTINEZ-POMARES-Laboratory @pomares_luisa]

PhD opportunity at Leicester-MRC Harwell-Nottingham. Look out for our project together with Chris Bayliss and Derek Hood on "Impact of hypermutable sequences on microbial elucitation and evasion of host immune responses". https://t.co/mRgSPW5hwU

[Giuseppe Ercoli @peppeercoli]

A new paper from our group describes a new #vaccine strategy against #pneumococcus. A genetically enginerened E. coli strain was used to both produce and conjugate carrier proteins and glycan. The formulated vaccine resulted to be protective both against pneumonia and meningitis.

[Leicester Micro @Leicester_Micro]

Great paper from @Hasanyesilkayaa at Leicester! #pneumococcus

[LeMID @LeicesterMID]

Pneumococcal galactose catabolism is controlled by multiple regulators acting on pyruvate formate lyase. https://t.co/Qw79rX29br

[Dr Hasan Yesilkaya @Hasanyesilkayaa]

The pneumococcal surface proteins PspA and PspC sequester host C4 binding protein to inactivate complement C4b on the bacterial surface https://t.co/oxvfjFp50J

[Geoghegan Lab @StaphLab]

Fantastic work from @MartaZapotoczna and our great collaborators at Newcastle, U Penn, @Infection_StAnd , @Leicester_Micro & Scottish MRSA Reference Lab #copper #MRSA

[Leicester Micro @Leicester_Micro]

Paper from the Bayliss group - 'PhasomeIt: an 'omics' approach to cataloguing the potential breadth of phase variation in the genus Campylobacter' out in #MGen @MicrobioSoc @Joewanford @Neisseriaspanin @JackAidley . Great collaboration with @sheppard_lab - https://t.co/mZwf68mnln

[Luke Green @Neisseriaspanin]

Now available as a full article! An investigation of how the phase variable tract of nadA could be used as a surrogate for prediction of Bexsero coverage, looks pretty good too #mrf #meningitis https://t.co/D4NHRmBHLG

[Leicester Micro @Leicester_Micro]

Great model from @peppeercoli and co, for the translation of pneumococcal research to a human-comparable model, and also for the reduction of exp animals in sepsis research! Out in #preprint in ALTEX @NC3Rs @jhucaat #sepsis #pneumococcus #pathogenesis

[Giuseppe Ercoli @peppeercoli]

If you are interested in bacterial infections and replacement of lab animal experimentation #3Rs, have a look at our innovative ex vivo model of bacterial sepsis using pig spleens retrieved from the abattoir @Joewanford @mr_oggioni #pneumococcus #sepsis https://t.co/3LnAJ1uw1C

[Leicester Micro @Leicester_Micro]

Great model from @peppeercoli and co, for the translation of pneumococcal research in mice to a human-like system, and also the reduction of exp animals in sepsis research! Out in #preprint in ALTEX - https://t.co/UE3hSdeP6f @NC3Rs
@jhucaat #sepsis #pneumococcus #pathogenesis

[Giuseppe Ercoli @peppeercoli]

If you are interested in bacterial infections and replacement of lab animal experimentation #3Rs, have a look at our innovative ex vivo model of bacterial sepsis using pig spleens retrieved from the abattoir @Joewanford @mr_oggioni #pneumococcus #sepsis https://t.co/3LnAJ1uw1C

[Leicester Micro @Leicester_Micro]

Just out - 'Integrase-Controlled Excision of Metal-Resistance Genomic Islands in Acinetobacter baumannii' from the Oggioni group! Congrats Zaaima and co #AMR https://t.co/PKX5Za21qV

[Dr Eva Tromans PhD @evatromans]

Congratulations to Zaaima for this great paper looking at how integrase activity excises much larger sections of DNA from genomic islands than previously thought! So pleased to have been able to contribute to this work https://t.co/kmMpDOsLgp

[Leicester Micro @Leicester_Micro]

Great work from the Bayliss group showing that phase variable gene expression can affect vaccine coverage estimates https://t.co/HwwqastWwK

[LeMID @LeicesterMID]

Phase Variation of NadA in Invasive Neisseria meningitidis Isolates Impacts on Coverage Estimates for 4C-MenB, a MenB vaccine. https://t.co/lq1rP1Rx5r

[Microbiology Society @MicrobioSoc]

Researchers at @Leicester_Micro and @M_R_F have developed a new test to find out if meningitis infection could have been prevented by vaccination: https://t.co/0RylYcBHYV

[Leicester Micro @Leicester_Micro]

'Research finds new way to determine protection of Men B vaccine against different strains' https://t.co/eyfI6i2KEh @UoLOutreach @LeicesterMID #vaccines #Meningitis

[Leicester Micro @Leicester_Micro]

New paper from the Bayliss lab out in @PLOSONE - 'Clustered intergenic region sequences as predictors of fHbp expression patterns and for assessing N. meningitidis strain coverage by meningococcal vaccines.' #vaccines #meningitis
https://t.co/K2vWeCt5MI