LiccardiLab

Cell death, Inflammation & Genome stability in Tissue & Cellular homeoastasis. Pi @Giammy_L @BCCologne #inflammation #celldeath #cellcycle #immunity #cancer

[LiccardiLab @LiccardiLab]

Fascinating!

[nature @Nature]

Female mouse embryos with a single letter change in their DNA develop male reproductive organs

https://t.co/1ouXzrhxWF

[ECDO @ECDOorg]

Registration is now open!
Join us in beautiful Favignana for an exciting meeting featuring a fantastic lineup of invited speakers.

We are pleased to offer opportunities for participants to present their work through short and flash talks

More info : https://t.co/AlB52aLd55

[Gianmaria Liccardi @Giammy_L]

ECDO IN FAVIGNANA 🌊
Save the date! 16-19 Sept 2026
Amazing program on Protein Degadation, Death Modalities, Metabolism, Precision Medicine.
Join us on a beautiful and historic island off the Sicilian coast, a place marked by the battles of the First Punic War.
Carthago delenda est.

[LiccardiLab @LiccardiLab]

SAVE THE DATE!

[ECDO @ECDOorg]

Join us at the 32nd ECDO Conference
“Death on the Beach: Cell Death & Disease” 🌊
📍 Favignana, Italy
📅 Sept 16–19, 2026

3 Nobel Laurates, 4 days of science, networking & Mediterranean vibes 🇮🇹

Don’t miss it!

#ECDO2026 #CellDeath #ScienceSA

https://t.co/6K39qkM7nK

[Gianmaria Liccardi @Giammy_L]

Fantastic work by the @Walczak_Lab . Congratulations to all authors for this amazing work now avaialble on Nature cell biology @NaturePortfolio. A new chapter for immune-signalling.
A must read!!!!

[LiccardiLab @LiccardiLab]

Fantastic work from the @Walczak_Lab on Nature Cell Biology @NaturePortfolio
Must read!

[Walczak Lab @Walczak_Lab]

Excited to share our new work uncovering a previously unknown mechanism identifying ANKIB1 as the E3 ligase that writes a critical new letter of the ubiquitin code central for immune signalling: K11-linked ubiquitin https://t.co/B9BQpsaVeV

[Walczak Lab @Walczak_Lab]

Excited to share our new work uncovering a previously unknown mechanism identifying ANKIB1 as the E3 ligase that writes a critical new letter of the ubiquitin code central for immune signalling: K11-linked ubiquitin https://t.co/B9BQpsaVeV

[LiccardiLab @LiccardiLab]

Congratulations to the @vonKarstedtLab on another excellent publication.

[Silvia von Karstedt @vonKarstedtLab]

Perfect way to end the year, read our new study on how absence of caspase 8 in #sclc promotes neuronal regrogramming and #metastasis via #necroptosis. @UniCologne @DTG_Cologne @CECAD_ @sfb1399 @UKKoeln
https://t.co/sPqJSpbtxE

[Gianmaria Liccardi @Giammy_L]

Reading the comments both under this post and under Nature’s obituary of Watson, it is impossible not to see how deeply ingrained sexism and abuse of power still are in science and beyond. Rosalind Franklin’s case was not only a tragedy of erasure, but an example of how authority and privilege once dictated who was allowed to define discovery itself. What is shocking is how many still defend the indefensible, revealing an almost atavistic belief in superiority and entitlement — the same mindset that enabled the abuse of power against Franklin in the first place

[Silvia von Karstedt @vonKarstedtLab]

A paper for #Halloween. Equally thrilled to have this work out in lightning speed with @Giammy_L ! #Ferroptosis #celldeath

[LiccardiLab @LiccardiLab]

Fantastic work by @vonKarstedtLab and @LiccardiLab
Ibrutinib sensitises to Ferroptosis
#dlbcl #ferroptosis #btk #ibrutinib

https://t.co/n6lCsnmFmP

[Gianmaria Liccardi @Giammy_L]

Thrilled to share our latest paper in Cell Death Discovery!
👉 https://t.co/tNwJoXX5Fc

Together with my fantastic co-senior and co-corresponding author @vonKarstedtLab , we uncovered that the BTK inhibitor ibrutinib has a previously unrecognized role in disrupting redox balance and priming DLBCL cells for ferroptosis.

We show that ibrutinibchemically scavenges glutathione (GSH) and represses GPX4 translation, thereby amplifying lipid ROS and triggering ferroptotic cell death. This defines ferroptosis as a mechanistic foundation for additive therapy in aggressive and apoptosis-resistant DLBCL.

This was a truly collaborative effort, driven by the exceptional first author Anuschka Langpape. Deep thanks also to all authors and our brilliant collaborators across Cologne for their creativity, hard work, and committment.
#Ferroptosis #DLBCL #CellDeath #RedoxBiology #BTK #Ibrutinib #CancerResearch #Oncology #TeamScience #CellDeathDiscovery

[Konstantinos Kelepouras @c_kelep]

🚀 Thrilled! Our Nature paper was highlighted in @MolecularCell! ✨
STING, known for innate immunity, regulates TNFR1 & ZBP1 necroptotic checkpoints, driving inflammatory cell death. Blocking necroptosis ameliorates SAVI pathology. 🙌 https://t.co/JheHN3SwlD
#STING #Necroptosis

[LiccardiLab @LiccardiLab]

Our research is featured on national news! Awareness and information are essential to empower innovation and translate scientific discoveries into real benefits for patients. 🧬🎥
#ScienceCommunication #Research #Innovation #CancerResearch

[Gianmaria Liccardi @Giammy_L]

I’m deeply grateful to @WDR_News for the opportunity to share my scientific journey and perspectives as part of the CANTAR (CANcer TARgeting) network, funded by Ministry of Culture and Science of the State of North Rhine-Westphalia (MKW NRW) @MKW_NRW.

Public communication is essential to connect research, innovation, and society — thank you for giving science a voice. 🎥🧬

#ScienceCommunication #Research #CANTAR #Innovation #NRW
@UKKoeln @BCCologne @CECAD_ @UniCologne @ItalyinGermany

[Gianmaria Liccardi @Giammy_L]

I’m deeply grateful to @WDR_News for the opportunity to share my scientific journey and perspectives as part of the CANTAR (CANcer TARgeting) network, funded by Ministry of Culture and Science of the State of North Rhine-Westphalia (MKW NRW) @MKW_NRW.

Public communication is essential to connect research, innovation, and society — thank you for giving science a voice. 🎥🧬

#ScienceCommunication #Research #CANTAR #Innovation #NRW
@UKKoeln @BCCologne @CECAD_ @UniCologne @ItalyinGermany

[Gianmaria Liccardi @Giammy_L]

🧬 New in Nature: Host cell Z-RNAs activate ZBP1 during virus infections https://t.co/60UjAOBA2H
Biggest congratulations to Sid Balachandran and his lab for yet another amazing piece of work on Z-RNA/ZBP1.
Turns out, it all starts with the DoTT.
#immunology #celldeath #ZBP1 #ZRNA

[Gianmaria Liccardi @Giammy_L]

Thank you @fattoquotidiano for covering our rcent work in Nature.
https://t.co/ZZPcLLr3nI

Full article: https://t.co/ojysOBje8q

[LiccardiLab @LiccardiLab]

@vasculitides @DiseasePrimers Check our recent paper on sting associated vasculopathy and the role of cell death inhibition as a valuable therapeutic treatmemt : https://t.co/Txc1dZdNvN

https://t.co/zomoiaOMa3

[Gianmaria Liccardi @Giammy_L]

The STING of death continues!
Thanks to @NatRevRheumatol (https://t.co/MgX76zHKU0) for highlighting our recent @Nature (https://t.co/mR4zXRjY1C) paper showcasing cell death as a therapeutic avenue in autoimmunity & autoinflammation, (SAVI syndrome).
(The image below is our own)
#immunity #celldeath #rheumatology #vasculitis #vasculopathy #lungdisease #pediatric #autoimmunity #infection #diseases #science

[LiccardiLab @LiccardiLab]

Fantastic team work! Lets keep the conversation going.

[Gianmaria Liccardi @Giammy_L]

The STING of death continues!
Thanks to @NatRevRheumatol (https://t.co/MgX76zHKU0) for highlighting our recent @Nature (https://t.co/mR4zXRjY1C) paper showcasing cell death as a therapeutic avenue in autoimmunity & autoinflammation, (SAVI syndrome).
(The image below is our own)
#immunity #celldeath #rheumatology #vasculitis #vasculopathy #lungdisease #pediatric #autoimmunity #infection #diseases #science

[Bambino Gesù @bambinogesu]

Quando le cellule si auto-distruggono: scoperto il meccanismo che scatena una #malattiarara infantile.

I risultati dello studio congiunto tra l'Ospedale e l'Università @UniCologne https://t.co/7SQekID3ac