MJ Hundertmark🫀MD, PhD

Clinical Scientist @inselspital + @UniofOxford with special interest in HF&energy metabolism. Ex-Chair @dgimev Junge DGIM; Read more than Tweet

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

Following our work establishing HFpEF’s energetic gradient correlates with its disease severity and assessing SGLT-2i’s potential to correct the energetic deficit in HF, ninerafaxstat appears to be able to positively modulate the heart’s energetic state in cardiometabolic HFpEF

[Circulation @CircAHA]

In a phase 2 study, Ninerafaxstat (trimethazidine analogue) is well-tolerated and improved mycoardial energetics in participants with obesity and diabetes https://t.co/fDk2gt8xuL

[Circulation @CircAHA]

In a phase 2 study, Ninerafaxstat (trimethazidine analogue) is well-tolerated and improved mycoardial energetics in participants with obesity and diabetes https://t.co/fDk2gt8xuL

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

@pnatarajanmd @CircAHA We’re certainly very happy with the results. We’ve assessed the energetic deficit in HFpEF previously (https://t.co/eqdSuoxpRG) and have also tested whether Empagliflozin would correct it in a RCT in HF patients (https://t.co/9x83xgyHd7)

[Pradeep Natarajan @pnatarajanmd]

Ninerafaxstat, which promotes myocardial glucose oxidation via partial fatty acid oxidation inhibition & enhances cellular NAD+ pool, ↑ imaging-assessed myocardial energetics & ↑6MWD vs placebo in N=42 with T2D & obesity with & without HFpEF https://t.co/2ll5eUrwYb @CircAHA

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

@WilfriedMullens Very well deserved and a win for the HFA

[Harriette Van Spall, MD MPH 🇨🇦 @hvanspall]

Reviewers often request inappropriate #statistical testing

This📄 discusses how to respond when reviewers ask you to add p-values to CIs & to dichotomize all your inferences

Consider
- size of Tx effects
- directionality
- precision
- consistency

#stats
https://t.co/MEYpOZbkRL

[Sarah Birkhoelzer @sarah.theheartdoc @BirkhoelzerS]

Let’s change the world together 🤲🏻

If you want to make a difference 🙌collaborate.
I collaborated with these wonderful people to inspire #WomenInSTEM
Many more missing on the 📸

🐥Re-tweet if you agree .. let’s challenge that algorithm of old thinking 🧐

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

@ShvetaMonga @eva_sammut @cardiolewis @Ollie__Rider @DrWillWatson @DrAnvesha_Singh @EylemLevelt @dr_vimalraj @DaghemSafa @BirkhoelzerS @jenniferjrayner @KhanKheil88 Great seeing you, too

[Shveta Monga @ShvetaMonga]

Absolutely brilliant #CMR2024!Great opportunity to learn, share knowledge and catch up with old & new friends! @eva_sammut @cardiolewis @Ollie__Rider @DrWillWatson @MJHundertmark @DrAnvesha_Singh @EylemLevelt @dr_vimalraj @DaghemSafa @BirkhoelzerS @jenniferjrayner @KhanKheil88

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

@AhmetBarutcu Thanks Ahmet

[Will Watson @DrWillWatson]

Excellent publication. Not seen this expressed so starkly before (and correlation of course isn’t causation) but increasing privatisation worsens patient outcomes.

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

@DrWillWatson That’s neat indeed. @GauravGulsin could you create a short 🧵 on this?

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

@venkmurthy I like the part in which the ‘Radiologist’ confirms the ecg diagnosis 😂

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

Early bird session with great insights @YoungDgk with @ViclouiseJ

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

@CLerchenmueller @DGK_org @AG31_DGK Thanks for the invitation @DGK_org @YoungDgk . Always a pleasure to experience the excellent meetings

[Djawid Hashemi @DjawidHashemi]

🌟👩‍⚕️👨‍⚕️Moin!👨‍⚕️👩‍⚕️🌟 Auch bereit für die #DGKHerztage? 🍁🫀
📢 👥Gemeinsam mit @JBauersachsMD, @luedike, @realdocdan werden wir das Neueste zur #Herzinsuffizienz präsentieren!🤩 📸
📸 Freut euch auf spannende Updates und Diskussionen! 🙌 @DGK_org @YoungDGK @agep_DGK @AGIKinterv

[Konstantinos I. Bougioukas @Bugiukas]

A new cover for the online textbook "Practical Statistics in Medicine with R"!
https://t.co/ZVY09ly0Gl

#rstats #QuartoPub #tidyverse #dataviz #statistics #datascience

[Young DGK @YoungDgk]

Zum Abschluss der Komorbiditäten - @MJHundertmark mit einem spannenden Vortrag zur Herzinsuffizienz und Niereninsuffizienz
@SamiraSoltaniMD @FlorianKahles @Hannah_Billig_ @AnnaHohneck @Hannah_Billig_ @MAlZaidi_ @ViclouiseJ

[Young DGK @YoungDgk]

@FlorianKahles nun mit einem seiner Lieblingsthemen - Herzinsuffizienz und Diabetes
@MJHundertmark @BerkanKurtMD @ChristophMaack

[MJ Hundertmark🫀MD, PhD @MJHundertmark]

@HolgerNef @SamuelSossalla @mmamas1973 @mirvatalasnag @KardiologieHH @Steph_Achenbach @SABOURETCardio @kaschenke Many congratulations and godspeed for the way ahead