MedB Lab

Research Laboratory of the Dept. of Internal Medicine B at @UK_Muenster and @uni_muenster.
Tweets represent personal views from lab members and @JonelTrebicka.

[MedB Lab @MEDB_LAB]

Strong presence from MedB at #EASLCongress2026 in Barcelona.

Great to see our clinicians and young investigators presenting and discussing current research in hepatology, cirrhosis and liver disease throughout this week’s congress.

#EASL #Hepatology #LiverDisease

[MedB Lab @MEDB_LAB]

MedB explains: Portal Hypertension

What it actually means:
Blood can’t flow properly through the liver, so pressure builds up in surrounding vessels.

Why it matters:
This silent pressure is what triggers many of the most dangerous liver complications.

[MedB Lab @MEDB_LAB]

One challenge that carries into every new year in Internal Medicine research:
negative results.
They shape better hypotheses, refine models, and prevent repetition,
yet they’re still underreported.
Progress depends on what we learn, not only on what we publish.

[MedB Lab @MEDB_LAB]

The holiday season changes hospital dynamics.
In Internal Medicine, we often see more decompensations, delayed presentations, and complex admissions, not fewer.
For research and care alike, this period is a reminder:
medicine doesn’t pause for the calendar.

[MedB Lab @MEDB_LAB]

Inside MedB
Not every scientific discussion leads to a breakthrough.

Many lead to refinement:
narrowing a question, challenging assumptions, deciding what not to pursue.

In hospital based research, progress often comes from clarity rather than novelty.

[MedB Lab @MEDB_LAB]

Research doesn’t advance in isolation.
It grows in the small moments:
🩺 clinicians comparing cases
📊 researchers reviewing data
💬 teams challenging ideas
Collaboration is the real engine of translational medicine.
#MedTwitter #Research #Science

[MedB Lab @MEDB_LAB]

Science moves faster when we work together. At MedB Lab, we're connected with hepatology research groups across Germany and Europe to push translational liver science forward. Stay tuned for updates post-ECLCB-9. #Hepatology #MedResearch

[MedB Lab @MEDB_LAB]

The ECLCB-9 meeting starts today in Groningen 🇳🇱 (Sept 24–26).
A key stage for liver cell biology research and collaboration.
#ECLCB9 #LiverResearch

[MedB Lab @MEDB_LAB]

The CLIF-C ACLF score predicts short-term mortality in acute-on-chronic liver failure more accurately than MELD or Child–Pugh.
Landmark validation led by Prof. Jonel Trebicka.
🔗https://t.co/GtSiXdUjAX #ACLF #Hepatology #MedResearch

[MedB Lab @MEDB_LAB]

Just 1 week until #ECLCB9 in Groningen 🇳🇱 (Sept 24–26).
Europe’s liver cell biology community will share new discoveries, foster collaboration, and spotlight young researchers.
We’ll be sharing highlights — stay tuned.
🔗 https://t.co/EFtywNBzfN

[MedB Lab @MEDB_LAB]

Portal hypertension = increased pressure in the portal vein system 🧬
It drives cirrhosis complications like:
• Varices
• Ascites
• Encephalopathy
At MedB Lab, we explore safer, non-invasive ways to measure and track it.
#AskMedB #Hepatology

[MedB Lab @MEDB_LAB]

Can we measure portal hypertension without invasive catheters? 🧬
✅ LSM & SSM
✅ FIB-4
✅ Emerging AI & omics
A 2023 review co-authored by Prof. @JonelTrebicka @MPraktiknjo, shows how non-invasive tools are reshaping hepatology.
🔗 https://t.co/p66ScYQstg #LiverResearch

[MedB Lab @MEDB_LAB]

Biomarkers are your body’s early warning system. 🧬
In hepatology, they help us:
• Detect liver disease earlier
• Track progression
• Tailor treatment
At MedB Lab, we decode these signals daily.
Which biomarker should we unpack next? 👇 #AskMedB

[MedB Lab @MEDB_LAB]

The ECLCB-9 meeting (European Club for Liver Cell Biology) happens Sept 24–26 in Groningen 🇳🇱.
We’ll be following closely and sharing key takeaways.
#LiverResearch #ECLCB9 #Hepatology
🔗 https://t.co/EFtywNBzfN

[MedB Lab @MEDB_LAB]

What if one treatment could lower 30-day mortality in ACLF by almost a third? 🧬
Prof. Jonel Trebicka’s 2025 meta-analysis shows:
✅ 30-day mortality ↓ (RR ~0.70)
✅ 90-day survival ↑ (RR 0.81)
✅ 1-year outcomes ↑ (RR 0.85)
🔗 PubMed: https://t.co/jKu3d68ckm

[MedB Lab @MEDB_LAB]

On 25 Sept 2025, MedB’s Gastroabende will cover screening for liver disease, with focus on alcohol-associated liver disease & viral hepatitis.

📍 Park Akademie Münster
🧑‍⚕️ Prof. A. Krag | 💬 Prof. @JonelTrebicka

🔗 https://t.co/QcFgeGMsgK

#Hepatology #MedB #LiverDisease

[MedB Lab @MEDB_LAB]

Not all cirrhosis behaves the same.

🧬 Distinct inflammasome activation patterns are associated with ACLF risk, even in patients without prior decompensation.

📖 https://t.co/kSJNDkewXG…
🔬 via @JHepatology, co-led by @JonelTrebicka

#ACLF #Hepatology #MedB #LiverDisease

[MedB Lab @MEDB_LAB]

🧠 What other organ can lose 70% of its tissue… and still bounce back?

Your liver isn’t just vital, it’s a regeneration powerhouse.
Understanding this capacity is key in surgery, transplantation, and chronic disease recovery.

#LiverFacts #Regeneration #Hepatology #MedB

[MedB Lab @MEDB_LAB]

This is why we believe in translational medicine — science that doesn’t stay in journals but transforms patient care.

#Cirrhosis #LiverHealth #EarlyDetection #MedB #PrecisionMedicine #Hepatology #TranslationalMedicine

[MedB Lab @MEDB_LAB]

🧠 Did you know?
Cirrhosis can develop silently — with no symptoms for years.
Often, by the time it’s diagnosed, the liver is already severely damaged.

Let’s talk about why timing is everything 👇

[MedB Lab @MEDB_LAB]

At MedB Lab, our mission is to flip the script:
⏱️ From late-stage rescue ➝ to early detection
🧪 From one-size-fits-all ➝ to precision-tailored care

Because in liver disease, early action = longer, better lives.