Martin Fernandez-Zapico Lab

oncology research, #pancreaticcancer, organoids, epigentics. @MayoClinic

[Biochemical Journal @Biochem_Journal]

New research study from the @MFZlab team: GLI1 interaction with p300 modulates SDF1 expression in cancer-associated fibroblasts to promote pancreatic cancer cells migration. https://t.co/PuuJQj2mpS

[Merih Deniz Toruner @DenizToruner]

Our latest research is on the cover of @Biochem_Journal!

[Senthil K Muthuswamy @3dorganoid]

Pleased to share our recent study on understanding TGFb-induced EMT in MCF10A cells by taking multidimensional approach. We report the presence of 4 discrete transition states during the EMT process. https://t.co/vJmUprvOo1

[Merih Deniz Toruner @DenizToruner]

Thankful to be a part of this article!https://t.co/XmPT0LkqYW

[Martin Fernandez-Zapico Lab @MFZlab]

A new article from the team at the @MFZlab. Great work, Renzo Vera!

[Martin Fernandez-Zapico Lab @MFZlab]

GLI1 interaction with p300 modulates SDF1 expression in cancer-associated fibroblasts to promote pancreatic cancer cells migration https://t.co/ONBWjcK5rp

[Martin Fernandez-Zapico Lab @MFZlab]

GLI1 interaction with p300 modulates SDF1 expression in cancer-associated fibroblasts to promote pancreatic cancer cells migration https://t.co/ONBWjcK5rp

[Martin Fernandez-Zapico Lab @MFZlab]

MFZ Lab Holiday Gathering 2023

[Anirban Maitra @Aiims1742]

A 20y timeline on stage at diagnosis & survival in #PancreaticCancer.
Per Cancer Statistics 2003, the five year survival of pancreatic cancer overall was 4%.
In 2022 it is 12%.
Most of those survival gains have come in localized (17% 👉🏽 44%) & regional (7% 👉🏽 15%) disease.

[Gianrico Farrugia @GFarrugiaMD]

This year, Mayo Clinic had the honor of providing hope and healing to more than 1.4 million patients and their loved ones. Reflecting on 2022, I am proud of the ways we have created remarkable new ways to shape and transform the future of health care. Happy Holidays to all.

[Toni Choueiri, MD @DrChoueiri]

Ok, the numbers say it all…
#WorldCup #argentinavspoland

[Karim Sadjadpour @ksadjadpour]

USA’s Antonee Robinson consoles Iran’s Ramin Rezaian after America’s victory. Iran’s regime has tried hard to brainwash its people against the US, but most Americans who’ve been to Iran will tell you it’s among the friendliest places they’ve ever visited.

[The Washington Post @washingtonpost]

Remember when Argentina lost its World Cup opener to Saudi Arabia? Yeah, it does seem like a long time ago now. The Albiceleste and Poland advance out of Group C. https://t.co/Xaehs75uYO

[Anirban Maitra @Aiims1742]

Targeting OXPHOS in frontline setting in advanced #PancreaticCancer - #clinicaltrial open & enrolling at @MDAndersonNews and led by @DrShubhamPant
https://t.co/4udD6VgkEQ

[Anirban Maitra @Aiims1742]

.@theNCI wants to hear from you.
How will precision prevention of two cancers with rising incidence & high mortality rates - #PancreaticCancer & #LiverCancer - become a reality?Anyone can respond to the RFI (academia, industry, advocacy orgs, lay public).
https://t.co/ieJiF254xk

[Gauri Kumbhar @drgauri_k]

November is a pancreatic cancer awareness month. We took this opportunity to shine a light on this disease and made an informative video to raise public health awareness about pancreatic cancer. #PancreaticCancerAwarenessMonth #pancreaticcancer

[Paperbirds_Oncology @PaperbirdsO]

New article: Culture media composition influences patient-derived organoids ability to predict therapeutic response in gastrointestinal cancers https://t.co/e2Rpnb9uCC #livercancer #oncology

[Anirban Maitra @Aiims1742]

Important preclinical study in @JCI_insight from @MayoClinic team:
Culture media composition influences patient-derived organoids ability to predict therapeutic response in gastrointestinal cancers (#PancreaticCancer, #ColorectalCancer)
https://t.co/sIjPwkZExa
Mind your media!

[Hossein Moosavi @hmoosavi_tw]

Pretty significant for precision medicine 💊 ❗️
A profound influence of culture media on PDO phenotype, significant difference in response to SoC chemotherapies, distinct morphologies, and transcriptomes between media within the same PDOs cultures

[Rémy Nicolle @RemyNicolle]

Still a lot of work to do to trust organoids:

⚠️Culture conditions impact drug response

https://t.co/uYD35i5jL5

[IU Simon Comprehensive Cancer Center @IUCancerCenter]

In a recently published article in @JCI_insight Jason Doles (@jdoles99), PhD, and his colleagues evaluated a patient-derived organoid’s ability to predict clinical response to gastrointestinal cancers. Learn more: https://t.co/wotJvD8jgI.