Three great works to achieve chemoselectivity and site selectivity and specificity of three amino acids residues in proteins are described in this Year in Review by @annkope.
Really excellent piece!
My first research highlight is out :)
It covers an exciting paper by Bradley, Geng and colleagues on the use of radiotherapy to site specifically activate chemotherapy through localised prodrug irradiation.
https://t.co/Hd0oE4osaa
#prodrugs#irradiation
Happy to share that I have recently started a new position as Associate Editor @NatRevChem! Enjoying getting started and meeting the team, and looking forward to reading all your impressive work!
Double-trouble: Check out our latest P(V)-electrophiles developed by @CEStieger.Diethynyl phosphinates enjoy a mรฉnage-a-trois with two thiol-nucleophiles! This technique expands our P(V)-toolbox towards protein double modification and disulfide-rebridging. https://t.co/lNTBcVRFn8