Luke Marchetti

PhD candidate in the Elmes Group, Maynooth University. Supramolecular chemist investigating squaramide-based anion transporters.

[Luke Marchetti @LukeMarchetti]

Excited to share my work so far on a new moiety in anion recognition: Amido-squaramides! Can't wait to investigate these cool new molecules further in the coming weeks 🧐 @rob_elmes @MaynoothChem #vMASCposter (poster number 22) #LoveIrishResearch

[Dr Jayne Pritchard @SlinkyScience]

My New Years resolutions:

1. Survive.
2. Finish PhD.

That’s it.

[Luke Marchetti @LukeMarchetti]

@SteelyBarrett

[Luke Marchetti @LukeMarchetti]

@Harlei_Martin @boconline @MaynoothChem Thanks hen 🥰

[Luke Marchetti @LukeMarchetti]

Absolutely delighted to have been awarded the @boconline postgraduate bursary for @MaynoothChem this morning. Thanks to everyone that tuned in to listen to my seminar on my PhD project.

[Luke Marchetti @LukeMarchetti]

@johno_mccarron @boconline @MaynoothChem Thanks John 🥳

[Luke Marchetti @LukeMarchetti]

Big shout out to my supervisor, @rob_elmes and the rest of the Elmes Group for their continued support!

[Luke Marchetti @LukeMarchetti]

@SteelyBarrett Thanks Ste! Congrats on the teaching award, you love to see it

[Luke Marchetti @LukeMarchetti]

@MaryanneCooks @MaynoothChem @boconline Thanks, Maryanne! Delighted to have received such a flattering introduction and to be able to present my work so far 😊

[Maryanne Dalton @MaryanneCooks]

Annual postgraduate awards ceremony this morning in @MaynoothChem . Huge thanks to @boconline for their long- standing and continued support of our postgraduate program! Huge congrats @LukeMarchetti for his ridiculously impressive research portfolio, amazing teaching & outreach!

[Luis Martínez-Crespo @lmartinezcrespo]

https://t.co/jMuS2exGlU. TRANSMEMBRANE TRANSPORT OF BICARBONATE UNRAVELED! Check out our VIP paper in @ChemEurJ . A great project developed with @HennieValkenier at the @ULBruxelles and with exceptional collaborators @Steve_JButler @APDBris @BambusurilGroup . Open access!

[Maynooth University Chemistry @MaynoothChem]

Huge congratulations to the Dept. Chemistry @MaynoothChem for achieving an Athena SWAN Bronze award 👏👏- reflecting work undertaken to advance gender equality for staff and students @MU_AthenaSwan @hea_irl @EqualityMU @MaynoothUni

[Elisa Granato @Prokaryota]

Getting ready to go to the lab knowing full well that the experiment didn't work

[Rob Elmes @rob_elmes]

Really pleased to see the latest review from our lab @MaynoothUni on '1,8-Naphthalimide based fluorescent sensors for enzymes' out in Coord Chem Rev. Lots of hard work from @ConorGeraghtyy and @ConorWynne4 @MuLonsdale @SSPCentre. Free to view until May https://t.co/f3Nhp3v6MP

[Jenya 🧪✨ @xhimichka]

nothing has such drastic effects on an organic chemist’s mood like NMR spectra

[TwistedDoodles @twisteddoodles]

Research romance #science #microbiology #AcademicValentines

[Luke Marchetti @LukeMarchetti]

@lmartinezcrespo @rob_elmes @MaynoothChem Thanks Luis 😊

[Luke Marchetti @LukeMarchetti]

Excited to share my work so far on a new moiety in anion recognition: Amido-squaramides! Can't wait to investigate these cool new molecules further in the coming weeks 🧐 @rob_elmes @MaynoothChem #vMASCposter (poster number 22) #LoveIrishResearch

[Luke Marchetti @LukeMarchetti]

@HennieValkenier @rob_elmes @MaynoothChem Thanks Hennie! We're still in the early stages of the project at the moment, pKa determination is coming up soon. I'd reckon that the pKa is slightly less than regular squaramides due to the carbonyl stabilising the conjugate base. No evidence yet, of course, just a hunch!

[Luke Marchetti @LukeMarchetti]

@lmartinezcrespo @rob_elmes @MaynoothChem I've been trying to grow crystals of the host:guest complex so we can do some x-ray crystallography to determine this. No success so far in obtaining crystals, but I'm continuing to try! (2/2)

[Luke Marchetti @LukeMarchetti]

@lmartinezcrespo @rob_elmes @MaynoothChem Hi Luis! It is definitely possible there is some intramolecular H-bonding affecting the anion binding. I'd guess that the conformation I have depicted in the poster is different than what's what is actually going on. (1/2)

[Luke Marchetti @LukeMarchetti]

@TABarendt - the squaramide would pick back up a H from the H2O, reversing the deprotonation. However, as water is a competitive H-bond donor for anions, the binding affinity would likely decrease in the presence of water! Thanks for your questions 😊(3/3)

[Luke Marchetti @LukeMarchetti]

Some more great results from the Elmes' Group! Can't wait to see what else Luke helps to produce over the next four years 👨‍🔬

[Dr Luke Edward Brennan (He/Him) @LukeBrennanChem]

Hi All! I'm delighted to be able to present a poster for vMASC 2020, highlighting some recent work from our group @rob_elmes - on Self-assembling Amphiphilic squaramides. Feel free to ask any questions regarding the work! hope you enjoy (poster 21) #vMASCposter #LoveIrishResearch

[Luke Marchetti @LukeMarchetti]

@TABarendt Chloride is basic enough to form a strong interaction but not basic enough to deprotonate. The size of Cl- is complementary to the binding site, also! If water was added the risk of deprotonation would *probably* be lessened due to H2O being a protic solvent (2/3)