Neurosurgeon whose life changed after weeklong coma (bacterial meningitis) - book Proof of Heaven was #2 nonfiction title on NYT Bestseller list for 2013.
Microtubules in cortical pyramidal soma and dendrites are interrupted, short, mixed polarity and antiparallel which is probably optimal for consciousness. These microtubules are also capped on both ends so they maintain their lattice mosaic structure to encode memory. They don’t disassemble for mitosis, don’t have ‘catastrophes’ where they suddenly disassemble, and don’t treadmill where they lose tubulins on one end and add on the other. So these microtubules don’t consume GTP or ATP and are stable for memory encoding and consciousness.
I’m not making a central mistake. You are.
First, consciousness cannot be measured or observed. For 130 years the standard surrogate test for whether an animal or human is sufficiently anesthetized (and therefore would not be conscious of a surgical stimulus) is whether they move in response to a stimulus like a tail clamp. That is how Meyer and Overton determined the potency of numerous anesthetic gases in numerous animals in 1897 and 1903. The average necessary concentration for each gas is called ‘MAC’ minimal alveolar concentration, the gas concentration at equilibrium where half the subjects move and half don’t. Each anesthetic has a different MAC but for each anesthetic MAC was/is the same for all animals. At equilibrium the same amount anesthetizes a salamander or a horse. Moreover MAC is additive. Half a MAC of sevoflurane and half a MAC of isoflurane is equivalent to one MAC of either, or any other anesthetic gas. And potency
(1/MAC) was proportional to each gas’s solubility in olive oil, approximating aromatic amino acid rings inside proteinsnwherexwuabtum stuff happens. So anesthesia (selective blockade of consciousness) is mediated by one target protein in all biology. Thats pretty astounding. Yes microtubules are in all animals and plants.
Which protein? From 1984 when Franks and Lieb showed direct anesthetic action on proteins for 24 years researchers looked at every membrane receptor and ion channel known. GABA_A and others bound anesthetics but inconsistently. Some anesthetics opened the channels, others closed them. Others didn’t bind to GABA receptors at all.
It’s true mutations to GABA receptors change MAC but many things change MAC like age, thyroid. other drugs etc. You can’t anesthetize animals or people with GABA agonist drugs no matter how much you give. Give huge doses of benzodiazepine and they
Sleep but still respond to stimuli.
Eger et al 2008 concluded no single membrane protein or group of membrane proteins could mediate anesthetic action. Period.
They didn’t consider microtubules to which all anesthetics bind but weakly.
Nick Franks observed anesthetic binding to GABA_A receptors ( for anesthetics which did bind) was a thousand times stronger than to tubulin/microtubules. But 1) there are a million times more tubulin per neuron than GABA receptors and weak binding is sufficient to disrupt a quantum state.
2) Anesthetics are chemically inert and only bind by quantum van der Waals forces.
Since 2008 genomic, proteomic, optogenetic and pharmacodynamics have all pointed to tubulin as the unitary target of anesthetic action. Period. There’s a good review in the anesthesia section of this paper. https://t.co/xghnEbhlUX
You asked for a conclusive result. There are many in there. But for the TWCF adversarial collaboration (which GNW and IIT both flunked (for $5 million) wd did the following ( for $100k).
For TWCF we predicted we would
1) demonstrate a quantum mechanism in microtubules at warm temperature
( we did)
2) show that quantum mechanism to be inhibited by anesthetics.
( we did)
https://t.co/ntbPdsODcK
It’s the only TWCF paper that reports positive results.
Final point. You keep saying I’m ignoring results supporting other theories of anesthesia or consciousness. Other than GABA receptor mutations which alter MAC (as do many other things)
what results am I ignoring?
There are no significant results supporting membrane proteins mediating anesthetic action or consciousness. Cartoon neurons don’t work. Correct me if I’m wrong.
Spiritual psychiatry is often misunderstood, so clarity matters.
Myth: It is pseudoscience or vague positivity. Reality: It is a clinically grounded approach that considers meaning, values, contemplative practice, and spiritual experience alongside evidence-based mental health care.
Myth: It replaces diagnosis, medication, or psychotherapy. Reality: It does not replace responsible clinical care; it adds discernment about how inner life, belief, and purpose can affect suffering and healing.
Myth: Every unusual experience is "spiritual." Reality: Good care requires careful assessment, ethics, and rigor to distinguish spiritual questions from symptoms that need treatment.
At its best, spiritual psychiatry is not about abandoning science. It is about widening the lens of care without lowering the standard.
Tune in LIVE this Sunday, Oct 25 at 11am ET (that’s Standard Time!) to hear Eben Alexander discuss NDEs and healing with Mark Pitstick, followed by live Q&A. Part of the Greater Reality Living & Healing program, you can join LIVE for FREE at
https://t.co/Zxm4gqgwyX
Eben Alexander joined Daniel Greenwald for a wide-ranging chat with listener Q&A on the Way of Service podcast. If you missed it live, here is the recording:
https://t.co/PCCdWMTywO
🇺🇦 ZELENSKYY'S MESSAGE TO THE AMERICAN PEOPLE
President Volodymyr Zelenskyy has delivered a direct and deeply serious message to Americans: If the United States officially sides with Russia, Ukraine will not be able to win this war. We will not be able to withstand it.
Zelenskyy expressed hope that Donald Trump would stand with Ukraine or, at the very least, maintain a neutral position rather than support the aggressor.
He also addressed the continuing restrictions on Starlink, stressing that the system's full functionality has still not been restored.
Zelenskyy said he hoped Trump would reconsider his decisions, which he described as mistakes that would benefit neither Ukraine nor the United States.
One of his most alarming statements concerned American intelligence. According to Zelenskyy, only the United States possesses the intelligence capabilities Ukraine needs to detect Russian ballistic missile launches in time. For three days, Ukraine did not receive that information.
These are not abstract diplomatic disagreements. They concern the ability to protect Ukrainian cities, intercept incoming missiles, and save civilian lives.
Ukraine is not asking America to fight its war. Ukraine is asking America not to help Russia win it.
The choice facing Washington is not simply between supporting Ukraine and remaining neutral. It is also about whether the United States will continue standing for the principles of sovereignty, freedom, and resistance to aggression.
Ukraine has been fighting for its survival. It must not be abandoned to the country trying to destroy it.
🇺🇦 STAND WITH UKRAINE.
Each tubulin has 86 aromatic amino acid rings with pi conjugation up the wazoo. These can extend tubulin to tubulin along helical pathways suitable for topological quantum error correction. Photosynthesis quantum coherence lasts femtoseconds (10^-12 secs) and microtubule quantum states at least 10^-8 secs. That’s 4 orders of magnitude longer, and potentially mesoscopic and macroscopic lengths along microtubules. We call that the quantum underground. The binding is weak but the number of collective weakly interacting oscillations is enormous.
Free Listening! Now posted, with English translation (in settings/CC): Keynotes from the Consciousness and the Invisible conference, held at the Grand Rex Paris in March 2026. Presentations by Eben Alexander & Karen Newell and many more!
https://t.co/8bpbzwimEL
Plan now to be in the Bahamas, March 9-14, 2027, for
Beyond the Veil Symposium: Awakening & Healing Through NDEs, featuring Eben Alexander, Karen Newell, Anita Moorjani, Jeffrey Long & Jeffery Olsen. Details and registration:
https://t.co/jeWN891htE
Join Dr. Eben Alexander LIVE today, October 14, at 4:00 PM Eastern on The Way of Service. Eben will talk about the life review, healing, and the one mind we all share, and take your questions live:
https://t.co/9TQgy6XYtV
REMINDER! Tonight watch the groundbreaking documentary, the premiere of A Greater Reality, preceded by a LIVE panel discussion. Details/ticketing: https://t.co/Pn671Pdo7z
The hard problem is accounted for by Penrose Objective Reduction, Nobel laureate Sir Roger Penrose’s proposed solution to the measurement problem in quantum mechanics. Here’s our 1996 paper in the Hard Problem special issue of J Consc Studies edited by Dave Chalmers https://t.co/wGJ7KIDWiF Superposition leading to OR threshold is portrayed as separated curvatures in spacetime geometry. When they collapse at time t and select a particular curvature/reality a now moment in time, an experience occurs nonalgorithmically. OR hasn’t yet been tested but the quantum states in microtubules necessary to orchestrate OR events (Orch) have been demonstrated at warm temperatures and are inhibited by anesthesia. https://t.co/MYpBnsTrrH
Orch OR has more explanatory power, biological connection and experimental evidence than all other theories combined. Selective specific action of anesthesia by dampening quantum states in microtubules correlates with clinical potency. https://t.co/KI2P9kGmHU
https://t.co/BLRNhgrsjL
STARTS TODAY! Archive X: Unexplained Phenomena is a new docu-series that begins streaming on October 1st on AMC Global Media and the Sundance Channel. Eben Alexander will be featured in Episode 5 on Near Death Experiences.
More info:
https://t.co/Lk18FMXmmP