100K+ Americans are waiting for a kidney transplant. @USCStemCell researchers are growing lab-based kidney structures that mimic how real kidneys filter & function. https://t.co/0sEnBegpG6
By applying our understanding of kidney development, we were able to recapitulate some of the major renal organogenesis in vitro in our new human kidney progenitor assembloid! You can appreciate how the assembloid self-organizes in vitro!
@LiLab_Kidney https://t.co/H0u5kUsUQz
We have published in Nature Protocols a detailed protocol of our human nephron progenitor cell differentiation and expansion technology that we described last year in @CellStemCell. Hope this is helpful!
New Article! Expansion of human pluripotent stem cell–induced nephron progenitor cells (iNPCs) and the generation of nephron organoids from iNPCs https://t.co/skqWKgm4eW
Thank you @ScienceMagazine for highlighting our research progress in this news article.
Scientists make most authentic kidney replicas so far | Science | AAAS https://t.co/S1awdk0f6Z
In a Cell Stem Cell paper, a team led by Zhongwei Li @KeckSchool_USC combine kidney filtering & urine-concentrating components to make “assembloids,” lab-grown kidney structures for developing new therapies. @USCStemCell@LiLab_Kidney@CellPressNews https://t.co/MowICRrtu0
Our newest human kidney assembloid model features the formation of spatially-patterned human nephrons connected to a central collecting system. It exhibits a variety of kidney functions in vitro and in vivo. Online now in Cell Stem Cell: https://t.co/pOojmHNUnh
A @USCStemCell study, led by @LiLab_Kidney, improved the ability to cultivate nephron progenitor cells (NPCs), the cells that give rise to the kidney's filtration system. https://t.co/zR5Pq2HXC4
In our new Resource Article @CellStemCell we describe an expandable nephron progenitor cell-based kidney organoid platform with broad applications. Unlimited supply of human nephron progenitor cells makes us one step closer to making a synthetic kidney for transplantation.
Happy to share our new preprint: long-term clonal expansion of nephron progenitor cells (NPCs); genome-wide CRISPR screen in NPCs; nephron organoids with distal tubules; modeling nephron plasticity; rapid modeling and drug screening for PKD…https://t.co/VvUbRZnuq0
@AlexKoomz@USCStemCell@LindstromLab@AndyMcMahonLab @AnaNescolarde Thanks for visiting us, Alex and Ana! Inspired by your impressive research process in kidney development and organoid! See you next week at ASN!
Apply now for the USC Stem Cell postdoctoral program at https://t.co/gl8LjWihig. Enjoy terrific mentors, a generous stipend and 284+ days of golden California sunshine.