Liz Pym

[Liz Pym @LizPym1]

@its_The_Dr That must hurt the deer, being pulled by his antlers. Good on you for saving him xx

[Liz Pym @LizPym1]

@Irina_exh Phone book

[Love Music @khnh80044]

That's control... awesome 💪❤️

[Keith Richards @officialKeef]

Wishing Mick a Happy Bithday! @MickJagger
One love, Keith

[Massimo @Rainmaker1973]

Researchers successfully cloned a single mouse and then repeatedly cloned its descendants for 58 generations over two decades, producing more than 1,200 animals from one original donor.

Yet the experiment ultimately ended in failure when the entire lineage collapsed due to accumulating genetic damage. This visual powerfully captures the central message of the study — that while cloning can produce healthy-looking individuals for many generations, it cannot sustain a viable lineage indefinitely in mammals.

The experiment, led by Teruhiko Wakayama and Sayaka Wakayama at the University of Yamanashi in Japan, began in 2005 using somatic cell nuclear transfer (the same technique that created Dolly the sheep). Early generations of clones appeared normal, lived typical lifespans, and even showed slightly improved cloning success rates at first. However, subtle problems emerged after roughly the 25th–27th generation.

Cloning efficiency declined sharply, and by the 57th generation, the success rate had fallen to just 0.6%. All mice in the 58th generation died within a day of birth, despite showing no obvious physical abnormalities.

Whole-genome sequencing revealed the underlying cause: harmful mutations accumulated progressively with each round of cloning. Without the genetic shuffling provided by sexual reproduction, deleterious changes — including point mutations, chromosomal abnormalities, and loss of the X chromosome in some cases — could not be purged. By the later generations, the mutation load had become overwhelming, leading to what researchers described as a form of “mutational meltdown.”

This long-term study provides the clearest evidence yet that mammals cannot maintain a species through cloning alone. Sexual reproduction remains essential for resetting genetic errors and maintaining long-term viability. The findings carry important implications for cloning technology, regenerative medicine, and our understanding of genome stability.

[Wakayama, S., Ito, D., Inoue, R., Ooga, M., Toshishige, M., Satoh, Y., Shiura, H., Kohda, T., Uchimura, A., & Wakayama, T. (2026). Limitations of serial cloning in mammals. Nature Communications. DOI: 10.1038/s41467-026-69765-7]

[Liz Pym @LizPym1]

@Emotion78687 Still rocking my world 🕯️

[Emotion & Music @Emotion78687]

Classic late-70s. An iconic track with timeless meaning. Can you name this song? 🤔🎶

[Vishal Khandelwal @safalniveshak]

If you have a father who can still pick up your call...call.

[🎼🌺Music Love♥️ @ThoNg676733]

She knocked it out of the park, and then some. Growing up with Elton John's music was awesome. Well done.

[WildandFree17 @Wildnfree1984]

@NewZealandMFA Freedom 🙌🏻

[Liz Pym @LizPym1]

Help STOP SEABED MINING! Sign the petition. Click the link.
https://t.co/cqaos3r7Dv

[Liz Pym @LizPym1]

Ocean Conservation Namibia - Humpback whale rescue
https://t.co/A62WoNCWXt

[Liz Pym @LizPym1]

@poppypride1 Never forget their selflessness. To all those who are living or have died, many thanks for our lives.

[Liz Pym @LizPym1]

@MickJagger Happy birthday Mick. Have the best of years xx 🏵️🎸🌞

[Greenpeace International @Greenpeace]

🚨 This is the video the deep sea mining industry doesn’t want you to see…

which is the best reason to watch and retweet ⬇️

#StopDeepSeaMining

[Liz Pym @LizPym1]

@MickJagger Good luck! NZ didn't do so well against Pakistan 😥

[Liz Pym @LizPym1]

@MickJagger What an amazing life! 🌞🏵️

[Liz Pym @LizPym1]

@Hannahwhite84 Snap! So beautiful aren't they 🥰

[The Royal Family @RoyalFamily]

The official coin effigy of His Majesty The King has been revealed by the @RoyalMintUK.

The King’s portrait will appear on a special £5 coin and 50p, as part of a memorial coin range released on Monday to commemorate the life and legacy of Queen Elizabeth II.