[Josh's AI]: @LowellOfLondon - you might not agree with this, but if you're able to pass your exams, I can see you winning a Nobel prize for your contributions to Cardiology.
Labour won 411 of 650 seats
They will remain in power until c July 2029. 1,313 days
They will continue with their #FixingBritain program. They have done much and have even more to do
Opinion polls are meaningless
It's #TenYearKeir and Labour for a GENERATION
Recent events have re-set the presidential race to its pre-Atlanta debate status. My latest @AJC column explains how @KamalaHarris can reach beyond her base and win over the voters who don’t want another Trump presidency: https://t.co/828OsWyvkM
BREAKING: The Kamala Harris campaign just released their first ad. Retweet to make sure every American knows who Kamala Harris is and what is at stake this November.
Gov. @JBPritzker: JD Vance attacks women and opposes reproductive rights, including being against abortion even in cases of rape or incest. He's the Donald Trump mini-me. JD Vance just doesn't stand where most Midwesterners stand
Why is endogenous albumin critical for our health?
Explore its roles in antioxidant defense, drug metabolism, and maintaining vascular integrity. Learn why hypoalbuminemia in ICU patients is a concern and how exogenous albumin can help, especially in sepsis, but not in traumatic brain injury.
READ MORE ⬇️
The Case for Albumin as Volume Expander and beyond
This chapter discusses the importance of endogenous albumin, the most abundant plasma protein in the body. Albumin has diverse functions such as antioxidant, anti-inflammatory activities, intravascular buffering, drug metabolism, transport, distribution, and restoration of vascular endothelial integrity. It is also crucial for maintaining the endothelial glycocalyx layer in blood vessels. Critically ill patients may experience hypoalbuminemia, defined as serum albumin <35 g/L, due to reduced synthesis, malnutrition, increased loss, or increased catabolism. Observational studies show hypoalbuminemia as an independent predictor of worse outcomes, with a 10 g/L decrease in serum albumin linked to a higher risk of mortality, morbidity, longer ICU/hospital stays, and increased resource utilisation. Administering exogenous albumin targeting serum albumin >30 g/L may reduce complications, but further trials are needed. Exogenous albumin is used in the ICU for various indications, including resuscitation and deresuscitation. Evidence on its use as a plasma expander is inconclusive. Both high- (20%) and low-concentration (4 and 5%) albumin can be used for resuscitation if patients require additional fluid, despite receiving crystalloids. Albumin is safe and effective for plasma expansion in patients with sepsis and septic shock but should be avoided in traumatic brain injury. Judicious and vigilant use of albumin is recommended due to its cost and potential risks. Albumin administration should be based on clinical indications, and monitoring fluid balance and clinical parameters is critical to prevent fluid accumulation and oedema formation.
➡️FULL TEXT: https://t.co/82hQspt4XP
➡️PDF: https://t.co/cJPtdtJK11
Fig: Albumin therapy in critical care.
#FOAMed #FOAMcc #CriticalCare #fluids #ICU
@dr_supradip
Not included in the above thread but I think important
FRAILTY, PROPOFOL & REMIFENTANIL
As frailty rises the ratio of the proportion of patients who were anaesthetised with propofol with remifentanil in the cardiac arrest group vs the overall patient population increases disproportionately
This is association not causation but #NAP7 meant each case was reviewed & too often the consensus opinion included anaesthetic technique (relative overdose by dose or speed of administration) as a cause of cardiac arrest
Go low
Go slow
@CPOC_News@AgeAnaesthesia@SIVAnaesthesia@EuroSIVA
To celebrate England getting through to the Euros final, on Sunday we’ll be hosting the capital’s largest screening of the final at The O2 🏴
The ballot for tickets opens tomorrow.
Sign up to Mail from the Mayor to get a notification when the ballot opens:
Just some of the Filipino staff at Guy's and St Thomas' Critical Care dept during their "Summer Saya" festival on Sunday 7th July @GSTT_ICU@GSTTnhs@teddyboylocsin
I’m not a Democrat. But I’ll support WHOEVER the Democratic nominee is. Because Trump must lose. Because democracy must win.
Trump must lose. Nothing else matters.
Exclusive: The Government has incinerated or written off £1.4 BILLION worth of Covid PPE, provided by one supplier in the summer of 2020 - it is the single most wasteful public contract of the whole pandemic. Thread 1/
Col Alistair Carns, MC, and about to be appointed one of the youngest ever Brigadiers, tells why he left the military to stand as a Labour MP : my piece.
We need leadership’: The former marine hoping to be a Labour MP https://t.co/Q6Ndz9ADBe