MBF Bioscience

We create hardware and software for light sheet and multiphoton microscopy, fiber photometry, brain mapping, stereology, and image analysis.

[MBF Bioscience @MBFBioscience]

We’re having a great time at the Canadian Association for Neuroscience Meeting in Montréal!

We’re here today and tomorrow. If you’re attending, stop by our booth to see live demos of:

🔬 SLICE™ light sheet microscope for accessible, high-performance 3D imaging

🧠 FP3002 for flexible fiber photometry experiments

🧬 Software solutions for neuron tracing, stereology, brain mapping, multiphoton imaging, and more

We’d love to hear about your research and imaging workflows and connect with more of the neuroscience community!

https://t.co/vxDywLR9hS
@CAN_ACN #CAN2026 #Neuroscience #LightSheetMicroscopy #FiberPhotometry #BrainMapping #Stereology #Scienceinnovation #MBFBioscience

[MBF Bioscience @MBFBioscience]

We’re excited to share that our article, “Light-Sheet Microscope Design Puts Whole-Brain Imaging in Reach for Scientists,” is featured as the cover article in the latest issue of @TheBioPhotonics magazine!

The article highlights how the SLICE Light Sheet Microscope system combines projected light-sheet microscopy (pLSM), advanced optics for cleared tissue, and simplified system design to make high-performance whole-brain fluorescence imaging more accessible to researchers.

From subcellular-resolution imaging to large-scale brain mapping and connectomics, this approach brings advanced 3D imaging capabilities within reach of laboratories around the world.

A huge thank you to everyone involved in the development of this technology, especially Dr. Raju Tomer and collaborators at @Columbia University.

📖 Read more about how accessible light-sheet microscopy is accelerating neuroscience research and whole-brain imaging: https://t.co/mBsxp8BANw
.
.
#3Dimaging #SLICElightsheetmicroscope #lightsheetimaging #wholebrainimaging #neuroscience

[MBF Bioscience @MBFBioscience]

We’re excited to be heading to Montréal for the Canadian Association for Neuroscience Meeting 2026, taking place May 18–21!

If you’re attending, stop by our booth to see live demos of:
🔬 SLICE™: our award-winning light sheet microscope built to make high-performance 3D imaging more accessible and scalable.

🧠 FP3002 Fiber Photometry System: a flexible platform for recording neural activity in freely moving animals.

We'll also be showcasing solutions for neuron tracing, stereology, brain mapping, multiphoton imaging, and more.

Can’t wait to talk science, see what everyone’s working on, and connect with the neuroscience community!
https://t.co/vxDywLRH7q
.
.
@CAN_ACN #CAN2026 #Neuroscience #LightSheetMicroscopy #FiberPhotometry #BrainResearch #Microscopy #3DImaging #MBFBioscience

[MBF Bioscience @MBFBioscience]

We had a great time at the AQLM course this week showcasing the SLICE light sheet microscope and connecting with passionate researchers exploring the future of 3D imaging. 🔬

Thank you to the AQLM team and everyone who stopped by to see SLICE in action!

@MBLScience #LightSheetMicroscopy #3DImaging #Microscopy

[MBF Bioscience @MBFBioscience]

Join us at the Weinstein Cardiovascular Development & Regeneration Conference

📍 Hyatt Regency, Jersey City, NJ
📅 May 6–8

We’ll be showcasing 🔬SLICE, our award-winning light-sheet microscope built for fast, scalable, and accessible 3D imaging. If you’re working in vascular biology or large-scale 3D imaging, this is something worth seeing.

We’ll also be demoing Vesselucida 360, our powerful image analysis software for automated vessel reconstruction and advanced morphometric analysis.

Stop by to see live demos, explore our full suite of imaging solutions, and chat about your research. We’d love to connect!

https://t.co/RN2zt7ZpxR

#WeinsteinConference #VascularBiology #LightSheetMicroscopy #3DImaging #MBFBioscience

[MBF Bioscience @MBFBioscience]

New research is reshaping how we understand the adolescent brain, and Neurolucida played a key role. 🔬

A new study published in Science Advances found that during adolescence, a specific spine "hotspot" on primary somatosensory cortical neurons sees a dramatic, experience-dependent surge in dendritic spine density. When this accumulation failed to develop properly in mouse models of schizophrenia, researchers suggest that localized regulation of spine density is critical for maturing cognitive functions.

The study pairs Neurolucida with several imaging techniques, including super-resolution, confocal, and two-photon microscopy – creating precise maps of spine density and meaningful morphometric data.

The research reframes how we think about adolescent brain development and underscores the value of quantitative morphology in understanding the biology behind mental health disorders.

Huge congratulations to Ryo Egashira, Meng-Tsen Ke, Takeshi Imai, and team on this work.

🔗Read the full study: https://t.co/Q4CDCfmJdv
.
.
#Neuroscience #Neurolucida #BrainResearch #Adolescence #MentalHealth #MBFBioscience #sciencematters

[MBF Bioscience @MBFBioscience]

If you're at FOM 2026, come find us at booth 46! 👋

We're here showcasing how SLICE 🔬 is making high-resolution 3D imaging of cleared tissue more accessible, and today our own Matthew Fay is taking the stage to share how.

His talk will highlight how SLICE enables accessible, high-resolution 3D imaging of cleared tissues using advanced projected light-sheet microscopy (pLSM), along with a streamlined workflow for acquisition, visualization, and analysis.

📍 Session: New Developments in Commercial Instrumentation
🗓️ Today, March 30 | 16:30 – 16:50
📌 Room M12

Swing by the session or stop by our booth. We're always happy to geek out about imaging!

#FocusOnMicroscopy #LightSheetMicroscopy #SLICElightsheetmicroscope
#Microscopy #Neuroscience #3DImaging #FluorescenceImaging
#ClearedTissue #MBFBioscience

[MBF Bioscience @MBFBioscience]

Join us at Booth #46 at FOM 2026 in Stockholm (March 29 – April 1)

We're showcasing SLICE™, our award-winning light-sheet microscope for scalable, accessible, cost-effective high-performance 3D imaging, alongside our full suite of solutions including neuron tracing, stereology, multi-photon imaging, fiber photometry, brain mapping, and more.

📖 Attend Our Lecture: SLICE: Democratizing High-Resolution Light-Sheet Microscopy for Cleared Tissue Imaging
🗓 March 30 | 16:30–16:50 | Room M12

We look forward to seeing you in Stockholm! 🔬

https://t.co/UP34z6hiK1
#FOM2026 #FocusOnMicroscopy #LightSheetMicroscopy #SLICElightsheetmicroscope #Microscopy #Neuroscience #CellBiology #3DImaging #FluorescenceImaging #ClearedTissue

[Scitech Imaging & Optical Solutions @ScitechPtyLtd]

Trusted by neuroscientists worldwide, Neurolucida from @MBFBioscience enables precise tracing of neuronal structures from histological specimens & generates quantitative morphometric data.

📚 6,000+ citations advancing neuroscience research.

#Neuroscience #NeuroAnatomy

[Nathan O'Connor, PhD @nathanjoconnor]

Breaking the Size Barrier: Sub-Micron 3D Imaging with ClearScope https://t.co/UKFF3RgbYT
#microscopy #lightsheet #neuroscience @MBFBioscience

[MBF Bioscience @MBFBioscience]

We are excited to share our latest publication on ClearScope, a fully integrated light-sheet theta microscope for sub-micron resolution imaging without lateral size constraints. 🔬

Using light-sheet theta microscopy (LSTM), ClearScope enables high-resolution 3D imaging of large biological specimens including intact mouse brains and human brain tissue sections.

Read the open-access paper:
https://t.co/jkC3O0AtUd
.
.
@Columbia @nyulangone
#slicelightsheetmicroscope #3Dimaging #microscopy #neuroscience #Connectomics #Microscopy #OpenAccess

[MBF Bioscience @MBFBioscience]

🧠 NeuroArt Image Contest

Neuroscience isn't just about discovery. It's also about beauty.

We invite researchers, students, and imaging enthusiasts to submit their most captivating neuroscience images. Whether it’s neurons, brain tissue, or fluorescent microscopy, we want to see the artistry in your science.

Submit your image today!

🔗 https://t.co/W9dnJCNz6t
.
.
#NeuroArt #MicroscopyArt #NeuroscienceResearch #BrainScience #ScientificImaging #LifeScience

[MBF Bioscience @MBFBioscience]

We're thrilled to share some big news at MBF Bioscience - the first leadership change in our nearly 40-year history.

Jack Glaser is moving from President to CEO, and we’re proud to announce that @VeronicaPessino, PhD has been promoted from COO to President.

As CEO, Jack will be focused on long-term strategy and partnerships. Dr. Veronica will be at the helm running day-to-day operations. This isn't Jack stepping back, it's us stepping up to meet the challenges ahead in the research community.

After 39 years of building MBF, we've never been more excited about where we're headed. Please join us in congratulating Dr. Veronica!

🔗 https://t.co/QxXIbBrKVl
.
.
#MBFBioscience #Leadership #Neuroscience #Microscopy #CompanyNews

[MBF Bioscience @MBFBioscience]

🔬 Get an exclusive first look at the redesigned ScanImage interface — this Thursday!

Join us for a hands-on webinar to explore the new ScanImage UI, built to make your multiphoton imaging workflow faster and more intuitive.

In this session, you’ll learn:
✅ Guidance for transitioning from earlier versions
✅ New features and key enhancements
✅ Practical usage tips
✅ Live Q&A with the ScanImage team

📅 Jan 29, 2026 | PM ET
📝 Register: https://t.co/47K9O74KJT
.
.
#ScanImage #MultiphotonImaging #NeuroscienceTools #Microscopy #ImagingWorkflow #LifeScienceResearch #Webinar

[MBF Bioscience @MBFBioscience]

�� What if pathologists could see the whole “tree,” not just thin 2D slices?

Dr. Raju Tomer’s lab is advancing 3D histopathology with the SLICE™ light-sheet microscope, enabling fast, high-resolution volumetric imaging of human tissue and revealing critical spatial context in disease. 🔬

📖 https://t.co/fdalMvrO4h

#SLICElightsheetmicroscope #3Dimaging #LightSheetMicroscopy #3DHistopathology #Pathology #SpatialBiology #BreastCancerResearch #BiomedicalImaging

[MBF Bioscience @MBFBioscience]

Congratulations to Sudha Guttikonda and the team at the @MakinsonLab for winning the 2025 @Columbia Stem Cell Initiative Photo Contest!

This stunning image, captured on the SLICE light-sheet microscope, highlights the intricate structure of hiPSC-derived neuroimmune organoids and beautifully showcases microglia in all their morphological diversity within a brain organoid.

Truly inspiring work from an exceptional group of scientists. 👏🧠🔬

📷 https://t.co/nozjhsiRnP

#Microscopy #Organoids #Neuroscience #lightsheetmicroscopy #SLICElightsheetmicroscope #3Dimaging